Preferred Language
Articles
/
8RdBkpIBVTCNdQwCy7eU
Preparation and In vitro/Ex vivo Evaluation of Nanoemulsion-Based in Situ Gel for Intranasal Delivery of Lasmiditan
...Show More Authors

Lasmiditan (LAS) was formulated as a nanoemulsion based in situ gel (NEIG)with the aim of improving its oral bioavailability via application intranasally. The solubility of LAS in oils, emulsifiers, and co-emulsifiers was determined to identify nanoemulsion (NE)components. Phase diagrams were constructed to identify the area of nanoemulsification. LAS NE was formulated using the spontaneous nanoemulsification method. Four NEs (F19, F24, F31, and F34) containing 7-15 % oleic acid (OA) as an oily phase, 40-55% labrasol (LR), and transcutol (TC) as emulsifier mixture at (1:1), (2:1), (3:1), and (1:2) ratio with 30-53 % (w/w) aqueous phase, having suitable optical transparency of 95–98%, globule size of 104-140 nm and polydispersity of 0.253–0.382 were selected for ex vivo permeation study. F31 with the highest flux value (2.32 ± 0.01 mg/cm2.min) relative to the other NEs. It achieves an enhancement ratio of 3.3 as compared to LAS aqueous suspension (8% LAS) also it achieves a significantly higher value of permeability coefficient. F31 was selected for the incorporation of different percentages of pH-sensitive in situ gelling polymer (Carbopol 934) to prepare NEIGs 4,5 and 6. The gel strength, pH, gelation time, and viscosity were predicted for the prepared NEIGs. In vitro release and ex vivo, nasal permeation were determined for NEIG5, which exerts comparable release and permeation values as F31 with more residence time in order to overcome the normal nasal physiological clearance.  

Scopus Crossref
View Publication
Publication Date
Fri Jan 01 2021
Journal Name
Aip Conf. Proc.
Preparation of nanostructured MnO2/carbon fiber composite electrode for removal of Cu2+ ions from aqueous solution by electrosorption process
...Show More Authors

The nanostructured Manganese dioxide/Carbon fiber (CF) composite electrode was prepared galvanostatically using a facile method of anodic electrodeposition by varying the reaction time and MnSO4 concentration of the electrochemical solution. The effects of these parameters on the structures and properties of the prepared electrode were evaluated. For determining the crystal characteristics, morphologies, and topographies of the deposited MnO2 films onto the surfaces of carbon fibers, the X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and atomic force microscopy (AFM) techniques were used, respectively. It found that the carbon fibers were coated with γ-MnO2 with a density that increased with increasing the de

... Show More
View Publication Preview PDF
Scopus (3)
Crossref (2)
Scopus Crossref
Publication Date
Tue Jun 30 2015
Journal Name
International Journal Of Computer Techniques
Multifractal-Based Features for Medical Images Classification
...Show More Authors

This paper presents a method to classify colored textural images of skin tissues. Since medical images havehighly heterogeneity, the development of reliable skin-cancer detection process is difficult, and a mono fractaldimension is not sufficient to classify images of this nature. A multifractal-based feature vectors are suggested hereas an alternative and more effective tool. At the same time multiple color channels are used to get more descriptivefeatures.Two multifractal based set of features are suggested here. The first set measures the local roughness property, whilethe second set measure the local contrast property.A combination of all the extracted features from the three colormodels gives a highest classification accuracy with 99.4

... Show More
Preview PDF
Publication Date
Sat Dec 03 2022
Journal Name
Tikrit Journal Of Pure Science
A Pixel Based Method for Image Compression
...Show More Authors

The basic solution to overcome difficult issues related to huge size of digital images is to recruited image compression techniques to reduce images size for efficient storage and fast transmission. In this paper, a new scheme of pixel base technique is proposed for grayscale image compression that implicitly utilize hybrid techniques of spatial modelling base technique of minimum residual along with transformed technique of Discrete Wavelet Transform (DWT) that also impels mixed between lossless and lossy techniques to ensure highly performance in terms of compression ratio and quality. The proposed technique has been applied on a set of standard test images and the results obtained are significantly encourage compared with Joint P

... Show More
View Publication
Crossref (1)
Crossref
Publication Date
Tue Feb 01 2022
Journal Name
Iraqi Journal Of Science
New Root-based Stemmer for Arabic Language
...Show More Authors

Importance of Arabic language stemming algorithm is not less than that of other languages stemming in Information Retrieval (IR) field. Lots of algorithms for finding the Arabic root are available and they are mainly categorized under two approaches which are light (stem)-based approach and root-based approach. The latter approach is somehow better than the first approach. A new root-based stemmer is proposed and its performance is compared with Khoja stemmer which is the most efficient root-based stemmers. The accuracy ratio of the proposed stemmer is (99.7) with a difference (1.9) with Khoja stemmer.

View Publication Preview PDF
Publication Date
Mon Jan 10 2022
Journal Name
Iraqi Journal Of Science
Genetic Algorithm based Clustering for Intrusion Detection
...Show More Authors

Clustering algorithms have recently gained attention in the related literature since
they can help current intrusion detection systems in several aspects. This paper
proposes genetic algorithm (GA) based clustering, serving to distinguish patterns
incoming from network traffic packets into normal and attack. Two GA based
clustering models for solving intrusion detection problem are introduced. The first
model coined as handles numeric features of the network packet, whereas
the second one coined as concerns all features of the network packet.
Moreover, a new mutation operator directed for binary and symbolic features is
proposed. The basic concept of proposed mutation operator depends on the most
frequent value

... Show More
View Publication Preview PDF
Publication Date
Thu Oct 21 2021
Journal Name
The 3rd Al-noor International Conference Of Science And Technology 2021 Muscat-oman
Gama Platform Survey for Agent-Based Modelling
...Show More Authors

The agent-based modeling is currently utilized extensively to analyze complex systems. It supported such growth, because it was able to convey distinct levels of interaction in a complex detailed environment. Meanwhile, agent-based models incline to be progressively complex. Thus, powerful modeling and simulation techniques are needed to address this rise in complexity. In recent years, a number of platforms for developing agent-based models have been developed. Actually, in most of the agents, often discrete representation of the environment, and one level of interaction are presented, where two or three are regarded hardly in various agent-based models. The key issue is that modellers work in these areas is not assisted by simulation plat

... Show More
View Publication
Publication Date
Thu Jan 01 2015
Journal Name
Journal Of Theoretical And Applied Information Technology
Graph based text representation for document clustering
...Show More Authors

Advances in digital technology and the World Wide Web has led to the increase of digital documents that are used for various purposes such as publishing and digital library. This phenomenon raises awareness for the requirement of effective techniques that can help during the search and retrieval of text. One of the most needed tasks is clustering, which categorizes documents automatically into meaningful groups. Clustering is an important task in data mining and machine learning. The accuracy of clustering depends tightly on the selection of the text representation method. Traditional methods of text representation model documents as bags of words using term-frequency index document frequency (TFIDF). This method ignores the relationship an

... Show More
Preview PDF
Scopus (15)
Scopus
Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Fuzzy Based Clustering for Grayscale Image Steganalysis
...Show More Authors

Fuzzy Based Clustering for Grayscale Image Steganalysis

View Publication Preview PDF
Publication Date
Mon Jan 01 2024
Journal Name
International Journal Of Clinical And Diagnostic Pathology
Evaluation of transferrin saturation and serum ferritin in assessing body iron status in patients with end stage renal disease
...Show More Authors

The study aimed to evaluate the benefits of transferrin saturation percentage (TSAT) and serum ferritin in assessing body iron status, which can influence erythropoietin treatment in patients with ESRD. Forty end-stage renal disease patients on regular hemodialysis participated in this study. Clinical data were obtained. Serum iron, total iron binding capacity, transferrin saturation, ferritin, albumin, creatinine, and C-reactive protein were investigated. Thirty healthy people were enrolled as a control group. ESRD patients had a mean age of 45.1±13.9 years, with 60% being males. They exhibited significantly lower hematocrit (25.3±6.5%), and higher platelet (285.7±148.1x10^9/L) and WBC (9.4±3.1x10^9/L) counts compared to healthy contro

... Show More
View Publication
Crossref
Publication Date
Sun Jan 30 2022
Journal Name
Iraqi Journal Of Science
Natural Radioactivity Evaluation and Radiological Peril in some soil specimens of Al-Taimeem Area in Al-Anbar Province, Iraq
...Show More Authors

In the present work, the radioactivity of ten soil specimens has been measured, which were gathered from various sites from AL-Taimeem area in Al-Anbar province, The qualitative activity of natural radionuclides 238U, 232Th and 40K for soil specimens were evaluated by utilizing gamma-ray spectroscopy with NaI(Tl) detector of (3"×3") dimension. The results revealed that, the qualitative activity, for 238U was varied from (14.730 Bq/kg) to (28.070 Bq/kg), for 232Th was varied from (16.510 Bq/kg) to (29.480 Bq/kg), for 40K was varied from (143.820 Bq/kg) to (231.550 Bq/kg) ,with an average values of (21.152±2.98 Bq/kg) , (24.219±3.93 Bq/kg), (190.720±22.20 Bq/kg), success

... Show More
View Publication Preview PDF
Scopus (5)
Crossref (1)
Scopus Crossref