doi:10.13005/ojc/330567

Details

Publication Date

Mon Aug 14 2017

Journal Name

Oriental Journal Of Chemistry

Volume

33

Issue Number

5

DOI

10.13005/ojc/330567

Choose Citation Style

Statistics

(2)

Leucine Aminopeptidase from Arachis hypogaea L. Seeds Partial Purification and Characterization

: Leucine amion peptidase (LAP)

Arachis hypoaea L. seeds

Purification

Taghreed

...Show More Authors

Leucine amino peptidases (LAP; EC 3.4.11.1) constitute a diverse set of exopeptidases that catalyze the hydrolysis of leucine residues from the amino-terminal of protein or peptide substrates, (LAP) are present in animals, plants, and microbes. In this study, leucine amino peptidase was purified partial from Arachis hypogaea seeds by using gel filtration chromatography Sephadex G-100. The enzyme was purified 3.965 fold with a recovery of 29.4%. Its pH and temperature optimum were(8.7) and (37oC), respectively. The results show novel properties of LAP from Arachis hypogaea L. or peanut. The Km value for LAP (77 mM), with V max (1538 m mole min-1). We recommend a separate isoenzymeof the enzyme (LAP) from Arachis hypogaea on L. peanut seeds and study the kinetic qualities of each of them

Publication Date

Thu Jul 11 2024

Journal Name

Maaen Journal For Medical Sciences

Pharmacological Supplements Efficacy in Management of chronic pain associated with Sickle Cell Disease: A narrative review

Chronic pain

L-arginine

Nitric oxide

Omega 3

Opioid alternatives

SCD pain

Sickle cell anemia

Supplements

Vitamin D

Zinc

Ahmad

Samer Imad

...Show More Authors

Sickle cell disease (SCD) is a hereditary ailment that can cause severe pain and suffering to people who are affected. However, with continued investment in research and treatment options, we can make progress towards improving the lives of those with SCD. Over 40% of patients experience painful vaso-occlusive crises (VOCs), so we must work towards finding solutions and providing support for those living with this condition, These episodes, a hallmark of SCD, significantly contribute to morbidity, mortality, and a diminished quality of life, while also incurring substantial healthcare costs. Chronic pain particularly affects older adolescents and adults with SCD, with over half reporting daily discomfort. Opioid-based analgesics, though sti

View Publication Preview PDF

Publication Date

Thu Apr 06 2023

Journal Name

Materials Science Forum

Study of the Effect of Ce 3+ on the Gas Sensitivity and Magnetic Properties of CuxCe0.3-XNi0.7Fe2O4 Ferrite Nanoparticles

Tagreed M.

...Show More Authors

This study includes the preparation of the ferrite nanoparticles Cu_xCe_0.3-XNi_0.7Fe₂O₄ (where: x = 0, 0.05, 0.1, 0.15, 0.2, 0.25, 0.3) using the sol-gel (auto combustion) method, and citric acid was used as a fuel for combustion. The results of the tests conducted by X-ray diffraction (XRD), emitting-field scanning electron microscopy (FE-SEM), energy-dispersive X-ray analyzer (EDX), and Vibration Sample Magnetic Device (VSM) showed that the compound has a face-centered cubic structure, and the lattice constant is increased with increasing Cu ion. On the other hand, the compound has apparent porosity and spherical particles, and t

View Publication

(1)

(2)

Publication Date

Wed Nov 30 2022

Journal Name

Iraqi Journal Of Science

New Generalizations of Soft LC-Spaces

Soft K(NpC)-space

soft L(NpC)-space

soft F ̃_σ-Np-closed set

soft NpL_k- spaces

for k=1

2

3

4

soft NP-space

soft NpQ-set space

Haider Juber

Sabiha I.

...Show More Authors

In this article, we introduce a new type of soft spaces namely, soft spaces as a generalization of soft paces. Also, we study the weak forms of soft spaces, namely, soft spaces, soft spaces, soft space, and soft spaces. The characterizations and fundamental properties related to these types of soft spaces and the relationships among them are also discussed.

View Publication Preview PDF

(2)

Publication Date

Sat Dec 01 2012

Journal Name

Advances In Bioresearch

Cytotoxicity of Miltefosine against Leishmania majorPromastigotes

Leishmaniasis has poor vaccination trials and the available drugs have side effects on patients. Therefore

development ofnew chemicals is important for public health. Miltefosine is the first drug used for oral treatment of visceral leishmaniasis.Previous studies approved that miltefosine is an effective treatment against visceral leishmaniasis

the visceral form ofLeishmania

and also on L. major

the cutaneous form of Leishmania. Here

we investigated the in vitro cytotoxicity ofmiltefosine on the procyclic promastigotes forms of L. major. Different concentrations of miltefosine were investigatedagainst the flagellated form of L. major

and results showed that miltefosine has inhibited the in vitro proliferation of theparasite

approving the cytotoxic effect of the compound on Leishmania

EC50 was determined after 24 hours exposure forthe drug and it was 1.54 μM. Our findings indicate that miltefosine has a cytotoxic effect on the insect stage of the old worldL. major and can be a new anti-Leishmanial drug

Hayder

...Show More Authors

View Publication Preview PDF

1 2 3 4 ... 1720 1721 1722 1723