Serum levels of iron,copper,ceruloplasmin and transferrine were estimated in three groups of patients with ?- thalassemia: 24 patients have splenectomy thalassemia major, 29 patients have non splenectomy thalassemia major and 19 patients have thalassemia intermedia , data were compared to normal and pathological controls (anemia and minor). There were significant increase in trace element levels in all studied groups of pateints as compared to normal and pathological controls. Also there were a significant increase in ceruloplasmin levels,While the result revealed that there were a significant decrease in transferrine levels in all groups of patients studied as compared to normal and pathological controls. The result also indicate that the

A transdermal drug delivery system (TDDS) is characterized by the application of medications onto the skin's surface to deliver drugs at a controlled and predefined rate through the skin. Spanlastics, an elastic nanovesicle capable of transporting various pharmacological substances, shows promise as a drug delivery carrier. It offers numerous advantages over traditional vesicular systems applied topically, including enhanced stability, flexibility in penetration, and improved targeting capabilities. This study aims to develop meloxicam (MX)-loaded spanlastics gel as skin delivery carriers and to look into the effects of formulation factors like Tween80, Brij 35, and carbopol concentration on the properties of spanlastics gel, like pH, drug

Ibuprofen is one of the most important members of NSAIDs, named aryl propionic acid derivative. Isatin (1H-indole-2,3-dione) is an important molecule of heterocyclic compounds that have many biological activities. This work illustrates the synthesis of new ibuprofen-isatin derivatives by connecting ibuprofen hydrazide with different isatin derivatives by a condensation reaction, followed by characterization by fourier-transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR) spectroscopy. The anti-inflammatory activity was evaluated by using the egg-white induce edema method for all the synthesized compounds (5-8), the compounds 5 and 6 showed better anti-inflammatory activity than ibuprofen as a standard

     A computer simulation was conducted using Optics Software for Layout and Optimization (OSLO) to design a Cassegrain telescope system for on-axis rays. In order to establish such a telescope, the two mirrors of the optical system were designed as spherical surfaces: a concave mirror and a convex mirror. The obscuration ratios of the Cassegrain telescope's secondary mirror were examined using different values, which ranged between 0.1 and 0.3, to determine the best obscuration ratio. This work adopted three criteria to decide which obscuration ratio is the best for the Cassegrain telescope. The first criterion was the number of rays that reached the final image. The second criterion was calculating the modulation transfer function

Schizophrenia(SCZ) is oneof the most destructive and complicated chronic diseases of the human nervous system. Serotonin receptors have been involved in the pathophysiology of psychiatric disorders including schizophrenia. Fortyschizophrenia subjects (14females and 26 males) with an age range of 23– 57 years were enrolled, in addition to twenty healthy control subjects (10female and 10 male) with an age range of 19-44 years.

This study aimed to evaluate the frequency of one single nucleotide polymorphism (SNP), namelyrs643627 in HTR2Agene,inIraqi patients with schizophrenia in comparison with controls, along with the association between this SNP and the incidence of schizophrenia.

The genetic variantrs6436

     The idea of the paper is to consolidate Mahgoub transform and variational iteration method (MTVIM) to solve fractional delay differential equations (FDDEs). The fractional derivative was in Caputo sense. The convergences of approximate solutions to exact solution were quick. The MTVIM is characterized by ease of application in various problems and is capable of simplifying the size of computational operations.  Several non-linear (FDDEs) were analytically solved as illustrative examples and the results were compared numerically. The results for accentuating the efficiency, performance, and activity of suggested method were shown by comparisons with Adomian Decomposition Method (ADM), Laplace Adomian Decompos

Compression of speech signal is an essential field in signal processing. Speech compression is very important in today’s world, due to the limited bandwidth transmission and storage capacity. This paper explores a Contourlet transformation based methodology for the compression of the speech signal. In this methodology, the speech signal is analysed using Contourlet transformation coefficients with statistic methods as threshold values, such as Interquartile Filter (IQR), Average Absolute Deviation (AAD), Median Absolute Deviation (MAD) and standard deviation (STD), followed by the application of (Run length encoding) They are exploited for recording speech in different times (5, 30, and 120 seconds). A comparative study of performance