A study of Immune Response in Golden Hamsters to Vaccinate against Leishmaniasis with Killed Promastigotes of Leishmania tropica
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Publication Date
Thu Jun 13 2024
Journal Name
Al-rafidain Journal Of Medical Sciences ( Issn 2789-3219 )
Association of the MDR1 Variants (rs2032582 and rs2032583) with Steroid Response in Iraqi Children with Idiopathic Nephrotic Syndrome
Background: Several studies linked the development of steroid-resistant nephrotic syndrome (SRNS) to genetic variations in the multidrug resistance 1 (MDR1) gene, though a disparity in findings was underlined among children with different ethnic origins. Objective: This study examined the relationship between MDR1 variants (rs2032582 and rs2032583) and the risk of developing SRNS in Iraqi patients with idiopathic nephrotic syndrome (INS). Methods: This case-control study included children with steroid-sensitive INS (SSNS; n=30) and SRNS (n=30) from the Babylon Hospital for Maternity and Pediatrics. Sanger sequencing was used to determine the participants’ genotypes. Results: The rs2032582 genotypes and alleles were not associated
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Publication Date
Tue Jun 04 2019
Journal Name
Jordan Journal Of Biological Sciences
Differential Expression for Genes in Response to Drought and
Salinity in Ruta graveolens Plantlets
Gene expression
Drought and salinity stress
Callus culture
Ruta graveolens
Abiotic stress-induced genes may lead to understand the response of plants and adaptability to salinity and drought stresses. Differential display reverse transcriptase – polymerase chain reaction (DDRT-PCR) was used to investigate the differences in gene expression between drought- and salinity-stressed plantlets of Ruta graveolens. Direct and stepwise exposures to drought- or salt-responsive genes were screened in R. graveolens plantlets using the DDRT technique. Gene expression was investigated both in the control and in the salt or drought-stressed plantlets and differential banding patterns with different molecular sizes were observed using the primers OPA-01 (646,770 and 983 pb), OPA-08 (593 and 988 pb), OPA-11 (674 and 831 pb
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Publication Date
Thu Jun 01 2023
Journal Name
Neurology Asia
Integrin alpha-4 gene polymorphism in relation to natalizumab response in multiple sclerosis patients
Objectives: The aim of this study was to assess the possible the association between +3061 (G>A, rs1143676) missense mutation in exon 24 of the integrin α-4 subunit (ITGA-4) gene and the response to natalizumab in a sample of Iraqi multiple sclerosis patients. Methods: A sample of 59 patients with multiple sclerosis (16 males and 43 females; mean age of 32 years; age range of 15 to 52 years) receiving natalizumab for at least 12 consecutive months were involved in the study between March and August/ 2022. The sample was categorized into two groups according to their response to natalizumab treatment (responders and non-responders). Polymerase chain reaction and Sanger’s sequencing for the extracted deoxyribonucleic acid was pe
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Publication Date
Sun Sep 30 2007
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
A Study in to the Dynamic Behavior of Packed Distillation Column
packed distillation columns
The study of the dynamic behavior of packed distillation column was studied by frequency response analysis using Matlab program. A packed distillation column (80 mm diameter) (2000 mm height) filled with glass packing (Raschig Rings 10mm), packing height (1500 mm) has been modified for separation of methanol-water mixture (60 vol%). The column dynamic behavior was studied experimentally under different step changes in, feed rate (±30%), reflux rate (±22%), and reboiler heat duty (±150%), the top and bottom concentration of methanol were measured. A frequency response analysis for the above step response was carried out using Bode diagram, the log modulus and the phase angle were used to analyze the process model. A Matlab progra
... Show MorePublication Date
Thu Oct 01 2009
Journal Name
Baghdad University
Treatment of Cutaneous Leishmaniasis by Topical 25% Podophyllin Solution
AG Al-Ghazzi, 2009
Publication Date
Mon Jan 01 2018
Journal Name
International Journal Of Agricultural And Statistical Sciences
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Publication Date
Fri May 18 2018
Journal Name
International Journal Of Simulation: Systems, Science & Technology
(1)
Publication Date
Tue May 01 2018
Journal Name
Antimicrobial Agents And Chemotherapy
Complex Interplay between Sphingolipid and Sterol Metabolism Revealed by Perturbations to the Leishmania Metabolome Caused by Miltefosine
With the World Health Organization reporting over 30,000 deaths and 200,000 to 400,000 new cases annually, visceral leishmaniasis is a serious disease affecting some of the world's poorest people. As drug resistance continues to rise, there is a huge unmet need to improve treatment. Miltefosine remains one of the main treatments for leishmaniasis, yet its mode of action (MoA) is still unknown. Understanding the MoA of this drug and parasite response to treatment could help pave the way for new and more successful treatments for leishmaniasis. A novel method has been devised to study the metabolome and lipidome of
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Publication Date
Fri Jul 29 2022
Journal Name
Journal For Vascular Ultrasound
A Comparative Study of the Right and Left Carotid Arteries in Relation to Age for Patients With Diabetes and Hypertension
Introduction:
Introduction: Age
hypertension
and diabetes can cause significant alterations in arterial structure and function
including
changes in lumen diameter (LD)
intimal-medial thickness (IMT)
flow velocities
and arterial compliance. These are also considered
risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and
IMT has been reported by some researchers
and a difference in the incidence of nonlacunar stroke has been reported between
the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and
left common carotid arteries and internal carotid arteries in patients with hypertension and diabetes for 2 age groups.
Methods: We studied 250 patients with both diabetes and hypertension. Patients were divided into 2 age groups with the
old age group being 56 to 75 years and the young age group 35 to 55 years. The bilateral common carotid and internal carotid
arteries were evaluated with B-mode ultrasound and Doppler examinations. The LD and IMT were measured for both common
carotid arteries
and spectral waveform parameters and indices were recorded for both internal carotid arteries.
Results: The difference in LD between the left and right common carotid arteries for the old age group was 11.64% and for the
young age group was 6.42%
with significant P values of <.05 for both age groups. The difference in IMT between the left and
right common carotid arteries was 18.27% in the old age group compared with 15.38% in the young age group
with significant
P values of <.05. There was a difference in peak systolic velocity between the left and right internal carotid arteries of 4.85%
in the old age group which was not significant
compared with 14.28% in the young age group with a significant P value <.05
whereas the difference in end-diastolic velocity between the left and right internal carotid arteries was not significant for both
age groups. Differences between the right and left internal carotid arteries for resistive index
pulsatility index
and pressure
gradient were significant only in the young age group.
Conclusion: We found significant differences between the right and left common carotid and internal carotid arteries in
patients with diabetes and hypertension which were more prominent in the young age group. Values for common carotid IMT
and LD were significantly higher in the left common carotid artery versus the right common carotid artery in both age groups.
Differences between the 2 carotid sides may be attributed to anatomic variations in the common carotid artery origins which
lead to differences in stress between the 2 sides
Age, hypertension, and diabetes can cause significant alterations in arterial structure and function, including changes in lumen diameter (LD), intimal-medial thickness (IMT), flow velocities, and arterial compliance. These are also considered risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and IMT has been reported by some researchers, and a difference in the incidence of nonlacunar stroke has been reported between the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and left common carotid arteries and internal carotid arteries in patient
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(5)
Publication Date
Mon Apr 06 2020
Journal Name
Asian Journal Of Civil Engineering
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