Total no. of patient (100) stool samples were collected, during the period from February to the end of May of 2008, for children under two years old suffering from non-bloody and bloody diarrhea at (Children Welfare Teaching Hospital) in Baghdad. The study evaluates the relationship between etiological agent of diarrhea and sex, age group, type of feeding, presence of blood in stool of the patients. All samples were examined microscopically to identify parasitic agent and serological test for Rotavirus to identify viral infection, also biochemical and serological tested for specimen's culture on different culture media and antibiotic sensitivity test. Results show from 100 cases 64] represents the etiological agent of diarrhea and the most common of this agent was Rotavirus represent (37.5 %), respectively then Entamoeba histolytica (21.9 %), other agents were include Proteus (12.5 %), Enteropathogenic E.coli (10.9 %), Citrobacter braakii (7.8 %), Salmonella typhi (6.3 %), and Giardia lamblia (3.1 %). The remaining 36 isolates represent of unknown etiological agent for another's pathogen.The prevalence ratio of infection in male (75.0 %) was more than in female (25.0 %), in the first year of age especially in the age group (0-6) months (42.2 %). children depending on artificial feeding represent about (57.8 %) higher natural and mixed feeding, the bloody diarrhea associated with Entamoeba histolytica (57.1 %) in contrast to some etiological agent of non-bloody diarrhea. Eleven types of antibiotics were used for sensitivity test show all serotype of Enteropathogenic E.coli and Salmonella typhi are sensitive to Imipenem and Ciprofloxacin. The predominant serotypes of Enteropathogenic E.coli which represent serotype O111 and serotype O125 these strains show resistance to Cefotaxime (CTX), Trimethoprim-sulfamethaxazole (SXT), Ampicillin (AM), Metronidazole (MET), Cefoperazone (CEP), Cefixime (CFM), also the serotype O111 resistance to Gentamicin (CN) represent (45.0 %), while the most resistance of Salmonella was to Amikacin (100.0 %). This may reflect the fact that the increased resistance in older children and adult may be associated with the development of immunity or the loss of receptors for some specific adhesion. In Iraq Rotavirus infection is estimated to account for (10-29 %) in early childhood, While in neighboring countries the rate ranges between (19-46 %). The study show infected males more than female and the highest diarrheal infection was caused by Rotavirus, the Imipenem and Ciprofloxacin antibiotic was the most effective one against pathogenic strains of Enteropathogenic E.coli and Salmonella typhi while all isolates were resistant to Trimethoprim-Sulfamethaxazole, Ampicillin, Metronidazole.
Hematological malignancies are important diseases that need more powerful therapeutics. Even with current targeting therapies, such as rituximab and other chemotherapeutic agents, there is a need to develop new treatment strategies. Combination therapy seems the best option to target the tumor cells by different mechanisms. Virotherapy is a very promising treatment modality, as it is selective, safe, and causes cancer destruction. The Iraqi strain of Newcastle disease virus (NDV) has proved to be effective both in vitro and in vivo. In the current work, we tested its ability on anti-hematological tumors and enhanced current treatments with combination therapy, and studied this combination using Chou–Talalay analysis. p53 concentration was
... Show MoreBackground: Chronic kidney disease is a worldwide health problem, with adverse outcomes of cardiovascular disease and premature death, can be divided into five stages, depending on how severe the damage is to the kidneys, or the level of decrease in kidney function, the final stage of chronic kidney disease is called end-stage renal disease, salivary immunoglobulin A is the main immunoglobulin found in mucous secretions, including tears, saliva, colostrum and secretions from the genitourinary tract gastrointestinal tract, prostate and respiratory epithelium . It is also found in small amounts in blood.This study aimedto measuresalivary flow rate and salivaryimmunoglobulin Alevels in chronic kidney disease patients on hemodialysis treatment
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It is considered as one of the statistical methods used to describe and estimate the relationship between randomness (Y) and explanatory variables (X). The second is the homogeneity of the variance, in which the dependent variable is a binary response takes two values (One when a specific event occurred and zero when that event did not happen) such as (injured and uninjured, married and unmarried) and that a large number of explanatory variables led to the emergence of the problem of linear multiplicity that makes the estimates inaccurate, and the method of greatest possibility and the method of declination of the letter was used in estimating A double-response logistic regression model by adopting the Jackna
... Show MoreObjective To investigate the accuracy of gingival crevicular fluid (GCF) E-cadherin and total antioxidant capacity (TAC) to discriminate periodontal health from disease. Subjects and Methods GCF samples were collected from participants with periodontal health (control), gingivitis, and periodontitis (n = 25 each group). The latter group was further subdivided according to stage (S) and grade. Periodontal parameters were recorded then levels of biomarkers were assayed using ELISA and antioxidant status by use of the Total Antioxidant Capacity Assay for E-cadherin and TAC, respectively. Results All periodontal parameters were significantly higher in periodontally diseased groups than controls. The GCF E-cadherin significantly increased
... Show MoreBackground/Objectives: The purpose of this study was to classify Alzheimer’s disease (AD) patients from Normal Control (NC) patients using Magnetic Resonance Imaging (MRI). Methods/Statistical analysis: The performance evolution is carried out for 346 MR images from Alzheimer's Neuroimaging Initiative (ADNI) dataset. The classifier Deep Belief Network (DBN) is used for the function of classification. The network is trained using a sample training set, and the weights produced are then used to check the system's recognition capability. Findings: As a result, this paper presented a novel method of automated classification system for AD determination. The suggested method offers good performance of the experiments carried out show that the
... Show MoreAs the leading cause of dementia, Alzheimer's disease (AD) is among the most prevalent progressive neurodegenerative diseases globally. The primary indicators of Alzheimer's disease consist of progressive memory impairment together with intellectual decline. Dementia cases from Alzheimer's disease constitute 50-60% of the total, while projections show these numbers will increase from 55 to 151 million by 2050. The development and enhancement of innovative therapeutic agents represent an absolute necessity for treating this medical condition.In this review, we will focus on synthesizing new promising therapeutic agents by many researchers that may improve some of the drawbacks of available drugs that only gave supportive care to Alzheimer's
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It is considered as one of the statistical methods used to describe and estimate the relationship between randomness (Y) and explanatory variables (X). The second is the homogeneity of the variance, in which the dependent variable is a binary response takes two values (One when a specific event occurred and zero when that event did not happen) such as (injured and uninjured, married and unmarried) and that a large number of explanatory variables led to the emergence of the problem of linear multiplicity that makes the estimates inaccurate, and the method of greatest possibility and the method of declination of the letter was used in estimating A double-response logistic regression model by adopting the Jackna
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