خلفية البحث: مع دخول جائحة COVID-19 عامه الثالث ، من الواضح أن آثاره تمتد إلى ما بعد الجهاز التنفسي وهي مهمة سريريًا. قد يكون لهذه العواقب أيضًا تأثير على الصحة ونوعية الحياة. ربما يكون ثلث النساء قد عانين من تغيرات عابرة في أنماط الدورة الشهرية نتيجة للضغوط المرتبطة بوباء COVID-19. وقد يكون هذا التغيير ناتجًا عن التوتر والقلق. يمكن أن يكون عدم انتظام الدورة الشهرية أو غيابها مؤشرًا على انخفاض الخصوبة ، والذي يمكن أن يرتبط بحد ذاته بعدد من الحالات المزمنة ،و قد يتسبب النزيف الحاد في الإصابة بفقر الدم وله تأثير سلبي كبير على نوعية الحياة ويشكل عبئًا اجتماعيًا واقتصاديًا ضخمًا على النساء وأسرهن والخدمات الصحية والمجتمع. الاهداف : ان الهدف من هذه الدراسة هو النظر في تأثير عدوى فيروس كورونا على مستوى الهرمونات للمرأة (استراديول (E2) ، البرولاكتين (PRL) ، الهرمون المنبه للجريب (FSH) ، والهرمون اللوتيني (LH)) ، وكذلك الحالات النزيف الغزير الذي يحدث عند النساء العراقيات قبل انقطاع الطمث المصابات بفيروس كورونا لمدة شهرين إلى ستة أشهر على الأقل. المرضى وطرق العمل/ المواد وطرق العمل: اجريت هذه الدراسة البحثية في مدينة بغداد الطبية (العيادة الاستشارية) ، من تشرين الثاني (نوفمبر) 2021 إلى نيسان (أبريل) 2022. وشملت الدراسة 100 امرأة متزوجة في سن الإنجاب تتراوح أعمارهن بين 18 و 40 سنة. تم تقسيم عينة الدراسة إلى مجموعتين ، المجموعة الاولى 50 امرأة في سن الإنجاب مصابات بالنزيف الحاد بعد الإصابة بـ COVID-19 م لمدة أربعة أشهر على الأقل ، و 50 امرأة غير مصابات بالفيروس التاجي. النتائج: أظهرت نتائج هذه الدراسة ، بمقارنة متوسط ± SD للمجموعتين ، أن مستويات LH كانت ذات دلالة إحصائية عالية لدى النساء اللواتي عانين من نزيف حاد بعد عدوى COVID-19 مقارنة بالنساء غير المصابات بـ COVID-19 ، مع قيمة p 0.000. لم تكن هناك فروق ذات دلالة إحصائية في مستويات FSH بين المجموعتين. كانت مستويات PRL أعلى من الناحية الإحصائية بالنسبة للنساء اللائي عانين من نزيف كبير بعد الإصابة بـ COVID-19 مقارنة بالنساء غير المصابات بـ COVID-19 ، بقيمة p 0.003. كان E2 ذو دلالة إحصائية عالية مقارنة بالنساء اللائي عانين من نزيف مفرط بعد عدوى COVID-19 مقارنة بالنساء غير المصابات. الاستنتاجات: تشير نتائج هذه الدراسة إلى أن النساء بعد الاصابة بـ COVID-19 قد يكون لهن تأثير على أنماط الدورة الشهرية ، ولكن هذا التأثير كان مؤقتًا ويمكن أن يكون بسبب التوتر والقلق الذي يؤثر على HPA ومبايض النساء. قد يؤدي ذلك إلى اضطراب وظائف الجهاز التناسلي الأنثوي ، حيث تظهر مستويات مرتفعة من هرمونات الغدد التناسلية مثل LH و PRL و E2 وأحيانًا تؤدي إلى حالة نزيف حاد بعد الإصابة بفيروس كورونا.
Polycystic ovary syndrome (PCOS) referring to a syndrome that is recognized as a life-course disease and has both metabolic and reproductive signs; main pathophysiological cause includes insulin resistance, hyperandrogenism, and oxidative stress state. The study aimed to assess the impact of combining Myoinositol and Metformin, the main insulin-sensitizing drugs, on improving clinical, metabolic, and hormonal parameters in females with PCOS. A clinical trial that was prospective, randomized, and comparative on 54 patients (aged 18-40 y) are divided into three groups: group1 patients allocated to receive Myo-inositol(4g), group2 patients assigned to receive Metformin(1g) and group3 patients assigned to receive Myo-inositol(4g) + Metformin
... Show MoreCervical cancer is the third most common cancer in women worldwide, and it has the fourth highest mortality rate among cancers in women. The present study aimed to reveal the impact of age factor in cervical abnormalities and cancers incidence in some Iraqi married women. 150 scraping cervical cells samples were collected from the women clinically diagnosed with cervical abnormalities and cancer who were divided into two groups; the first group included the women with abnormal pap smear which revealed 13.33% of women were less than 30 years and followed by 66.66% of women whose age between 30-50 years and 20% of them were more than 50 years old. While the second group iclude the women with normal Pap smear (Healthy women) which revealed tha
... Show MoreBackground: Chronic hepatitis B virus (HBV) infection is a common health problem that has a worldwide distribution. Apart from the direct effect of the virus on the liver, there are many extrahepatic manifestations among which the probable effect on bone turnover associated with low bone mineral density (BMD). Objectives: This study aimed to determine the association between treated and untreated chronic HBV infection with BMD. Methods: This is a cross-sectional study which included a total of 48 patients with chronic HBV (28 patients treated with tenofovir-disoproxil-fumarate [TDF] antiviral drug and 20 patients have not yet started treatment). Other age- and sex-matched 30 apparently healthy individuals were recruited to represent the hea
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The pressures of life have become a tangible phenomenon in all societies in varying degrees. This disparity determines several factors, including the nature of societies, the level of their urbanization, the intensity of interaction, the intensity of conflict, and the increasing rate of change in those societies. many people name The modern era in which we live the “era of pressures", where one of the most important of these changes is the “new Coronavirus 19-COVID”, which has spread widely throughout the world, as the pandemic, has affected all aspects of daily life, including the educational and academic process, academic activities have been suspended in universities, which caused sudden change
... Show MoreWe examine 10 hypothetical patients suffering from some of the symptoms of COVID 19 (modified) using topological concepts on topological spaces created from equality and similarity interactions and our information system. This is determined by the degree of accuracy obtained by weighing the value of the lower and upper figures. In practice, this approach has become clearer.
Three groups of subjects have been divided (25/group): healthy normotensive non-pregnant women (Group A), normal normotensive pregnant women (Group B), and women with preeclampsia (Group C).The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin , creatinine , blood urea nitrogen, triglyceride , total cholesterol and glucose have been estimated in all subjects. All measured parameters were determined by spectrophotometric analysis. The results showed a significant(P<0.05) increase in serum ALT, AST, blood urea nitrogen, triglyceride and total cholesterol levels in group B as compared to group A. However creatinine, total bilirubin and glucose levels did not show any statistical significant alt
... Show MoreThe beginning of COVID-19 in Wuhan, China in late December 2019 and its worldwide transmission has led the World Health Organization to formally address the pandemic. The pandemic has imposed influential impacts on different environmental, economic, social, health, and living aspects. Publishing in scholastic journals was not immune from these impacts.
Automated clinical decision support system (CDSS) acts as new paradigm in medical services today. CDSSs are utilized to increment specialists (doctors) in their perplexing decision-making. Along these lines, a reasonable decision support system is built up dependent on doctors' knowledge and data mining derivation framework so as to help with the interest the board in the medical care gracefully to control the Corona Virus Disease (COVID-19) virus pandemic and, generally, to determine the class of infection and to provide a suitable protocol treatment depending on the symptoms of patient. Firstly, it needs to determine the three early symptoms of COVID-19 pandemic criteria (fever, tiredness, dry cough and breat
... Show MoreBACKGROUND: Coronavirus current pandemic (COVID-19) is the striking subject worldwide hitting countries in an unexplained non-universal pattern. Bacillus Calmette–Guérin (BCG) vaccine was an adopted recent justification depending on its non-specific immune activation properties. Still the problem of post-vaccine short duration of protection needs to be solved. The same protective mechanism was identified in active or latent tuberculosis (TB). For each single patient of active TB, there are about nine cases of asymptomatic latent TB apparently normal individuals living within the community without restrictions carrying benefits of immune activation and involved in re-infection cycles in an excellent example of repeated immunity tr
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