In the present paper, three reliable iterative methods are given and implemented to solve the 1D, 2D and 3D Fisher’s equation. Daftardar-Jafari method (DJM), Temimi-Ansari method (TAM) and Banach contraction method (BCM) are applied to get the exact and numerical solutions for Fisher's equations. The reliable iterative methods are characterized by many advantages, such as being free of derivatives, overcoming the difficulty arising when calculating the Adomian polynomial boundaries to deal with nonlinear terms in the Adomian decomposition method (ADM), does not request to calculate Lagrange multiplier as in the Variational iteration method (VIM) and there is no need to create a homotopy like in the Homotopy perturbation method (HPM), or any assumptions to deal with the nonlinear term. The obtained solutions are in recursive sequence forms which can be used to achieve the closed or approximate form of the solutions. Also, the fixed point theorem was presented to assess the convergence of the proposed methods. Several examples of 1D, 2D and 3D problems are solved either analytically or numerically, where the efficiency of the numerical solution has been verified by evaluating the absolute error and the maximum error remainder to show the accuracy and efficiency of the proposed methods. The results reveal that the proposed iterative methods are effective, reliable, time saver and applicable for solving the problems and can be proposed to solve other nonlinear problems. All the iterative process in this work implemented in MATHEMATICA®12. ABSTRAK: Kajian ini berkenaan tiga kaedah berulang boleh percaya diberikan dan dilaksanakan bagi menyelesaikan 1D, 2D dan 3D persamaan Fisher. Kaedah Daftardar-Jafari (DJM), kaedah Temimi-Ansari (TAM) dan kaedah pengecutan Banach (BCM) digunakan bagi mendapatkan penyelesaian numerik dan tepat bagi persamaan Fisher. Kaedah berulang boleh percaya di kategorikan dengan pelbagai faedah, seperti bebas daripada terbitan, mengatasi masalah-masalah yang timbul apabila sempadan polinomial bagi mengurus kata tak linear dalam kaedah penguraian Adomian (ADM), tidak memerlukan kiraan pekali Lagrange sebagai kaedah berulang Variasi (VIM) dan tidak perlu bagi membuat homotopi sebagaimana dalam kaedah gangguan Homotopi (HPM), atau mana-mana anggapan bagi mengurus kata tak linear. Penyelesaian yang didapati dalam bentuk urutan berulang di mana ianya boleh digunakan bagi mencapai penyelesaian tepat atau hampiran. Juga, teorem titik tetap dibentangkan bagi menaksir kaedah bentuk hampiran. Pelbagai contoh seperti masalah 1D, 2D dan 3D diselesaikan samada secara analitik atau numerik, di mana kecekapan penyelesaian numerik telah ditentu sahkan dengan menilai ralat mutlak dan baki ralat maksimum (MER) bagi menentukan ketepatan dan kecekapan kaedah yang dicadangkan. Dapatan kajian menunjukkan kaedah berulang yang dicadangkan adalah berkesan, boleh percaya, jimat masa dan boleh guna bagi menyelesaikan masalah dan boleh dicadangkan menyelesaikan masalah tak linear lain. Semua proses berulang dalam kerja ini menggunakan MATHEMATICA®12.
Abstract Background: Acute myeloid leukemia (AML) results from sequential genetic alterations in a normal hematopoietic stem cell or its progenitors giving rise to an autonomous clone that dominates the bone marrow leading to marrow failure. MicroRNAs are short non-coding nucleic acid sequences that regulate post-transcriptional gene expression by base-pairing with their target mRNAs. MiRNAs can be secreted into extracellular fluids and carried to target cells by vesicles or bound to proteins. Intracellular and circulating miRNAs are believed to be useful markers in the diagnosis, prognosis, and treatment of various cancers. Practically, circulating miRNAs are more stable at room temperatures and extreme conditions. Purpose: This study aim
... Show MoreThe prostaglandins inside inflamed tissues are produced by cyclooxygenase-2 (COX-2), making it an important target for improving anti-inflammatory medications over a long period. Adverse effects have been related to the traditional usage of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of inflammation, mainly centered around gastrointestinal (GI) complications. The current research involves the creation of a virtual library of innovative molecules showing similar drug properties via a structure-based drug design. A library that includes five novel derivatives of Diclofenac was designed. Subsequently, molecular docking through the Glide module and determining the binding free energy implementing the P
... Show MoreThe research tackles the potential challenged faced the translator when dealing with the literal translation of nowadays political terms in media. Despite the universal complexity of translating political jargon, adopting literal translation introduces an added layer of intricacy. The primary aim of literal translation is to maintain faithfulness to the original text, irrespective of whether it is in English or Arabic. However, this method presents several challenges within the linguistic and cultural dimensions. Drawing upon scholarly sources, this article expounds upon the multifaceted issues that emerge from the verbatim translation of political terms from English into Arabic. These problems include political culture, language differenc
... Show MoreThe development of new cephalosporins with improved activity against resistant microbes, such as, MRSA (methicillin resistant Staph. aureus), P. aeruginosa, is of high potential. Chemical synthesis of two new series of thiadiazole linked to cysteine (series 1) and cephalosporins containing thiadiazole linked to cysteine through disulfide bond (series 2) were achieved. The chemical structures of the synthesized compounds were confirmed using spectral (FT-IR, 1H-NMR) and elemental microanalysis. The incorporation of privileged chemical moieties, such as, thiadiazole, Schiff base, cysteine and sulfonamide, has been found to have great contribution to the antimicrobial activities. Compounds of series 1 (1
... Show MoreThis study was conducted to delineate diversity and species composition of non-diatoms planktonic algae in Hoor- Al- Azime marshes, Iran. The samples were collected from four sites at monthly basis from April 2011 to March 2012. A total 88 taxa were identified, out of which (40 taxa, 45.45%) belonging to Cyanophyta followed by Chlorophyta (29 taxa, 32.96%), Euglenophyta (18 taxa, 20.45%) and (1 taxa, 1.14%) of Dinophyta recorded. Comparing species richness (65 taxa, 34.76%) at Shat- Ali (St4) was the highest and the lowest (34 taxa, 18.18%) was observed at Rafi (St2). Species occurrence was associated with temperature where in summer (66 taxa) and (25 taxa) encountered winter. The phy
Background: The synthesis and characterization of novel liquid crystalline compounds have garnered signi|cant attention due to their potential applications in biomedical sciences, including drug delivery systems, biosensing, and diagnostic tools. This study focuses on synthesizing and characterizing new thiazolothiadiazole-based liquid crystals and evaluating their mesophase properties. Methods: A series of novel compounds containing 5H-thiazolo[4,3−b][1,3,4] thiadiazole units were synthesized via multi-step chemical reactions. The synthesis involved the reaction of chloroethyl acetate with 4−hydroxybenzaldehyde to yield an aldehyde intermediate, followed by subsequent transformations using hydrazine hydrate, ethylacetoacetate, and 1,2
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