ABSTRACT: BACKGROUND: Estrogens has traditionally been known as the female hormone, but this idea has been challenged in early 1990’s and an essential physiological role for estrogen in male fertility was identified. Phytoestrogens are naturally occurring non-steroidal plant chemicals that can act like the female hormone estrogen. The herbs ( anise alfalfa and vervain ) chosen in this study contain phytoestrogens. OBJECTIVE: Previous studies demonstrated controversy of the effects of phytoestrogens on the rat testes .Hence, the present investigation was undertaken to investigate the influence of typical dose of herbs containing phytoestrogen on the rat testis. MATERIALS AND METHODS: Twenty-four apparently normal mature male rats were divided into four groups of 6 animals each. The first "control" group received only 4ml of distilled water as a placebo. The second group received 40mg/kg of anise seed; the third group received 53.3 mg/kg of dried herb of vervain and the fourth group received 400 mg /kg of alfalfa seeds. All experimental groups received the doses through orogastric tube daily for fourteen days. Testicular histology was evaluated by light and enzyme histochemistry. Plasma FSH and testosterone concentrations were taken to support our results. RESULTS: Histological examination of anise, alfalfa and vervain – treated groups showed an increase in the height of germinal epithelia. There was marked lipoprotein lipase activity in the whole of the interstitial tissue which is more in amount in experimental groups than that in control group. Acid phosphatase granules were infiltered the seminiferous epithelia mildly in control group , moderately in anise and vervain groups and markedly in alfalfa group. The number of interstitial cells showing marked acid phosphatase activity was higher in all experimental groups than that in control group. Alkaline phosphatase exhibited intense activity in the boundary tissue of the seminiferous tubules in testes of control and experimental groups but it appeared thicker in the latter. CONCLUSION: The low dose and short duration of treatment used in our study made these phytoestrogen – containing herbs to have a stimulatory effect on leydig cell steroidogenesis. This study also demonstrated that aniseed being the most potent of the three herbs followed by alfalfa in stimulating testosterone synthesis. This is possibly attributed to the coumarin constituent of aniseed and alfalfa. KEY WORDS: phytoestrogen-containing herbs, testis, acid phosphatase, alkaline phosphatase, lipoprotein lipase
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Abstract: Recombinant human bone morphogenetic protein-2 (rhBMP-2) and platelet-rich fibrin (PRF) bioactive materials have been used to enhance healing and improve dental implant stability. This study aimed to compare the effect of rhBMP-2 and PRF bioactive materials on dental implant stability at different intervals and to evaluate the correlation of implant length and diameter with implant stability. Two bioactive materials were compared to evaluate their effect on dental implant stability. A total of 32 patients (102 dental implants) were divided into 3 groups: 24 dental implants with bone morphogenetic protein (BMP), 27 dental implants with PRF, and 51 dental implants without BMP or PRF (control group). Data were statistically analyzed
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The structural, optical properties of copper oxide thin films ( CuO) thin films which have been prepared by thermal oxidation with exist air once and oxygen another have been studied. Structural analysis results of Cu thin films demonstrate that the single phase of Cu with high a crystalline structure with a preferred orientation (111). X-ray diffraction results confirm the formation of pure (CuO) phase in both methods of preparation. The optical constant are investigated and calculated such as absorption coefficient, refractive index, extinction coefficient and the dielectric constants for the wavelengths in the range (300-1100) nm.
European Chemical Bulletin (ISSN 2063-5346) is a peer-reviewed journal that publishes original research papers, short communications, and review articles in all areas of chemistry. European Chemical Bulletin has eight sections, namely
Is the subject of Facebook of more topics that aroused interest and that it provides the features and services that allows users to direct communication and interaction and dialogue with others, and deals with the subject of research the use of Facebook and its effects left by the social relations, as the field study was conducted on a sample of 130 students from students Baghdad University of males and females in the Faculty of Political Science and Agriculture, Science and Education, Girls, and limited the sample to Facebook users exclusively to test the study hypotheses and relationships connectivity, and the results revealed the presence of a significant impact of Facebook in th
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The Back-Propagation (BP) is the best known and widely used learning algorithm in training multiple neural network. A vast variety of improvements to BP algorithm have been proposed since ninety’s. in this paper, the effects of changing the number of hidden neurons and activation equation are investigated. According to the simulation results, the convergence speed have been improved and become much faster by the previous two modifications on the BP algorithm.
The study was conducted to determine the effect Toxoplasma gondii and the efficacy of azithromycin and garlic tablets on the treatment of acute murine toxoplasmosis and observe the histopathological changes due to infection. 60 Albino mice were divided into six groups, and their survival rate, pathology, bioassay trial and immunofluorescence were observed. Results revealed that azithromycin (250 mg/kg/day) given to infected mice increased the survival rate (90% on day 7 PI) and decreased the histopathological changes when compared with the control groups. Garlic tablets (500 mg/kg/day) had lesser effect on infected mice, and the survival rate (40% at days 6 and 7 PI) was lower than the groups treated with azithromycin. The group treated wit
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