ervical cancer is one of the most frequently diag nosed malignancies representing the fourth leading cause of cancer-related death in females’ worldwide, with approximately 500,000 new cases diagnosed and 280,000 deaths occurring each year. Mxi1, an antagonist of c-Myc, maps to human chromosome 10q24-q25, a region altered in a substantial fraction of prostate tumors, in prostate cancer, where a high frequency of loss and mutation of the MXI1 gene has been reported. The aim of present study was to find out the possible association of exon deletion of MXI1 gene with incidence of cervical abnormalities and cancers in some Iraqi married women. The present study include collection of 120 scraping cervical cells samples from women clinically diagnosed with cervical abnormalities and cancer, and 30 scraping cervical cells samples from apparently healthy women and all these samples were submitted for cytological and histopathological examination. DNA was extracted from all these samples, and then the singleplex PCR was performed with primers targeted the exon1, 2, 3, 4, 5 and 6 of MXI1 gene. The results of cytological examination showed that 30 (25%), 21 (17.5%), 15 (12.5%), 11 (9.16%), 2 (1.66%), 1 (0.83%), 22 (18.33%) and 18 (15%) out of 120 scraping cervical cells samples were detected for ASCUS, LSIL, HSIL, SCC, AGUS, cervicitis, and cervicitis with squamous metaplatia, respectively. Also the results of histopathological examination showed that 32 (26.66%), 19 (15.83%), 17 (14.16%), 11 (9.16%), 1 (0.83%), 22 (18.33%) and 18 (15%) out of scraping cervical cells samples were detected for CINI, CINII, CINIII, SCC
ABSTRACT Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women in their reproductive age.It is characterized by anovulation or oligo-ovulation and hyperandrogensim.Androgen excess is the central defect in polycystic ovary syndrome. It is a complex disorder affects general health in addition to oral health.This study aimed to assess the gingival health status among a group of women with polycystic ovary syndrome as well as to estimate the levels of salivaryfree testosterone in unstimulated saliva in relation to gingival health condition. Materials and methods: Sixty two women with an age range 20-25 years old and with a body mass index range18.5-24.9 (normal weight) were included in this s
... Show MoreObjectives: to assess Socio Demographic, Reproductive Characteristics, and healthy dietary behaviors. among women with osteoporosis . To determine the relationship between the socio demographic characteristics, reproductive data and dietary related behaviors. Methodology: A descriptive analytic design was conducted on Non- Probability ( purposive sample) of (90) women who have suffering from osteoporosis attend to (DEXADual-Energy X-ray Absorptiometry) unit in Merjan Teaching Hospital in Hilla City. A questionnaire has been used as a tool of data collection and consists of three part ;including : Soci
Polycystic ovary syndrome(PCOS) is a heterogeneous disorder of uncertain etiology , it is the most common endocrinopathy in women and most common cause of anovulatery infertility ,characterized by chronic anovulation and hyperandrogenemia .The present study was designed to investigate the effect of silymarin which is known to have antioxidant and insulin sensitivity effects on the levels of glucose, insulin ,testosterone ,leutinizing hormone(LH) and progesterone .Ovulation rate and Homeostasis Model Assessment of insulin Resistance (HOMA) ratio were determined .A 3-months of treatment were conducted in 60 PCOS patients in three well-matched groups .The first one (n=20),received silymarin(750mg/day) .The second group received
... Show MoreAbnormalities in the Lipid and lipoprotein levels are common in the general population and are considered as very important risk- factors for cardiovascular disease .In this context the effect of cholesterol, which is one of the most clinically relevant lipids is very important. Aim of the present study was to determine the levels of GLP-1 and GPCR in non- diabetic dyslipidaemic patients and compare the results with the control group, which may be used as a novel biomarker to predict heart disease in these patients. The study was also aimed to find the relationship between GLP-1 and GPCR with lipid profile and glucagon in the patient group. The study involved 90 non-diabetic dyslipidaemia patients, with 90 healthy controls. The subjects wer
... Show MoreZM Al-Bahrani, Medico Legal Update, 2021
Background:-Atherosclerosis is a systemic disease that often affects multiple vascular distributions in a single patient. The increased prevalence of renal artery stenosis in association with coronary artery disease has been well documented.
Objectives:-To examine in detail the prevalence of renal artery stenosis in patients undergoing cardiac catheterization for suspected coronary artery disease.
Patients &methods:-Between April 2010 and February 2011, two hundred patients underwent coronary and renal angiography at the same session in Ibn Al-bitar Hospital for Cardiac Surgery. Clinical and procedural data for patients undergoing renal angiography were prospectively collected and entered into database specially designed for th
Background: Genetic factors play an important role in susceptibility to Guillain Barre' syndrome. Human leukocyte antigen (HLA) as part of immune system has a role in the disease process.Aim of the study: to assess the relationship between HLA-A alleles with Guillain Barre' syndrome (GBS) compared with a healthy control group using PCR-SSOP method.Type of the study: Cross-sectional study.Patients and methods:Patient's group consisted of 30 Iraqi Arab Muslims patients with Guillain Barre' syndrome that consulted the Neurological department in Neurosciences Hospital between January-2013 to January- 2014 were genotyped for HLA-A alleles. A control group consisted of 30 healthy volunteers among the staff of AL-Kindi College of Medicine that
... Show MoreBackground: Obesity and diabetes mellitus are the common health problems,and obesity is common cause of the insulin resistance. Aim of studv: Aim of the study is to find any correlation between obesity (insulin resistance) and type I diabetes in children. Patients and methods: This study included (40) children with type I diabetes, in addition to (40) children as control.The age of all studied groups ranged from (8-18) years.This study was attemted from Ibn AlBalady Hospital during from 20 August to 9 Novembar,2008. The subjects wrer divided into (4) groups according to their BMI:- * Obese children,diabetes,n=2O,BMI>30. * Non obese children, diabetes, n=20,BMI<25. Obese children, non diabetes, n=20,BMI>30. * Non obese children,non diabetes
... Show MoreThis study was established to discover and determine multidrug-resistant Escherichia coli and Klebsiella pneumoniae from women suffering urinary tract infections, specifically in Mosul city. A total of 62 E. coli and 32 K. pneumoniae bacterial isolates were considered for this study. All isolates were characterized using standard bacterial culture methods, including culture on MacConkey agar, Eosin Methylene Blue agar and biochemical tests. Also antibiotic sensitivity test using standard disc method for different antibiotics and also special discs to detect ESBL activity were carried out, in addition to PCR as molecular identification tool. The results showed that most isolated E. coli
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