Background: Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women of
reproductive age with primary features of infertility, menstrual irregularity, and clinical or biochemical
evidence of hyperandrogenism (hirsutism, acne and high androgen level). Vitamin D has a role in the
development of metabolic and endocrine abnormalities in PCOS mediated by insulin resistance.
Objective: Measure serum 25-hydroxy vitamin D levels in women with polycystic ovary syndrome and
compare their levels with age and body mass index matched healthy controls. Also, assess the
correlation between insulin resistance and 25-hydroxy vitamin D among women with PCOS.
Subjects and Methods: Eighty eight women were involved in this st
Background: Nephrotic syndrome is an immune mediated disorder of the kidney associated with T cell dysfunction and secondary disturbance of B cell with changes in levels of immunoglobulin.
Objectives: The objectives of this study were to compare immunoglobulin levels in children with nephrotic syndrome in relapse and healthy children, and to assess relationship between the degree of albuminuria and the mean concentrations of immunoglobulin.
Methods: We studied 60 children with nephrotic syndrome during January 2008 to January 2011 in the Pediatric Nephrology consultation clinic, Children Welfare Teaching Hospital –Baghdad Medical Complex –Iraq. Urine protein and blood samples were collected from the 60
The hazardous metabolic effects of treating schizophrenia patients with olanzapine comprise serotonin 2C receptor (5-HT2C) antagonists. Metabolic side effects of antipsychotic drugs, including lipid abnormalities, disturbed glucose metabolism, and weight gain, can have a major impact on treating psychiatric patients. The intent of this study was to investigate whether there is an associated link between the genetic polymorphism at -759C>T in the promoter region of the 5-hydroxytryptamine 2C receptor (HTR2C) gene and the metabolic syndrome driven by olanzapine in schizophrenia patients. A cross-sectional study that involved fifty hospitalized patients with schizophrenia. The patients were split into two groups (metabolic and non-metab
... Show MoreBackground: Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain with associated symptoms including stiffness, fatigue, sleep disturbance and functional impairment. FMS is depicted by chronic pain for at least three months and tender points identified by the American Collage of Rheumatology (ACR). Although several hypotheses have been developed; the cause of FMS is currently unknown.
This study aims to evaluate the contribution of serum apolipoprotein (a) [Apo (a)], leptin, and serum lipid profile to the pathophysiology of FMS.
Subjects & Methods: The study has included 160 patients with FMS with age range (18-72) years and 60 control individuals who were age and sex matc
Several adipokines are produced and secreted from adipose tissue, such as retinol binding protein-4, which triggers metabolic syndromes and insulin resistance. Retinol binding protein-4 transfers vitamin A or retinol in the blood. Higher levels of retinol binding protein-4 are interrelated with progress of metabolic disease, comprising obesity, metabolic syndrome, and type 2 diabetes mellitus. The present study investigates the role of retinol-binding protein-4 levels in type 2 diabetic Iraqi patients with metabolic syndrome. Sixty type 2 diabetic patients aged 40–53 years were examined. Of these 30 patients has metabolic syndrome and 30 without metabolic syndrome. The patients sampled were from the National Diabetes Center/ Mustansiriyah
... Show MoreBackground: Metabolic syndrome (MetS) is a collection of connected cardiovascular risk factors that characterizes the complicated illness. The waist circumference cutoff point fluctuation has so far defined Mets. Objective: This study aimed to determine the cutoff point for WC in healthy Iraqi adults. Methods: This cross-sectional survey establishes the standard value for WC among 300 healthy university students in Wasit city, Iraq. They are aged between 18-25 years. The receiver operator characteristic (ROC) curve was used WC to predict the presence of two or more risk factors for MetS, as defined by IDF. Results: The cutoff level yielding maximum sensitivity and specificity for predicting the presence of multiple risk factors was
... Show MoreThe polycystic ovary syndrome is an endocrine condition. One of the leading causes of female infertility and the most common disorder among women. The work was being carried out on 100 Iraqi women (50 cases confirmed with PCOS and 50 controls). Between October 2019 and March 2020, blood samples were collected from the Advanced Institute of Infertility Diagnosis and Assisted Reproductive Technology at AL-Nahrain University and a private laboratory. ELISA was used to evaluate the biochemical parameters of preptin, FSH, insulin, LH, and CCL 18 in serum samples from the AFIAS-6 (AFIAS Automated Immunoassay System). The findings of the analysis indicate that, as opposed to the control group, values of prolactin (ng/ml), LH (mIU/ml), Preptin (
... Show MoreABSTRACT Background: Polycystic ovarian syndrome (PCOS) is one of the most important reproductive and endocrine disorders in women at reproductive age. It's associated with metabolic disorder, obesity, insulin resistance and oxidative stress chronic periodontitis and PCOS both of them associated with low chronic grade of inflammation. The prevalence of periodontal disease seems to be higher in women with PCOS. Superoxide dismutase enzyme (SOD) is an important circulating marker and protecting enzyme helping the body tissues to get rid of reactive oxygen species (ROS) that damage the tissue. Aim of the study: The aim of this study was to measure and compare the levels of (SOD) among group of chronic periodontitis patients with PCOS, group
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