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Effect of Foeniculum vulgare seed aqueous extract eye drops on selenite induced cataract in rabbits

Cataract is an opacity in the normally transparent focusing lens of the eye which leads to blindness. The aim of current study is to investigate the possible protective and therapeutic effects of aqueous extract of Foeniculum vulgare seed eye drops (0.5%) against selenite induced cataract in rabbits. Aqueous extract of Foeniculum vulgare seed prepared then formulated as eye drops. Sodium selenite used to induce cataract in rabbits' right eye by single intravitreal injection. Thirty-six rabbits included in the study and divided into three equal groups (12 rabbits in each group): healthy control group, Cataract-Induced group and group treated by Foeniculum vulgare seed extract eye drops. Parameters include the score of lens opacity which was determined by using an ophthalmoscope, pupillary response to light, pupil diameter, Corneal sensation, Conjunctival redness, intraocular pressure (IOP) measurement, malondialdehyde (MDA) level in aqueous humor and scanning electron microscope (SEM) image of the eye lens. The results of this study revealed that eye drop of Foeniculum vulgare seed extract was highly significantly reduced the mean of lens opacity score in comparison with cataract-induced group after two weeks of cataract induction (p< 0.01). MDA level of the group treated with Foeniculum vulgare seed extract eye drops was highly significant less than the MDA level of cataract-induced group (p< 0.01). SEM image of rabbit's lens treated by Foeniculum vulgare seed extract eye drops shows normal appearances of the eye lens. in conclusion, eye drops prepared from aqueous extracts of Foeniculum Vulgare seed had protective and …

Publication Date
Tue Mar 28 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Study the Effect of Arabidopsis thaliana Extract on Reducing Blood Glucose Level in Diabetic White Albino Mice

This study was designed to evaluate the effect of aqueous extract of Arabidopsis thaliana seeds on reducing glucose level for white albino mice. Twenty adults mice were used, divided randomly into four groups (five mice per each group). The first group (normal mice) was administrated with 0.1 ml of distilled water as a control, the second group (normal mice) was administrated with 0.1 ml of the plant extract, whereas the third and fourth groups (diabetic mice) were administrated with single dose of alloxan (150 mg/kg of the body weight) to induce diabetes, and the fourth group was administrated with 0.1 ml of the plant extract for 10 days, then blood glucose level was measured for all of the experimental animals (diabetic and no

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Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
Effect of some agronomic technical in morphologe traits, yield compound and oil of rape seed c.v. pactol

A field trial was conducted at Abu-Ghraib research station , Baghdad , Iraq , during the autumn season of 2006. The objectives were to study the effect of nitrogen fertilizer and planting space on the performance of rape seed. A split-plot in a randomized complete of block design with three replications were used. Five levels of nitrogen fertilizer ( 120,160,200,240,280 Kg / ha ) were assigned to main plots, where as planting space in sub-plots. The result obtained confirmed that 280,240 kg / ha nitrogen maximized seed yield 1.830 , 1.773 ton/ha, oil yield,0.843,0.824 ton/ha .Results showed that planting space 30 cm produced the highest seed yield 1.90 ton / ha and oil yield , 0.884 ton / ha . Interactions be

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Publication Date
Sun Mar 02 2008
Journal Name
Baghdad Science Journal
Effect of some agronomic technical in morphologe traits, yield compound and oil of rape seed c.v. pactol

A field trial was conducted at Abu-Ghraib research station , Baghdad , Iraq . The objectives were to study the effect of nitrogen fertilizer and planting space on the performance of rape seed. A split-plot in a randomized complete of block design with three replications were used. Five levels of nitrogen fertilizer ( 120,160,200,240,280 Kg / ha ) were assigned to main plots, where as planting space in sub-plots. The result obtained confirmed that 280,240 kg / ha nitrogen maximized seed yield 1.830 , 1.773 ton/ha, oil yield,0.843,0.824 ton/ha .Results showed that planting space 30 cm produced the highest seed yield 1.90 ton / ha and oil yield , 0.884 ton / ha . Interactions between nitrogen fertilizer and p

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Publication Date
Thu Aug 30 2018
Journal Name
Iraqi Journal Of Science
Study the Effect of Some Methanolic and Aqueous Traditional Plants Extracts on Probiotic Bacteria

Probiotics mean live microorganisms that have beneficial effects on their host’s health. The purpose of this study was to compare aqueous, methanolic of some traditional plant extracts on the viability of dietary probiotic supplementation [a dietary probiotic (Protexin)]. Also, this study was conducted to evaluate the antibacterial effect of various extracts concentrations from 1.25 to 100 mg/ml of Rosmarinus officinal, Glycyrchiza glabra, Hibiscus sabdriffo, Curcuma longa, Citrus auratifolia swingle, Cinnamomum zeylancium, Urtica dioica, Thymus vulgaris, Punica grantum and Zingiber officinal on activities of probiotic bacteria Lactobacillus, Bifidobacterium, Streptococcus thermophillus by determining the minimum inhibitory co

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Publication Date
Thu Apr 20 2023
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
A Protective effect of (Andrographis Paniculata) on 4-Vinylcyclohexene Diepoxide Induced ovarian Toxicity in Female Albino Rats: introduction

Abstract

Background and objective: Protective effect of (Andrographis Paniculata) on 4-Vinylcyclohexene Diepoxide.

Material and methods:A group of 55 female albino rats undergo experiment on the outcome effect of 4-vinylcyclohexene Diepoxide injection for a priod of two weeks, as well as treatment effect of methanolic leaf extract of Andrographis paniculata oral administration for four weeks. Injection  concentrations (160 and 320mg/kg. B.W) also two different doses of treatment (100 and 200mg/kg. B.W) have been applied.

Results:The results on body weight and ovary weight were more evident when higher concentration dose was applied.

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Publication Date
Sat Sep 23 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect Of Solvent Types On Photo Induced Electron Transfer in Methylene Blue dye MB+-- Benzophenone Ketone (ABP) System..

Th   r:ats for the photo induced eleytr-on tra;nsfer reactions in the

Methylen-e blue 'l'vffi+ ·dye· with benzo_phenone (ABP) ketone in variety

solvc;:nts al n:loin tempemtme ha;ve qn calculated . Electron trans_ fer

-rates are large in• }stt:on;gly--'{:'lolaf- solvent and week in-l s.s :polar solvent.

the high values o:E   t±te r.tes a_f electro-n  tr;ans-fer indicate that tite dye

triplet i$ mqre, r activ.e toWard ABP ket-one.

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Publication Date
Mon Apr 01 2024
Journal Name
Latin American Journal Of Pharmacy
The protective effect of iraqi Juniperus oxycedrus plant on acute kidney injury induced by lipopolysaccharide in mice model

Inflammatory control is essential to diminish injury and make renal injury treatment simpler. Proposed therapeutics have primarily targeted pro-inflammatory variables. Juniperus oxycedrus was frequently used to treat a variety of infectious disorders, hyperglycemia, obesity, TB, bronchitis, inflammation, and pneumonia. Juniperus oxycedrus twigs and leaves were defatted with n-hexane using Soxhlet apparatus then the residue of plant material dried and re-extracted sequentially by two different solvents Ethylacetate and methanol. The pro-inflammatory markers IL-1 and iNOS, as well as the potential kidney biomarker KIM-1, TNF-α, and transcription factor NF-KB were measured using the RealTime Quantitative qPCR method. The results showed that J

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Publication Date
Wed Nov 01 2023
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Protective Effect of Daidzein on Ifosfamide-Induced Neurotoxicity Via Improving Some Selected Oxidative Stress Parameters in Male Rats

  In this study, the possible protective effects of daidzein on ifosfamide-induced neurotoxicity in male rats were examined by the determination of changes in selected oxidant–antioxidant markers of male rats’ brain tissue.

Twenty-eight (28) apparently-healthy Wistar male rats weighing (120-150gm) allocated into 4 groups (n=7) were used in this study. Rats orally-administered 1% tween 20 dissolved in distilled water/Control (Group I); rats were orally-administered daidzein suspension (100mg/kg) for 7 days (Group II); rats intraperitoneally-injected with a single dose of ifosfamide (500 mg/kg) (Group III); rats orally-administered for 7 days with the daidzein (100mg/

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Publication Date
Wed Jun 01 2022
Journal Name
Baghdad Science Journal
Antibacterial Activity of Silver Nanoparticles Synthesized by Aqueous Extract of Carthamus oxycantha M.Bieb. Against Antibiotics Resistant Bacteria

Antibiotics resistant bacteria have become a global problem as a result of the unprogrammed use of antibiotics, resulting in bacterial strains resistant to many antibiotics, or to all available antibiotics. Plants are a good source of primary and secondary metabolites that have a major role in reducing silver nitrate to silver nanoparticles (AgNPs). The production of these nanoparticles were carried out by using aqueous extract of Carthamus oxycantha M.Bieb. This can be verified by color change of the reaction solution from yellow to dark brown because of the excitation of the surface plasmon resonance. AgNPs were characterized by UV-Vis spectroscopy, where they recorded the peak at 420 nm. Fourier Transformation-infrared (FTIR)

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Publication Date
Sun Mar 01 2020
Journal Name
Al-mustansiriyah Journal Of Science
Evaluation the activity of Petroselinum crispum aqueous extract as promoter rooting for stem cuttings of some plants

This study was conducted in the botanical garden, Department of biology, College of Science/ Mustansiriyah University in from (15 February to 15 March, 2019) under the natural environmental conditions in the greenhouse in order to evaluate the effectiveness of parsley aqueous extract as a promoter for rooting. The study included the use of aqueous extract of a plant Parsley (Petroselinum crispum) extract was used in concentrations (1.25, 2.5 g / l), compare with IBA in concentration (100 mg / L) with dipping time 24 hour for all treatments. The cutting stems were included Rosmarinus officinalis, Nerium oleander, Olea europaea, Plumeria alba, Hibiscus rosa, Pelargonium graveolens, and Myrtus communis. The following measurements were

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