Introduction: The bacteriological and histopathological study of Raoultella planticola in local rabbits is not presented in previous research. There is no specific information about studying this bacterium in local rabbits. Hypothesis: The present study was based on Bacteriological and Histopathological changes in the trachea and lung of local rabbits after Samples were collected from 50 unhealthy animals that appear to be suffering from respiratory signs. Aim: To study the bacteria that were isolated for the first time from sheep suffering from respiratory infections, and diagnose them through Vitk2. Methods: We injected them into a group of local rabbits and studied the histopathological changes in the trachea and lungs. due to their similar morphological characteristics. Our investigation reported this bacterium as Gram-negative rods. Then used the Vitk2 system to confirm the species of bacteria (93% Probability). Results: The animals showed grossly results (dullness with nasal and ocular discharge, cough). Then euthanasia was performed to sacrifice animals after seven days post-infection. trachea and lung were used in a histopathological study using routine Hematoxylin and Eosin stained. In this study, emphysema and bronchitis often are grouped under the heading of chronic obstructive pulmonary disease (COPD). Conclusion: Raoultella planticola infections is uncertain, and further studies are required. The previous difficulties in the identification of Raoultella planticola may be explained by the introduction of more detailed identification techniques, may explained in the present study. The conclusion of this study also provides that Raoultella planticola causes mild to moderate emphysema in local rabbits.