There are numerous bidirectional interactions between the reproductive system and the liver. Sex steroids regulate metabolic health through signaling effects in both peripheral and central metabolic tissues, including adipose tissue, liver, skeletal muscle, and brain, and have a role in the etiology of structural and functional liver diseases. Blood samples were obtained from 90 healthy women (control group) and 90 women that have hormonal changes (patients’ group). The levels of reproductive hormones (follicle stimulation hormone/FSH, luteinizing hormone/LH, estradiol/E2, progesterone/P4) were measured by using fully automated Cobas E411, whereas those of liver enzymes (alanine transaminase /ALT, aspartate aminotransferase/AST, alkaline phosphatase/ALP) were measured by using fully automated Cobas C111. Levels of copper and ceruloplasmin were measured as well. The results demonstrate a strongly significant positive correlation between the levels of FSH and ALT (r = 0.45, p = 0.0001), FSH and AST (r = 0.48, p = 0.0001), and FSH and ALP (r = 0.303, p = 0.005), LH and ALT (r = 0.301, p = 0.005), LH and AST (r = 0.34, p = 0.001), and LH and ALP (r = 0.307, p = 0.004). The reproductive hormones and liver enzymes had a strong positive correlation. The results demonstrate a correlation between estrogen and copper (r = 0.38, p = 0.0001), as well as a highly significant positive correlation between estrogen and ceruloplasmin (r = 0.43, p = 0.0001) and a positive significant correlation between progesterone and copper (r = 0.26, p = 0.01). These findings are consistent with earlier research that has found a clear link between low estrogen levels in the blood and liver disease in women. These findings imply that an abnormally low level of estrogen may render women more susceptible to developing liver damage.
ervical cancer is one of the most frequently diag nosed malignancies representing the fourth leading cause of cancer-related death in females’ worldwide, with approximately 500,000 new cases diagnosed and 280,000 deaths occurring each year. Mxi1, an antagonist of c-Myc, maps to human chromosome 10q24-q25, a region altered in a substantial fraction of prostate tumors, in prostate cancer, where a high frequency of loss and mutation of the MXI1 gene has been reported. The aim of present study was to find out the possible association of exon deletion of MXI1 gene with incidence of cervical abnormalities and cancers in some Iraqi married women. The present study include collection of 120 scraping cervical cells samples from women clinically di
... Show MorePlacental calcification is an aging process that is increasingly linked to adverse pregnancy outcomes when it occurs prematurely. Vitamin D has immunomodulatory properties and may play a role in placental calcification. This study explored the association between maternal vitamin D, inflammatory cytokines, and placental calcification. A total of 46 pregnant women aged 16–40 years were included in this study. They were divided into four groups: Group 1 (control group; n = 10, without placental calcification), Group 2 (n = 12, Grade 1 placental calcification), Group 3 (n = 12, Grade 2 placental calcification), and Group 4 (n = 12, Grade 3 placental calcification). Serum vitamin D (25(OH)D) and cytokine (TNF-α,
... Show MoreThis research seeks to study the role of proactive leadership as an essential element that helps all federations that lead the wheel of sports, including the Iraqi Handball Federation, so that it builds a correct environment that helps manage the organizational errors that the Handball Federation may fall into, and this in turn helps in early detection of errors and obstacles that may occur. It is likely that the Federation will fall into the process of managing and organizing the Iraqi Handball League, in addition to increasing the clubs’ ability to assist the Iraqi Handball Federation by being proactive so as not to make mistakes. The research community included the administrative bodies of the clubs participating in the Iraqi E
... Show MoreObjective: This study aimed to explore the social and physiological changes that Iraqi women may experience after a hysterectomy. Methods: A cross-sectional study was conducted at the consultation clinic of Al-Elwiya Maternity Teaching Hospital in Baghdad, Iraq. A total of 81 women who underwent emergency hysterectomy and could comprehend and respond to the questionnaire were recruited for this study. A structured, self-administered Arabic-language questionnaire was developed, and it included sociodemographic characteristics, surgical history, preoperative awareness, psychological symptoms, and sexual health impact. Results: The mean age of patients was 43.5
... Show MoreThe objective of this study is to evaluate the level of parathyroid hormone, Co enzyme Q and total antioxidant status in serum’s women with fibromyalgia syndrome firstly, then to demonstrate if these biochemical markers affected by age and obesity.
This study was performed at Rheumatology and Rehabilitation Consultation Unit in Baghdad Teaching Hospital. Venous blood sample were drawn from (59) female with FMS and (30) control (without FMS). The serum was obtained after on standing in order to coagulate then centrifuged. The mean age± SD of FMS group was (42.22±15.34) years and for control was (40.7±18.22) years. Those participants were subdivided into four different groups acc
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