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Assessment of tumor necrosis factor alpha and interleukinـ10 in obese psoriatic patients before and after using apremilast
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Background Psoriasis is one of the most prevalent chronic inflammatory skin conditions; its prevalence ranges from 1 to 3%. Tumor necrosis factor-alpha (TNF-α), a cytokine that enhances inflammation, is overexpressed in synovium and skin plaques in psoriasis. TNF-α plays a critical role in the pathogenesis of psoriasis. IL-10 is the most crucial cytokine for reducing excessive immune responses and decreasing pro-inflammatory reactions in all autoimmune disorders.   Objective To evaluate the effect of Apremilast on ILـ10, TNFـα, and BMI in obese psoriatic patients.   Methods Thirty patients included in this investigative study to measure the concentrations of TNFـα, ILـ10 and BMI, before and after receiving Apremilast. TNFـα and ILـ10 were examined by ELISA technique.   Results The present work found that the concentration of TNF-α before receiving Apremilast was 286.80 pg/ml, and after six months from baseline, it was reduced to 131.08 pg/ml (P<0.01). Also, IL-10 before using Apremilast was 69.28 pg/ml, and after six months of treatment it increased to 112.57 ±7.89, which was statistically significant (P<0.01). There were no statistically significant differences in BMI (P>0.05).   Conclusion Apremilast significantly reduced the inflammatory cytokine TNF-α and increased the anti-inflammatory cytokine IL-10, leading to improvement in psoriasis lesions. It also reduced Body Mass Index in obese psoriatic patients.  

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Publication Date
Wed Apr 30 2025
Journal Name
مجلة دراسات دولية
China-Russia relations after 2013: motives and determinants
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This research aims to identify the reality of Sino-Russian relations after 2013, and to study the most important motives and determinants that affected the nature of these relations. The research was based on the criterion of national interest in interpreting and understanding relations between China and Russia, on the basis that national interest is what determines the state of cooperation and dependence, or the state of competition and difference. The research was based on the hypothesis that Sino-Russian relations after 2013 witnessed many factors and variables, some of which represented motives for strengthening relations between the two countries, and others represented obstacles that limit the level of cooperation and interaction betw

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Publication Date
Sat Dec 01 2018
Journal Name
Political Sciences Journal
power and chinese Abilities development after cold war
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Abstract: This research deals with the developing of power and different abilities (military, security, economy, technology and scientific excellence) The research shows that the excellence of the Chinese economy and its development , had a positive reflection on the other powers and abilities , it means it is a base of development in all fields. The development in power and Chinese military abilities had a clear effect on Chinese strategic creed , and that what the research deals with in some details. The research also deals with developing Chinese nuclear abilities. The research doesn't ignore the security eye that indicates to the protection of the state sovereignty, concentrating on the unity and safety Chinese lands. The res

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Publication Date
Wed Jan 01 2020
Journal Name
Route Educational And Social Science Journal
THE ARAB REGION, REPERCUSSIONS AND SCENARIOS AFTER CORONA
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يمر العالم و المنطقة العربية وضعاً استثنائياً في ظل انتشار فايروس كورونا - 19 - المستحد وما تبعها من تداعيات على جميع الاصعدة في ظل تأثير تلك الجائحة وعلى شتى الاصعدة والمجالات كونها متداخلة ومترابطة معاً، ولاسيما القطاع الاقتصادي المهم الذي ينعكس بصورة مباشرة على المجالات الأخرى، لكون هذا الجانب الاساس الذي يميز المنطقة العربية فهي منطقة غنية بالموارد الطبيعية كالنفط و الغاز الطبيعي، فضلا عن الموقع الاسترا

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Publication Date
Sat Dec 30 2023
Journal Name
Al-kindy College Medical Journal
The Combination of Noninvasive Tests and Fibroscan for the Assessment of Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease
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Background: Most prevalent chronic liver disease in developed and developing nations is non-alcoholic fatty liver disease. From fatty liver, which often has benign, non-progressive clinical history, to non-alcoholic steatohepatitis, a more serious variant of fatty liver that can lead to cirrhosis and end-stage liver disease, non-alcoholic fatty liver disease encompasses broad spectrum of diseases. The gold standard for determining extent of hepatic fibrosis is still liver biopsy; however, number of noninvasive tests have been established to make diagnosis and assess effectiveness of treatment.

Objective: Aim of study was to assess effectiveness of the combination of fibroscan and

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Publication Date
Thu Aug 31 2017
Journal Name
Journal Of Engineering
The Phenomenon of Division and Modification of The Individual Houses in Baghdad after 2003
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The Research deals with the negative phenomena which appeared in the urban scenes of the  Iraqi cities after 2003, particularly trespassing the architectural design of the urban Individual houses.  Many academic researchers , critics, and cultural circles, drawn attention to the impact of  political and cultural variable change on such phenomena  without detailed  analysis . The research problem  is set according to central questions : If the phenomena is the trespass , whatare the sides which are being trespassed  in the division of the individual house? , If the diagnosis of the phenomena denotes perceived repetition of the cases , So what's size of this transposes on the architectural design of the individual house? , and

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Publication Date
Thu Aug 31 2017
Journal Name
Journal Of Engineering
The Phenomenon of Division and Modification of The Individual Houses in Baghdad after 2003
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The Research deals with the negative phenomena which appeared in the urban scenes of the  Iraqi cities after 2003, particularly trespassing the architectural design of the urban Individual houses.  Many academic researchers , critics, and cultural circles, drawn attention to the impact of  political and cultural variable change on such phenomena  without detailed  analysis . The research problem  is set according to central questions : If the phenomena is the trespass , what
are the sides which are being trespassed  in the division of the individual house? , If the diagnosis of the phenomena denotes perceived repetition of the cases , So what's size of this transposes on the architectural design of t

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Publication Date
Sun Jan 01 2023
Journal Name
Dental Hypotheses
Assessment of Salivary Levels of the RANKL and RANK in Patients with Healthy Gingiva on Reduced Periodontium Versus Periodontitis: An Analytical Cross-Sectional Study
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Publication Date
Fri Sep 09 2022
Journal Name
Journal Of Ovonic Research
Confinement factor and carrier recombination of InGaAsP/InP quantum well lasers
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Low-dimensional materials have attracted significant attention in developing and enhancing the performance of quantum well lasers due to their extraordinary unique properties. The optical confinement factor is one of the most effective parameters for evaluating the optimal performance of a semiconductor laser diode when used to measure the optical gain and current threshold. The optical confinement factor and the radiative recombination of single quantum wells (SQW) and multi-quantum wells (MQW) for InGaAsP/InP have been theoretically studied using both radiative and Auger coefficients. Quantum well width, barrier width, and number of quantum wells were all looked at to see how these things changed the optical confinement factor and

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Publication Date
Sat Oct 01 2022
Journal Name
Nuclear Instruments And Methods In Physics Research Section B: Beam Interactions With Materials And Atoms
Shielding properties and buildup factor of Al2O3/PbO-based ceramic materials
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Publication Date
Thu Oct 01 2020
Journal Name
Journal Of Engineering Science And Technology
Water quality assessment and sodium adsorption ratio prediction of Tigris River using artificial neural network
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