Pregabalin
female rat
sex hormones
Offspring Weight and Number
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Abstract: This study was aimed to investigate the effect of two doses of pregabalin (PGB) on hormonal level and sexual activity in
female albino rats. Ninety female rats with age (9-10 weeks) and weight (200±20 g) were divided into three major groups of thirty rats.
First group was considered as control G1, the second G2 and third G3 groups were exposed to PGB into two doses 150, and 300 mg/kg
body weight per day respectively. Each major group was divided into three subgroups (subgroup A, B, and C of each has ten rats), the
treatments last for one month for subgroup A, two months for subgroup B, and three months for subgroup C. Five rats from each
subgroup were placed separately into two breeding cages with two isolated males and wait
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