Researcher Image
ازهار مهدي جاسم مهدي - Azhar Mahdi Jasim
MSc - lecturer
College of pharmacy , Department of pharmaceutical chemistry
[email protected]
Summary

I graduated with a degree in Science of Pharmacy in 1991 from the College of Pharmacy / University of Baghdad and then went to Al-Alawiya Teaching Hospital for childbirth as a Pharmacist Trainee for one year, then I went back to the College of Pharmacy / University of Baghdad as a demonstrator in Pharmacognosy department. In 1997 I graduate with a degree of Master of Science of Pharmacy / Pharmaceutical Chemistry. Then after as an Assistant lecturer in the Department, then promotion was continued to Lecturer. I have supervised numerous of graduation projects.

Qualifications

 B.Sc. Pharmacy (1991), College of Pharmacy, University of Baghdad  M.Sc. Pharmaceutical Chemistry (1997), College of Pharmacy, University of Baghdad

Responsibility

Teaching

Awards and Memberships

Member of Iraqi Pharmacist Syndicate Member of Department of Pharmaceutical Chemistry Member of the Psychological Counseling and Educational Guidance Unit

Research Interests

I am interested in research dealing with synthesis of new organic compounds that have a biological activity as anti-bacterial and antifungal effect.

Academic Area

Pharmaceutical Chemistry

Teaching

 Organic Pharmaceutical Chemistry I  Organic Chemistry II  Practical Organic Chemistry II  Practical Organic Chemistry III  Pharmaceutical Chemistry II  Pharmaceutical Chemistry I Organic Pharmaceutical Chemistry III Practical Pharmaceutical Organic Chemistry I Practical Pharmaceutical inorganic Chemistry Practical Pharmaceutical Organic Chemistry III

Publication Date
Thu Oct 03 2024
Journal Name
Pharmacia
Synthesis and preliminary antimicrobial evaluation of new 7-amino-4-methyl-coumarin thiazolidinone conjugates

Abstract As a part of our ongoing project on the design and synthesis of new 4-thiazolidinone derivatives with antimicrobial activity, four new 4-thiazolidinone derivatives carrying bromo, nitro, methyl, and chloro groups on the benzene ring were synthesized by starting with the 7-amino-4-methylcoumarin moiety, linking coumarin with various phenyl isothiocynate to form the thiourea group, and then cyclizing the derivatives, characterized by IR and 1HNMR, and assayed in vitro for their antimicrobial activity against Gram positive and Gram negative bacteria and fungi. Overall, 2-(4-methyl-2-oxo-2H-chromen-3-yl)-3-(4-nitrophenyl) thiazolidin-4-one to be the most powerful individuals in the series. Based on the observed data, it can be sta

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Publication Date
Thu Apr 27 2023
Journal Name
Al-rafidain Journal Of Medical Sciences ( Issn: 2789-3219 )
Anticancer Activities of Some Heterocyclic Compounds Containing an Oxygen Atom: A Review

The purpose of this study is to underline the progression and development of research regarding oxygen-containing heterocycles as well as the contribution that some oxygen-containing heterocycles have made as anticancer medicines. A series of publications about the antitumor effects of derivatives of heterocyclic compounds containing an oxygen atom, such as furan, benzofuran, oxazole, benzoxazole, and oxadiazole, were evaluated, and their anticancer activities showed encouraging results when compared to those of established standard treatments.

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Publication Date
Tue Feb 01 2022
Journal Name
Macromolecular Symposia
Synthesis of 5‐Fluorouracil–Naproxen Conjugates as a Mutual Prodrug for Targeting Cancer Tissues
Abstract<p>A new 5‐fluorouracil–naproxen conjugate is synthesized as a mutual prodrug for targeting cancer tissues. The structure of the target compound and their intermediate are characterized by their melting point, IR, <sup>1</sup>H NMR, <sup>13</sup>C NMR, and elemental microanalysis. The cytotoxic activity is preliminarily evaluated using nonsmall lung cancer CRL‐2049, human breast cancer CAL‐51, and one type of normal cell line; rat embryo fibroblast cell line. The synthesized compound shows a good cytotoxic effect at the cancer cell and no significant effect at rat embryo fibroblast cell line.</p>
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