Background: The problem of excessive alcohol consumption is a major cause of public health concern in most countries of the world today. Royal Colleges of Physicians and Psychiatrists recommended that every inpatient should be screened with a questionnaire for alcohol related problems. Therefore, this work was carried out to report on alcoholism in the emergency unit in two general hospitals in Baghdad, Iraq.
Methods: The study was carried out in Al-Sader general hospital (Al-Sader city, Baghdad) and Baghdad teaching hospital (Baghdad) for the period 1st July 2008 to 1st May 2009. Data collection was two days per week. Version of 25 items Michigan Alcoholism Screening Test (MAST) and semi-structured 

Background: Although studies regarding the role of religious beliefs in psychological well being are relatively recent, the importance of people’s religiousness and spirituality for their health status has been widely acclaimed based on hundreds of published studies.
Patients and Methods: The Arabic Modified version of WHOQOL-SRPB (World health organization quality of life-spirituality, religiosity and personal belief) questionnaire was self
administered to a systematic random sample of 100 fifth year medical students.
Results: Around a quarter (21-28%) of subjects perceived religiousness as very to extremely important. This percentage raised to 38% for spirituality and further to 61% for personal believes.

Background: Primary myelofibrosis is a chronic myeloproliferative neoplasm characterized by abnormal megakaryocyte proliferation and fibrosis that destroys healthy bone marrow. This results in extramedullary hematopoiesis, variable blood cell deficiencies, hepatosplenomegaly, general symptoms, progression to leukemia, and a reduced lifespan. Myelofibrosis can occur as a de novo myeloproliferative neoplastic disorder or evolve from other myeloproliferative neoplasms, including Polycythemia Vera or Essential Thrombocytosis. MicroRNAs (miRNAs) are short, non-protein-coding RNA molecules, typically 18–24 nucleotides in length. Dysregulation of miRNAs may contribute to the disease phenotype.

Background:

Background:

Background: Squamous carcinoma accounts for majority of esophaged cancinoma Most patients with esophaged cancer are middle aged or elderly with make to female ratio 2.5:1.
Aim of study : to present a fairly representative picture of the carcinoma of esophagus in' yemen.
Patients& Methods: Seventy-six patients were treated for carcinoma of esophagus over a 5 - year period by cardiothoracic and vascular surgeon working in Sana a - Yemen. Amongst them there were thirty one men and forty-five women, with male/female ratio 1:1.45, age incidence (range 38 - 40year).
Results:. Adenocarcinoma was 65% of cases and other 35% was squamous cel! carcinoma. The major risk factors were founded chewing quat, silicon particles, thermal injur

خلفية البحث: فحص الأمواج فوق الصوتية للجيب الوجني يوفر معلومات هامة للطبيب السريري عن تشريح الجيب الوجني وأمراضه من خلال فحص سريع وغير اجتياحي.

هدف البحث: تقييم فعالية فحص الامواج فوق الصوتية لأمراض الجيب الوجني  بالمقارنة مع مشاهدات المفراس الحلزوني.

الطرق والمرضى: دراسة وصفية مقارنة بين فحص الأمواج فوق الصوتية للجيب الوجني

الخلفية:

يعتبر اوكسيد النتريك من العناصر الفسلجية والمهمة في تنظيم حركية السائل المائي للعين. من جهة أخرى فان المركبات التي تعتمد في فعاليتها على اوكسيد النتريك قد تعمل على زيادة تصريف السائل المائي للعين وبالتالي في انخفاض الضغط الداخلي للعين 

الأهداف: 

السلدينافيل من الأدوية المثبطة للإنزيم الفوسفودايستريز -5 والتي تعمل على زيادة تحري

خلفية: بروتينات الصدمة الحرارية يكون لها دور عام في الاستجابة للجدران الشرايين إلى التوتر ويمكن أن تكون بمثابة وسيط / محفز لتصلب الشرايين في ظروف معينة عندما HSPs ربط خصيصا لمجمع تول مثل مستقبلات 4/CD14، الشروع في المناعة الفطرية ردا على ذلك، بما في ذلك إنتاج السيتوكينات الموالية للالتهابات، وهذا يتبعه أيضا من خلال التضخيم خلوى التهجير من الضامة والعدلات.

الهدف: تحقيق في النسبة الم

Background and objectives: P53 gene mutation and deletion are among the important molecular markers linked to lung cancer. In most cases, the inactivating mutations affecting both p53 alleles are acquired in somatic cells. Less commonly, the mutations are inherited ones. The aim of the present study was to analyze the frequency of having a wild and/or a mutated p53 gene in lung cancer compared to benign lung lesions and to relate these findings to different morphological types and grades of lung cancer.
Patients, materials and methods: In this retrospective study, the histopathology blocks of 30 lung cancer cases covering the period from2002 to 2007were obtained from the archives of the histopathology sec

Background: It is well known that the low level laser irradiation has act on immune system cells in a number of ways, one of them includes increasing phagocytic activity of irradiated cells. This study was established to shed light on the possible effect of laser irradiation on phagocytic activity of polymorphoneutrophils.
Subjects and methods: Fresh blood samples were obtained from twenty healthy volunteers for phagocytosis assay. The polymorphoneutrophils were isolated from blood and examined their phagocytic capacity befor and after exposure to laser irradiation.
Results: The present study revealed a significant increase in the mean percentage of phagocytosis after exposure to diode laser of wave le

Background: Cherry extract has a wide range of biological activity. In the present investigation, two oral doses 0.04&0.08 mg/kg/day of cherry stick (ethanol extract) in albino male mice resulted in a significant decrease in concentration of serum total cholesterol concentration, triglyceride and total protein, albumin and globulin.
Objective: we investigated the impact of biological activities of cherry stick extract on serum cholesterol, triglyceride, total protein, albumin and globulin in white albino male mice.
Design: This study include three groups of white albino male mice. The first group (G1) was a control group comprised of 5 animals. The second group (G2) consisted of 5 animals treated with 1

Background: Rheumatoid arthritis (RA) is a chronic and debilitating autoimmune disease characterized by chronic inflammation with subsequent cartilage and bone destruction. Cytokines are  key mediators of inflammation and can be found in abundance both in the joint and blood of patients. This study was designed to evaluate the role of pro- and anti-inflammatory cytokines in pathogenesis of RA, as well as study the correlation among these cytokines.
Patients and methods: Forty patients with RA and thirty age-matched healthy controls were included in this study. Serum cytokines were measured by enzyme-linked immunosorbent assay.
Results: The serum levels of pro-inflammatory cytokines (IL-1α, IL-2, IL-6, IL-8

Back ground: Anaemia is one of commonest health problems in antenatal care units of developing countries and contributes significantly to increased maternal and fetal morbidity and mortality.
Patients and methods: During the period from 1st of July 2007 to the end of October 2007, hundred anaemic pregnant women attending the gynaecology and obstetrics department in Al- Yarmook teaching hospital in Baghdad and 20 apparently healthy pregnant women,aged between 17 - 46 years as a control were included in this study. Anaemic women included in this study fulfilled the criteria of haemoglobin concentration of less than 110 g/L in first trimester and 105g/L in the second and third trimesters, no history of acute

Background: Patient evaluation of the healthcare provided by his/her family doctor is a multidimensional concept, its main component being the doctor-patient interaction.
Materials and Methods: a total of 200 client chosen by systematic random sampling were successfully interviewed immediately after having the contact with the family physician in the family medicine center.
Results: The present study showed that the majority of the clients were young age, most of them were female, completed secondary education and the majorities were unemployed. This study determined the client general satisfaction the services provided by the physician the overall satisfaction was high (98%), the most significant stat

Background: IL-4 is an antibodies inflammatory cytokine which has an important role in protecting against the inflammatory reactions in most of diseases. Here, we try to highlights the role of this cytokine in chronic Rheumatic heart disease and its correlation with the extent of histopathological abnormalities.
Patients and Methods: Rheumatic mitral valve surgical fragments were taken from a total of 48 Iraqi patients with chronic rheumatic heart disease under mitral valve replacement surgery in Ibn Al- Bitar Hospital for Cardiac Surgery-Iraq-Baghdad. Paraffin embedded mitral valve tissue sections were prepared. IL-4-expressing cells were detected by using immunohistochemical staining technique and

Background: In Ulcerative colitis (UC), the presence of a persistently elevated number of T cells in the inflamed area with respect to the activity of the disease suggesting bad prognosis. This study was done to evaluate cellular immune response in different disease activity patterns and its possible implication in evaluation of disease activity.
Materials and methods: This study included Forty seven archived paraffin-embedded samples of ulcerative colitis; these samples diagnosed and graded for disease activity. Then dual
immunofluorescence staining was used for phenotyping of lymphocytic infiltrate (CD3- CD19) and (CD4-CD8). A total and differential T cell as well as plasma cell count was recorded in thes

Rupture of the trachea or main bronchus can occurs during severe chest trauma and this event has been reported since more than a century. This is a report of a 19 year old male patient sustained car accident leading to loss of consciousness due to multiple trauma ,involving specially the head and the chest that he needs assisted ventilation in an intensive care unit and later a tracheostomy .The patient regain his consciousness gradually , and a late diagnosis of traumatic rupture of the left main bronchus , which was approved by bonchoscopy and CT chest .Surgical repair of the ruptured left main bronchus was accomplished sixty days from the admission with the lung fully expanded on a post operative che

خلفية: التسرطن القولون والمستقيم الإنسان هي عملية معقدة، عملية متعددة الخطوات وmultigenetic. مصفوفة الفلزي-2 و 2-انزيمات الأكسدة الحلقية هي انزيم رئيسي في تدهور المواد خارج الخلية، وأعرب أكثر من ظهائر في عدة مثل غدية القولون والمستقيم.

الأهداف: تم تصميم هذه الدراسة للكشف عن التعبير عن مصفوفة الفلزي-2 و 2-انزيمات الأكسدة الحلقية في المرضى الذين يعانون من سرطان القولون والمستقيم والعلاق

الخلفية :- دراسة نخاع العظم لازالت هي النقطه الاساسيه التي تعكس فعالية ونشاط نظام بناء الخلايا الدمويه, الامراض الدمويه وبعض الامراض العامه في جسم الانسان.

ان من الصعب اعطاء التشخيص النهائي لامراض الخلل النخاعي المتشعب لحد الان بسبب تشابه المؤشرات والخواص الطبيه بالاضافه الى النسيجيه مثل تليف نخاع العظم والذي يعتبر مهما لانه يؤثر بشكل من الاشكال على نشاط نخاع العظم.

Background:The diabetogenic agent alloxan is a selective necrosis of insulin producing cells .Alloxan accumulated rapidly in liver and pancreatic islets , this study was carried out to evaluate the antidiabetic effect of cinnamon oil on the destructive effect of alloxan in liver and intestine diabetic tissues .
Materials and methods:Thirty male rats were used and divided into threegroups: Group I =10 animal controls, Group II =10 treated with alloxan, Group III = 10 treated with alloxan + cinnamon oil . 
Results:Liver and intestine tissues of diabetic groups revealed necrotic, degeneration of cells (histologically ) , increase in blood serum enzymes for acid and alkaline phosphatase , total protein&nbs

Background: Acrylic resin dentures are susceptible to fracture; it is unresolved problem in prosthodontics. The repair procedure should be simple, strong, and accurate. This study evaluated the transverse and impact strength of autopolymerizing acrylic resin, the repair material was modified with kraft lignin as a new enforcement material and compared with the commercially available self cured acrylic resin.
Materials and Methods: The addition of kraft lignin to the acrylic resin were done in percentages of 0.25%, 0.5%, 0.75%, 1.0%, 1.25%, and 1.5% (wt%). Seventy specimens were made according to the ADA specification No 12 for transverse strength using three point bending test and Impact strength tes

Background: Hydatidosis is a widespread chronic zoonotic disease caused by helminthic larval stage of tapeworm Echinococcus granulosus. It has a serious medical and public health problem. Recently many substances are used to activate and modulate the immune system of the host in order to control the cyst growth and development.
Materials and Methods: Protoscolices were isolated from human hydatid cysts and treated with four purified concentrations (25, 50, 75, 100μm/ml) of 1-HP plus hydatid cyst fluid as a positive control group for 4, 24, 48 and 72 hrs period of exposure. Then After 72 hours, the protoscolices which were treated with different concentration of 1-HP were inoculated intraperitonially of m

Background:The most principal mechanisms of cardiomyopathies are;high preload and afterload and low myocardial contractility, imbalance of trace elements may cause myocardial metabolic dysfunction and may have a role in aetiology of cardiomyopathy, particulary in IDC. Trace elements are being increasingly recognized as essential mediators of the development and progression of heart diseases.
Methods: Study design Multi case-control study and single center estimation of trace elements concentrations in a number of volunteer settings this study was conducted in the Department of Cardiology, Ibn Albitar Hospital, and in the Physiological Chemistry Department of the College of Medicine, Baghdad University, fr

Background:Aluminum (Al) intoxication was initially reported in patients undergoing hemodialysis and then was linked to Alzheimer's disease. Man usually is exposed to Al containing antacids, vaccines or foods cooked in Al utensils. The assumption of ingesting sour juices as acetic acid or ethanol may affect favorably the degree of Al absorption is justified when taken in conjunction with the above mentioned appetizers.
Materials and methods: Four groups of 10 mature male rats each were used. The drinking water (DW) containing 5mM of Al2(SO4)3 with 1% glacial acetic acid and/or 10% ethanol made available ad-libidum. Weekly body weight and each other day drinking water volume were measured. Brain and p

Background: Hormones have very important role in spermatogenesis and production capacity of testis. Disturbances in their vlevels can be very crucial in dysfunction of testis which results in men infertility. This study carried out to evaluate the hormonal disturbances in men infertility and its correlation with semen parameters and types of infertility.
Patients and Methods: Blood and semen samples were collected from 91 infertile men and 20 healthy and fertile control who attended Al-Kadymiah hospital and some private clinics in Baghdad from January to December 2009.Semen and serum samples were analysed for semen parameter and FSH, LH, Testosterone and prolactin levels.
Results: Fifty one (56%) of in

Background: Sildenafil is a drug that is used to treat erectile dysfunctions, it acts by inhibiting CGMP specific phosphodiesterase type 5, an enzyme that regulates blood flow in the penis. The most common adverse effects of sildenafil are headache, dyspepsia, nasal congestion and impaired vision which includes photophobia and blurred vision. Many dermatological side effects are present like flushing, urticaria, sweating and many others.
Patients and Methods: Fifty six males were included in this study, with ages between 37 – 60 years and a mean age of 50.1 ± 7.1years. The study was conducted from November 2004 till May 2009 in the Department of Dermatology of Al-Kadhymia Teaching Hospital in Baghdad;

Background: Neonatal jaundice (NJ) is a common problem worldwide and frequent in Iraq . Several reports were published on prevalence, distribution, causes and treatment of NJ.This clinical trial was carried out to demonstrate the effect of combinations of Castrol oil, riboflavin and magnesium in mechanical elimination of bilirubin after enhancing hepatic excretion by phototherapy.
Patients & methods: This clinical trial included a total of 61 significantly jaundiced neonates who were admitted to the special care baby unit of Children Welfare Teaching Hospital, medical city complex, Baghdad, Iraq, during the period June 1st to Dec.31st 2007. Phototherapy was applied alone in 30 neonates (group 1) and p

Background: Fenugreek seeds are used as food ingredient in traditional medicines; also aspirin is an incredible chemical with many useful benefits in the medical field. The objective was to study the effect of aspirin and fenugreek on testes of mice.
Method: 20 white male mice weighing (18-23gm) were divided into four groups 5 each. Group 1, represented control, group 2, mice treated with fenugreek seed (100mg/KgB.W), group 3 mice treated with aspirin (10mg/Kg B.W), group 4 mice treated with aspirin and fenugreek seed for 21 days. Body weight and testes weights were recorded. Histopathological examination of testes was carried out.
Results: a significant decrease (P<0.05) in body weight of mice treated w

الخلفيه العلميه: تصلب الشرايين القلبي واحدة من الأمراض الألتهابية  ينتج عن  التركيز العالي للكولسترول فى المصل بالأخص عند الأشخاص  الذين لديهم الدهون البروتينية الواطئة الكثافة ((LDL للكولسترول  بتراكيز عالية والتي تعد أحد العوامل الخطرة لهذا المرض .

الهدف من الدراسه:الدراسة الحالية ركزت على تشخيص اكثر العوامل الخطرة ومؤشرات امراض القلب لغرض تطوير