الخلفيه النظريه: الكروموجرانين أ هو احد دلائل الاورام المفيده جدا لتشخيص اورام الصم الغدية العصبية ومتابعتها وان عقار الاوكتيريوتايد اثبت فعاليته في علاج هذه الاورام وان الدراسات المتعلقه بالعلاقه بين الاستجابه لعقار الاوكتيريوتايد و مستوى الكروموجرانين في الدم لا تزال غير كافيه
الغرض من الدراسه: دراسه التغير لمستوى الكروموجرانين في الدم وعلاقته ب
... Show Moreالمقدمة: تعتبردراسة كهروفسلجة القلب من الفحوصات القسطارية الضرورية لدى المرضى المصابيين بالتسارع الأذيني الأنتيابي والذي يحدث بسسب ظاهرة عودة الدخول الكهربائي حول العقده الاذينية البطينية.
الاهداف : تهدف هذه الدراسة الى معرفة الاهمية السريرية لكهروفسلجة القلب في تقييم مرضى التسارع الاذيني الانتيابي حول العقده الاذينيه . لقد خضع المرضى الى
... Show Moreالخلاصة: يعد سرطان الثدي من اكثر الاورام الخبيثة التي تصيب النساء في العالم والعراق. ان معدلات التكاثر السرطانية تستطيع ان توفر معلومات مفيدة عن عدائية المرض و ما يؤل اليه في المستقبل كما و يمكن استخدامها في الممارسة الاكلينيكية لتحديد برتكول العلاج.
اهداف البحث: تقييم دور Ki67 كمعلم تكاثري من خلال تحليل العلاقات بين Ki67 مع العوامل السريرية والباثولوج
... Show Moreخلفية عن الدراسة: المعلم المناعيWT1 هوعامل نسخ ويقع في الكروموسوم 11p13, اكتشف لأول مرة في الورم الكلوي ((Wilms حيث انه يعمل كمثبط للجينات السرطانية , كما يوجد في عدة أورام من ضمنها أورام المبيض وأورام الدم الخبيثة, وفي الآونة الأخيرة وجد بان WT1 له أيضا دور في تكوين الأوعية الدموية.
هدف الدراسة: صممت هذه الدراسة للبحث عن العلاقة بين المعلمات المن
... Show Moreخلفية: احتشاء عضلة القلب (MI) هو الأكثر شيوعا نظرا لانسداد (انسداد) في الشريان التاجي بعد تمزق لوحة تصلب الشرايين عرضة للخطر. وقد اقترح أن الأنسجة الدهنية قد تلعب دورا مهما في التوسط في هذه العملية التهابي مزمن. وتشارك الاستجابات الالتهابية في بدء وتطور لويحات تصلب الشرايين. رزيستين هو ببتيد السيستين الغنية التي أعرب عنها في مستويات منخفضة نسبيا في adipocytes الإنسان، ولكن مستويات أعلى في الضامة. الأنس
... Show Moreخلفية: هناك أدلة كثيرة على القلب والأوعية الدموية التي تربط الاعتلال والوفيات مع السمنة، ولكن، لها تأثير مباشر للسمنة غير معقدة في وظيفة القلب ليست راسخة.
الهدف: لتقييم العلاقة بين مؤشر كتلة الجسم (BMI) واليسار هيكل البطين وظيفة.
الطرق: أجريت هذه الدراسة مستعرضة خارجا على (146) البالغين الأصحاء على ما يبدو من كلا الجنسين (85 من الذكور والإناث 61) تتراوح أعمارهم بين 20-59
... Show MoreBackground: Congenital adrenal hyperplasia is a family of autosomal recessive disorders of cortisol biosynthesis. Depending on the enzymatic step that is deficient, there may be signs, symptoms, and laboratory findings of mineralocorticoid deficiency or excess; incomplete virilization or premature puberty in affected males; and virilization or sexual infantilism in affected females. The most frequent is 21-hydroxylase enzyme deficiency, accounting for more than 90% of cases.
Objectives: to review cases of congenital adrenal hyperplasia registered in children welfare teaching hospital- medical city- Baghdad.
Patients and method: This study included all patients who were presented and registered in the e
Background: Although the issue of anemia after renal transplantation (RT) has received increasing attention lately, the data on the exact prevalence of post-transplantation anemia (PTA) in the Iraqi patients are limited.
Objective: In this study we sought to determine the prevalence of PTA among Iraqi patients and to correlate the renal allograft function measurements and the use of immunosuppressant with the prevalence of anemia.
Patients and Methods: One hundred and twelve (74 male, 38 female) kidney transplant recipients (KTR) attending the kidney transplant center at surgical specialties hospital were studied. All patients were on maintenance, combined immunosuppressive therapy. The renal function
Background: one of the complications of rigid bronchoscope is the cardiovascular responses that may carry a dangerous drawback during and after the procedure. Prevention and control of these events will be crucial, especially for the old and cardiovascular debilitated patients.
Objective: The study aims to control and attenuate the unwanted hemodynamic responses to the rigid bronchoscpe using intravenous lidocaim and GTN.
Method: a study was performed on three groups of patients undergone a diagnostic procedure of bronchoscope. Each group consists of 20 patients at the same age and relatively similar pathology. The three groups (group one, two and three) received lidocaine, glyceryltrinitrate and no drug re
المقدمة: الإصابة بفيروس التهاب الكبد الوبائي (سي) هو أحد الأسباب الرئيسية لأمراض الكبد المزمنة، قدرت منظمة الصحة العالمية أن حوالي 170 مليون شخص مصابون بالتهاب الكبد الوبائي (سي)، ثبت مؤخرا أن سيليمارين (ليكالون) فعال في علاج التهاب الكبد الوبائي (سي).
الاهداف: فعالية سيليمارين (ليكالون) على الحمل الفيروسي في المرضى الذين يعانون من التهاب الكبد الوبائي (سي).
... Show Moreالهدف: هو تسجيل حالة دبوس اخترق الفم، اختراق قاعدة الجمجمة والمنطقة العنقية العليا، والتي نادرا ما تذكر في البحوث الطبيه، ومقارنتها مع الدراسات الأخرى التي تقدم تقارير مماثلة.
ويسرد الباحث تفاصيل الحاله السريريه و الشعاعية, و نهج العمليات الجراحية في مثل هذه الحاله.
تم التأكد من التشخيص بالأشعة السينية والتصوير المقطعي العادي مع دراسة العظم. و تم اجر
... Show Moreالخلفية:
ان مرض ابيضاض الدم الليمفاوي المزمن CLL)) هو سرطان من الدرجة المنخفضة للخلايا اللمفاوية نوع بي. وفى عدد من الدراسات وجد إن كلا من 67 k وهو بروتين كبير موجود في نواة الخلية وهومرتبط مع تكاثر الخلايا و الجين الورمي – Bcl2المقترن باختلال توازن المسار الجوهري للموت المبرمج للخلايا , يرتبطان بسوء التكهن ومقاومة الاستجابة للعلاج الكيميائ
... Show Moreالخلفية : داء السكري النوع الأول هو نوع من داء السكري الناتج من تحطم مناعي ذاتي لنوع من خلايا البنكرياس الفارزة للأنسولين التي تؤدي إلى النقص ألدائمي للأنسولين, يصنف النوع الأول من داء السكر إما إيجابي أو سلبي بالنسبة إلى الأجسام المضادةالذاتيه المختلفة ذات صلة بوظيفة البنكرياس .ومن الأجسام المضادة حمض أنتي كلوتامك دي كربوكسيليز يميز باعتباره واحدا من العلامات المصلية الرئيسية لداء
... Show MoreBackground: the different roles of cytokines IL-4, IL-10, IL-12p40, IFN- during acute toxoplasmosis disease in pregnant women.
أنتفاخ الفص الرئوي الخلقي هي من الحالات النادرة ولكن الخطيرة والتي تتطلب تشخيص وعلاج مبكر وهي عادة ما تظهر نفسها بوقت مبكر بعد الولادة.
منهجية وطرائق البحث: هذه دراسة بأثر رجعي تهدف الى أعادة النظر والتقييم لمنهجية العلاج لحالات الأنتفاخ الفص الرئوي الخلقي التي تمت في قسم جراحة الصدر والأوعية الدموية في مدينة الطب التعليمية وتهدف أيضاً الى تثبيت وتوثيق المشاهدات
... Show Moreالخلفيه:
ان هذا البحث يعمد الى دراسة فعالية الفحص بالأمواج فوق الصوتيه المهبلي بعد حقن كمية من المحلول الملحي المتعادل في تقييم امراض بطانة الرحم لحالات النزف بعد سن اليأس .
المرضى والطرق: خلال الفترة مابين تشرين الثاني 2011 ولغاية شهر أيار 2012 في مستشفى بغداد التعليمي التابع لمدينة ا لطب .تم تحري 40 مريضة تعاني من النزف الرحمي بعد سن اليأس بأستخد
... Show MoreBackground: Pre-eclampsia is culmination of a multi-step process that related in part to elevated oxidative stress and associated with hyperurecimia.
Patients and methods: Thirty normotensive and hundred pre-eclamptic pregnant women attending to Al-Basra hospital of pediatrics, obstetrics and gynecology were participated in this study. The patients were randomized into six groups. They were treated with methyldopa alone, methyldopa plus vitamin C, methyldopa plus vitamin E, methyldopa plus vitamin C and E, and methyldopa plus allopurinol. The oxidative stress (MDA), renal function parameters, systolic and diastolic blood pressure were evaluated before treatment and 14 day after initiation of therapy.
R
Background: Polycystic ovary syndrome is the most common cause of anovulation, and the number of antral follicles is of great importance in determining ovarian reserve, so identification of patients with diminished ovarian reserve help in choosing individualized and well managed ovulation induction protocol. The aim of the study is to find out if the number of ovarian antral follicles could affect the amount of gonadotropins used in ovarian stimulation in polycystic ovarian patients.
Patients and methods: Ninty four infertile polycystic ovaries women, attending the infertility clinic at Baghdad teaching hospital, during the period of November 2005 to October 2006, were compared to 62 control group women w
Background: “The absolute refractory” period is the time interval during which the nerve fiber is in capable of conducting another impulse after a conditioning stimulus and the determination of the refractory period distribution in a nerve can give a good idea about the characteristics of the conducting fibers constituting that nerve as it reflects their excitability and could be used as a sensitive indicator for the ability of the nerve fiber to conduct pairs of closely spaced impulses.
Methods: The new collision test was used to measure precisely the absolute motor refractory period and the paired shock technique to measure the absolute sensory refractory period in the ulnar nerves of 167 normal in
Background: Inflammation contributes across the spectrum of cardiovascular disease, including the earliest steps in atherogenesis. Myocardial Infarction (MI) is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque. It has been suggested that the adipose tissue may play an important role in mediating this chronic inflammatory process, human resistin, is a 12.5-kDa protein, it found in the inflammatory zone. Interleukin-6 (IL-6) is a pro-inflammatory cytokine, it secreted by T cells and macrophages to stimulate immune response. C-reactive protein (CRP) is a protein found in the blood, the levels of CRP rise in response to inflammation.
... Show MoreBackground: Delayed interval cholecystectomy can be performed to overcome the logistical difficulties in performing ‘early urgent’ laparoscopic cholecystectomy (LC) within 72 hours of
admission with acute cholecystitis (AC), and to avoid earlier re-admission with recurrent AC in patients waiting ‘delayed interval’ cholecystectomy.
Objectives: To evaluate the safety and feasibility of ‘delayed urgent’ LC performed beyond 72 hours.
Methods: Patients admitted with AC were scheduled for urgent LC. Patients who underwent ‘early urgent’ LC were compared with those who had ‘delayed urgent’ surgery.
Results: Fifty consecutive patients underwent urgent LC for AC within 2 weeks of admission. Ther
Background: Helicobacter pylori represents the major etiologic agent of gastritis, gastric and duodenal ulcer disease and can cause gastric cancer. Diagnostic testing for Helicobacter pylori can be divided into invasive and non-invasive techniques based upon the need for endoscopy. Serological test is one of the non – invasive tests although measuring these antibodies is not reliable method of diagnosis but may be used in certain condition.
Objectives: To evaluate serum IgG antibodies against Helicobacter pylori by ELISA technique.
Patients and Methods: The current study consisted of 115 patients (74 males, 41 females) attending The Gastrointestinal tract Center and Gastroscopy department in Baghdad Medical City and was subjected
Background:Varicoceles, present in 15% to 20% of men, are the most common abnormal finding among men presenting with infertility, yet controversy exists regarding their etiology. Anecdotal experience suggests that varicoceles are more prevalent in lean men, supporting the "nutcracker" effect of the superior mesenteric artery compressing the left renal vein over the aorta.
Materials and methods: A total of 206 males with varicocele attending the urological out patient clinic were evaluated from their physical screening examinations. All subjects underwent history taking and physical examinations to evaluate for the presence and severity of varicocele ht,weight and BMI, those compared with 206 men without v
Background: Indeterminate colitis (IC) originally referred to those 10–15% of cases of inflammatory bowel disease (IBD) in which there was difficulty distinguishing between ulcerative colitis (UC) and Crohn’s disease (CD) in the colectomy specimen and histopathology examination. However, IC is increasingly used when a definitive diagnosis of UC or CD cannot be made at colonoscopy examination, colonic biopsies or at colectomy. The diagnostic difficulties may explain the variably reported prevalence of IC. Clinically, most patients with IC evolve to a definite diagnosis of UC or CD on follow up.
Patients and methods: PATIENTS GROUP: Consisted of 80 patients with indeterminate colitis (IC), their ag
Background: β-thalassemia major is a genetic disorder characterized by reduced rate of β-globin chain production. Clinically, β-thalassemia major is a severe, transfusion-dependant disorder; repeated blood transfusion will lead eventually to chronic liver disease.
Patients and Methods: One hundred patients ; 56 males and 44 females who were known cases with β-thalassemia major on regular blood transfusion, aged between 6 months and 18 years, were studied in a private pathology laboratory, between January 2002-January 2006.Blood was drawn to estimate serum glutamic pyruvate transaminase (SGPT) and serum glutamic oxaloacetic transaminase (SGOT) levels.
Results: Sixty-six patients (66%) had elevated S
Background: In Iraq, Primary Health Care (PHC) services are provided trough a network of about 1900 PHC Centers (PHCC). Recently, attempts were made to enhance the practice of primary health care to encompass the family health model. Expressed attendants' satisfaction and opinion about provided care at any health care setting is an important predictor of utilization and continuity of obtaining care from the same source. The objective: is to describe and compare satisfaction of attendants of a Family Medicine Training Center (FMTC) and a PHCC in Baghdad.
Subjects and Methods: a comparative cross sectional study conducted on a random sample of 300 attendants from each center. Attendants’ satisfaction towa
Background: Fibromyalgia syndrome (FMS) is a common rheumatologic syndrome with multiple systemic manifestations & associated with many diseases. The aim of the study is to assess the relationship between FMS and BMI (Body mass index) in a sample of Iraqi patients.
Patients and Methods: Fifty patients with FMS, 46 (92%) females and 4 (8%) males; their mean age (47.44), and 25 healthy control individuals were studied; 13 (52%) are females and 12 (48%) are males, their mean ages (41.4) years. All FMS features and criteria are studied for patients and control, patients with secondary FMS was excluded. Body mass index (BMI) is determined for both groups.
Results: The ratio between female and male was
Background: Patients who undergo craniectomy or removal of part of the skull bone following trauma to give a release to the brain are later managed by auto graft, or synthetic acrylic graft.
Patients and method: 20 patients transferred to specialized surgical hospital from U.S mellitary Ibn Sinna hospital with removal the skull bone implanted in the abdomenol wall or thigh and managed by returning of the bone to the scalp compared with 20 patients managed in our hospital to start by craniectomy and implantation of a synthetic bone graft acrylic, the comparism included the surgery, time of delay, out come, complication.
Results: We divided the patients to group A and B, A were the ones treated by Autograft &
Background: Life-long red blood cells (RBCs) transfusion remains the main treatment for severe cases of thalassaemia. The development of anti-RBC antibodies (alloantibodies and for
autoantibodies) can significantly complicate transfusion therapy. Some alloantibodies are hemolytic and may cause, though not invariably, hemolytic transfusion reactions and limit the availability of further safe transfusion. Erythrocyte autoantibodies appear less frequently in blood cross match.
Patients and methods: This is a descriptive study ducted at Al-Karama Thalassaemia Center in Baghdad .The sampling was done from September 2005 to April 2006 and all patients were diagnosed as Thalassaemia Major according to the hemoglob
Background: Human leukocyte antigen (HLA) is the most polymorphic genetic system in man. The genes of this region seem to influence susceptibility to certain diseases.
Patients and methods: Polymerase chain reaction-Sequence Specific Primers PCR-SSP is the method used to asses HLA-typing of 100 blood samples of 60 AIH patients and 40 healthy normal controls.
Results: An increased frequency of HLA-DR3, DR4 and DR7 was observed for patients group versus control group with P-value (0.0001, 0.05, and 0.001) respectively, while DR*0211 (DR2) may be formed the basis for protection against the disease. HLA-DQ on the other hand, yielded on association in Iraqi patients with AIH.
Conclusions: This finding de