Background: Aspergillus spp. causes a wide range of diseases called Invasive Aspergillosis (IA) which is a fatal illness that affects a variety of immunocompromised people worldwide.
Objective: Using the lateral flow test for the detection of Galactomannan antigen in immunocompromised patients suspected to have IA.
Methods: This study was conducted on 72 patients, whose samples (serum, Bronchoalveolar lavage, Blood) were collected from the Hematology-Oncology Unit at Baghdad Teaching Hospital and Pediatric Welfare Hospital, and ICU in Ghazi AL-Hariri Surgical Specialties Hospital, Bone Marrow Transplantation Center in the period between
... Show MoreBackground: The increasing global prevalence of major depressive disorder (MDD) has become an important challenge, leading to a heightened demand for oral medicine in developed nations. This demand arises from the recognition of the association between psychiatric disorders and other conditions, including various orofacial pain disorders.
Objective: This study are to evaluate oral conditions such as recurrent aphthous ulcers, burning mouth syndrome, and altered taste and to assess salivary alpha-amylase in individuals diagnosed with major depressive disorder.
Methods: This research uses a cross-sectional study design that includes a sample of 49 patients who have been diagn
... Show Moreالخلفية: سرطان الرئة هو مرض تنمو فيه خلايا الرئة خارج نطاق السيطرة وقد ينتشر إلى الغدد الليمفاوية أو أعضاء أخرى في الجسم مثل الدماغ. قد ينتشر السرطان من أعضاء أخرى أيضًا إلى الرئتين. تبلغ فرصة إصابة الرجل بسرطان الرئة في حياته حوالي 1 من كل 15 ؛ بالنسبة للمرأة ، يكون الخطر حوالي 1 من 17. تشمل هذه الأرقام الأشخاص الذين يدخنون والذين لا يدخنون. بالنسبة للأشخاص الذين يدخنون فإن الخطر أعلى من ذلك بكثير. في جمي
... Show MoreBackground: Dutasteride, is a drug whose mechanism of action is inhibition of the enzyme 5-alpha reductase. It has been approved for use in the treatment of benign prostatic hyperplasia. Dutasteride has low solubility and high permeability, which classifies it as Biopharmaceutics classification system class II, according to the Biopharmaceutics Classification System. It has a water solubility of only 0.038 ng/mL and a slow dissolving rate, resulting in its exclusive availability in the market as a formulation contained within soft gelatin capsules.
Objective: The aim of this study involves two parts. First, is the enhancement of dutasteride dissolution rate, by the creation of dutasteride nanosusp
... Show MoreBackground: Emotional abuse is a widespread form of child abuse. It is suggested that the adverse outcomes from all forms of abuse mostly result from the emotional impacts. Resistin, a polypeptide high in cysteine, can serve as a valuable biochemical indicator of periodontal tissue damage when detected in the saliva.
Objective: To assess the relationship of emotional abuse with periodontal status and salivary resistin levels.
Patients and Methods: This cross-sectional comparative study included 522 intermediate school students aged 13-15 years in Kirkuk/Iraq. Information on emotional abuse was obtained using Glaser criteria which is a self-administered, structured, question
... Show Moreالخلفية: يمكن وصف هشاشة العظام على انه اخر مسار مشترك للعمليات التي تؤدي الى فشل المفصل . هذا المرض له أيضا تأثير اجتماعي و اقتصادي كبير على جميع الحضارات وأصبحت عبئا متزايد على عاتق الرعاية الصحية مع الشيخوخة .
اهداف البحث : الأهداف المحددة لقياس تكرار الحالات المتعلقة بكل عامل خطر مفترض من هشاشة الركبة بين عينات الدراسة وتقييم وجود علاقة سببية بين كل عامل خطر مفترض وتطور هشاشة الركب
... Show MoreBackground: Acute bronchitis, an inflammation of the lower respiratory tract characterized by an acute cough, is a prevalent clinical illness that leads patients to seek out primary healthcare services. About 5 percent of adults in the United States report having acute bronchitis annually, with 90 percent of those affected seeking medical attention.
Objectives: The study aimed to determine Nitric oxide, Procalcitonin (PCT), WBCs, neutrophils, lymphocytes, and Oxidative stress index (OSI) levels in acute bronchitis patients.
Methods: The study involved 120 volunteers aged 20–50 years old in Al-Zahra Teaching Hospital, Wasit City. 80 patients with acute bronchitis were cond
... Show Moreالتهاب المجاري البولية من الامراض الشائعة في كل العالم ويصيب النساء اكثر من الرجال. ومن الممكن ان يسبب مضاعفات اثناء الحمل وقد يؤدي الى تسمم الدم القاتل. وعليه فان الهدف من الحالة السريرية موضوع البحث هو لبيان كيف ان الخطأ في تفسير اعراض تسمم الدم ممكن ان يؤدي الى عدم علاج الحالة بالصورة الصحيحة وما يترتب عليه من نتائج طبية-قضائية. الحالة السريرية موضوع النقاش هي لأمرأة حامل حصل التهاب المجاري البولية وتمت م
... Show Moreالخلفية: ان المرضى المصابين بالعجز الكلوي المزمن والخاضعين للديلزة لفترة طويلة لهم استعداد للاصابة بمرض تصلب الشرايين وزيادة خطورة اصابتهم بأمراض قلبية وعائية.
الهدف: ان الهدف من هذه الدراسة هي لمقارنة مؤشر تصلب الشرايين العصيدي للتنبؤ بخطورة الاصابة بأمراض قلبية وعائية في مرضى العجز الكلوي المزمن والخاضعين للديلزة المنظمة وعلاقتهم بأمراض مزمنة اخرى.
المرضى وطرائق العم
... Show Moreالمقدمة: يمكن اعتبار داء السكري من النوع الاول مرض التهابي في البنكرياس , عملية موت الخلايا المبرمج الذي يحدث في خلايا ب في البنكرياس هو نتيجه التفاعل بين خلايا ت المنشطه والسايتوكين الالتهابي الانترلوكين 6 هوسايتوكين متعدد المظاهروله تاثير كبير في تنظيم الاحداث المناعيه وغير المناعيه في معظم انواع خلايا الجسم.
الهدف: قياس مستوى الانترلوكين في مصل الاطفال ال
... Show Moreالمقدمة : يعد نزف الجهاز الهضمي عند الأطفال من العلامات المنذرة التي يجب الانتباه أليها , حيث يعتبر من العلامات السريرة المنذرة للمريض وللطبيب , وبقدر ما هو مزعج بنفس الوقت فأن المسببات لنزف الجهاز الهضمي عادة تكون بسيطة ولا تشكل خطورة على حياة المريض .
أهداف البحث : لمعرفة مسببات نزف الجهاز الهضمي العلوي الأكثر شيوعا عند الأطفال , وتسليط الضوء على أهم العلامات
... Show Moreالخلفية:تطلب الدلائل الورمية في اغلب الأحيان كجزء من الأعمال التشخيصية وقد اقترح أن تركيزها العالي في المصل يدل على وجود نسيج خبيث في عضو معين ,على أية حال يستند التشخيص القطعي على تقييم تشريحي للنسيج المعين .
الهدف:إن هدف الدراسة الحالية هو تقدير قيم الدلائل الورمية CA15-3و CEA التي يمكن إن تستعمل كأداة تشخيص مبكرة في أمصال مرضى سرطان القولون , الم
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الخلفية: يتم التقليل من شأن انتشار التشوهات الخلقية عند الولادة في البلدان النامية بسبب عدم توفر الاختبارات التشخيصية في الفترة المحيطة بالولادة أو السجلات الطبية الدقيقة. قد يساعد دراسة انتشار العيوب الخلقية على وضع خط أساس ، وتتبع التغيرات بمرور الوقت ، والكشف عن القرائن المسببة.
الهدف: تهدف هذه الدراسة إلى تقييم انتشار وأنواع التشوهات الخلقية الرئيسية في أحدى المستشفيات ا
... Show Moreالخلاصة :
الخلفية: إن أحد المخاوف الصحية الرئيسية وعوامل الخطر المحتملة في جراحة القلب المفتوح هو الانتشار المتزايد للسمنة. كان الهدف من هذه الدراسة هو تقييم تأثير السمنة (مؤشر كتلة الجسم BMI ≥30 كجم/م2 ) على النتائج المبكرة بعد جراحة ترقيع الشرايين التاجية.
الطرق: على مدى 16 شهرا (فبراير 2017 الى يونيو 2018)، خضع 246 مريضا لعملية ترقيع الشرايين الت
... Show Moreخلفية البحث: استرواح الجلد هو من الأسباب الشائعة للقدوم الى ردهة الطوارئ. ولكن وجود استرواح الجلد في منطقة الرأس والرقبة نتيجة تداخل جراحي متعلق بالأسنان هو ليس عرض شائع. ووجود استرواح المنصف هو نادر جدا.
تقرير الحالة
دخلت الى ردهة الطوارئ سيده شابه تعاني من الم في الصدر وقد وجد انها تعاني من استرواح المنصف بعد قدومها من عيادة طب بالأسنان حيث قامت بعملية قلع لاحد أسنان العقل.
الخلاصة
ا
... Show Moreالمقدمة: من المرجح أن يعود مقدمو الرعاية الراضون عن الخدمات الصحية للحصول على مزيد من الرعاية وان يقوموا بالتوصية بخدمات مركز الرعاية الصحية الأولية للآخرين. مقدمو الرعاية هؤلاء عادةً ما يمتثلون لنصيحة مقدم الرعاية الطبية وخطة العلاج الموصى بها. سيؤدي الإمتثال في النهاية إلى نتائج صحية أفضل.
الأهداف: قياس رضا مقدمي الرعاية تجاه خدمات الرعاية الصحية للأطفال دون سن الخامسة في مراكز ال
... Show MoreBackground:
Background: Squamous carcinoma accounts for majority of esophaged cancinoma Most patients with esophaged cancer are middle aged or elderly with make to female ratio 2.5:1.
Aim of study : to present a fairly representative picture of the carcinoma of esophagus in' yemen.
Patients& Methods: Seventy-six patients were treated for carcinoma of esophagus over a 5 - year period by cardiothoracic and vascular surgeon working in Sana a - Yemen. Amongst them there were thirty one men and forty-five women, with male/female ratio 1:1.45, age incidence (range 38 - 40year).
Results:. Adenocarcinoma was 65% of cases and other 35% was squamous cel! carcinoma. The major risk factors were founded chewing quat, silicon particles, thermal injur
الخلاصة : في هذه الحالة المسجلة نناقش قضية اساسية يجب ان تؤخذ بنظر الاعتبار و تتعلق بالتحاليل الجينية السريرية في حقل الصرع. تحديد الجينات التي تؤثر على خطورة الصرع لها تداعيات بالغة الاهمية لكل من الابحاث و التدريب السريري. في مجال الابحاث, المعلومات المستحصلة تؤدي الى تطوير علاجات جديدة تستهدف ميكانيكيات محددة او طرق لمنع قابلية الاصابة بالصرع. في التدريب السريري, استعمال المعلومات
... Show MoreBackground: To determine the DNA content in subfertile patients and to correlate it with seminal sperm concentration.
Design: Prospective observational study.
Setting: College of Medicine, Dept. of Physiological chemistry and Institute for embryo Research and infertility treatment-University of Baghdad.The study was conducted
through years 2004-2005.
Methods: A random sample of 61 subfertile male patients undergoing semen evaluation and aged from 20-45 years were studied. Semen samples were assessed for seminal sperm
concentration microscopically and were classified into 3 different groups according to count (million/ml).Then sperm D N A content (μg/ml) was estimated using a microchemical
spectropho
Background: uterine involution is the process by which the postpartum uterus returning to its prepregnant state by the process of autolysis. The aim of the study is to fallow the uterine involution sonographicly during the first two weeks of puerperium and clinical correlation of several puerperal conditions was sought.
Patients and methods: One hundred full term women were delivered in one of Baghdad hospital during a six month period were followed by serial sonogram during the first two weeks of the puerperal period to show the normal process of uterine regression in relation to several condition .The rate of uterine involution were shown as percentage drop in uterine volume at day (7) and day (14) 
Background: Otitis media with effusion(OME)is a common cause of deafness in children with subsequent impairment of speech development and scholastic difficulties.Treatment
remains controversial.
Aim: To study the effect of amoxicillin-clavulanate in treatment of OME
Patients and methods: A prospective study of a target sample consisting of sixty children under the age of 12 years presented with chief complaints duration for at least 6 weeks and
on examination there were bilateral red and retracted tympanic membranes without oversized adenoids and no underlying causes require surgical correction e.g cleft palate.The
patients were divided into two groups;group A which received Actifed for 4 weeks and grou
Background: Male infertility is a multifactorial condition influenced by various physiological and biochemical factors. Seminal fluid composition plays a crucial role in sperm function and fertilization potential. Chitotriosidase is a chitinase enzyme released by activated macrophages and is highly conserved and controlled. The notable chitinase in humans plays a significant role in the body's immunological response and is linked to inflammation, infection, tissue damage, and remodeling processes. On the other hand, malondialdehyde is a marker of lipid peroxidation, reflecting oxidative stress levels.
Objective: This study aimed to explore the correlation between malondialdehyde levels and Chitotr
... Show MoreBackground: Psoriasis is an immune-mediated inflammatory disease with unknown aetiology that may be associated with the defect in proliferation and differentiation of the keratinocytes related to inflammatory cell infiltration. According to published reports, it is universal in occurrence; its prevalence in different populations varies from 0.1% to 11.8%. Receiving Apremilast resulted in a strong reduction in interleukin 17 and interleukin 23, as well as reduced expression of other inflammatory cytokines and improvement of psoriatic lesions.
Objectives: This study aimed to assess the impact of Apremilast on levels of IL-17, IL-23, and lipids in obese psoriatic patients.
Methods: Thirty obe
... Show MoreBackground: Hodgkin’s Diseases is a group of cancers characterized by Reed- Sternberg cells, aneuoploid cells that usually express CD15 and CD30. Several epidemiological and serological studies support the role of Epstein –Barr virus in the pathogenesis of Hodgkin’s Diseases
Patients and Method: A retrospective study was done where by twenty cases were collected from the Pediatric Oncology Clinic in AL-Kadhyimia Teaching Hospital over a period of five years from the first of January 2002 – end of December 2006.Information was taken from the patient’s records in the Pediatric Oncology Clinic including age at presentation, sex, physical finding, histopathological subtypes, staging , treat
... Show MoreBackground: Human Cytomegalovirus (HCMV) infects a wide range of human cells, including colonic epithelial cells that give rise to adenomas and adenocarcinomas. Persistent productive infection of tumor cells is essential for oncomodulation by HCMV.This study aimed to detect HCMV matrix protein using in situ hybridization technique (ISH) in colorectal adenocarcinoma compared to normal colon tissues, and to the presence of cytomegalovirus inclusion bodies in infected colorectal carcinomas.
Patients and methods: Twenty six of colorectal adenocarcinomas were obtained in paraffin-blocks compared to 10 normal colon specimens which were age and sex matched as control group. Detection of HCMV was obtained by in s
Background: Decreased taste acuity to the four basic tastes is closely related to health problems (diseases & medications), aging, and smoking. This study aimed to determine taste detection and recognition thresholds to the four basic tastes in some physiological and pathological conditions, determine saliva flow rate, serum and saliva zinc levels in these groups.
Objective and Methods: The study includes 218 individuals (35–80) years old divided into six groups; the control, aging (subjects over 60 years), smokers, diabetics, haemodialysis patients and hypertensive patients on chronic use of captopril.The taste detection and recognition thresholds of sweet, salty, sour and bitter tastes, saliva flo
Background: Several biological factors such as bacterial infections and immunological status are implicated in predisposing individuals to bladder cancer. Bacterial infection of urinary tract has been related to increase the risk of bladder cancer.
Patients and Methods: Resected tumors of a total of 73 patients were obtained under sterile surgical conditions. Biopsy processing samples and culture procedures of biopsy samples were mentioned in the text.
Results: Bacterial growth was observed in 48 biopsy tissues of those patients represent (65.8%) while, 25(34.2%) yielded no growth (negative results). It is obvious that E. coli is the most predominant organisms followed by K. pneumoniae and Ps. Aer
Background: Bronchogenic carcinoma is considered one of the most common malignant diseases that affects both sexes. The radiological profile of bronchogenic cancer can prove to be of great assistance in the management of this disease.
Objectives: The current study aimed to assess a radiological profile for bronchogenic carcinoma in a sample of Iraqi patients.
Methods: A cross-sectional study that comprised a total of 100 patients affected with bronchogenic cancer in Al-Imamain Al-Kadhimain Medical City, Baghdad, Iraq, from the 1st of January to 31st of July 2020. Clinical characteristics, diagnostic modalities, the site of the tumor with
Background: There were definite changes in pathologies involving thyroid gland allover the world with increasing incidence of thyrotoxicosis and differentiated malignancies.
Patients and methods: 224 patients were operated upon by the same surgeon during 15 years period. Those patients were divided into two groups (GI from June 1990 up to June 2000) and (GII from June 2000-June 2005).
Results: female to male ratio was 3.3:1. The most common presentation among both groups was Multinodular goiter (MNG) 76.8%. toxic goiter was recorded in 24% of patient with increase among GII patients. A significant effect of stress on the increasing incidence of thyrotoxicosis was elicited in more than 50% of patients w