We described herein the synthesis of novel bis-1,3,4-oxadiazole containing glycine moiety. N-{5-[5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-yl-sulfanyl]-1,3,4-oxadiazole-2-yl-methyl}-4methoxybenzamide was fully characterized by elemental analysis, FT-IR and 1H NMR spectroscopy. Also this study was designed to show the effects of bis-oxadiazole compound on the activities of some transferase enzymes such as: GOT, GPT and γ-GT in sera. This compound demonstrated activation on GOT and GPT activities, inhibitory effects on the γ-GT activity. These effects increased with the increasing of the concentration of the compound. The causes of the increases and decreases in the enzymes activities are discussed

  Interleukin -33 is a new member of the IL-1 superfamily of cytokines that is expressed mainly by stromal cells.Its expression is upregulated following pro-inflammatory stimulation. Aim of the present study was to assess the serum IL-33 level and its relationship with inflammatory biomarker CRP  in Iraqi females patients with celiac disease.  Thirty five patients with celiac disease (CD)  and thirty healthy individuals as control group  were enrolled in this study,their age ranged (20-35) year.Anti-Gliadin IgA ,IgG and Anti-Tissue IgA ,IgG were estimated in all subjects as  diagnostic parameters .ESR and CRP were assayed as inflammatory biomarkers. IL-33 was determined in patients and control groups. 

The study's goals were to separate and identify endophytic fungi from Aloe vera leaves by looking at their morphology and molecules, as well as to find the chemical compounds in the leaf extract by using HPLC, GC, and GC-Mass instruments. The results showed that 53 endophytic fungi were isolated from a total of 120 pieces of A. vera leaves, with a total colonization rate of 44.16%. The fungus Aspergillus terreus had a colonization rate of 14.16%; Aspergillus niger had a colonization rate of 13.33%; Penicillium chermesinum demonstrated a colonization rate of 6.66%; Paecilomyces variotii had a colonization rate of 2.5%; Talaromyces radicus; and Aspergillus flavus achie

The research study included the synthesis of a new series of heterocyclic derivatives containing the antibiotic Levofloxacin. The first way provides for the reaction of  Levofloxacin with thionyl chloride in benzene as a solvent to give an acid chloride derivative. A new class of acid hydrazide synthesized from Levofloxacin was studied. Schiff bases were produced via the reaction of acid hydrazide with substituted aromatic ketones in methanol. The next stage involved the response of Schiff bases with thioglycolic acid and mono chloroacetic acid in DMF to produce derivatives of the antibiotic levofloxacin that have five heterocyclic members, including the derivatives thiazolidine-4-one and oxazolidine-5-one. The FTIR, ¹HNMR, a

  Diabetes Mellitus (DM) is a chronic disease distributed worldwide and dominantly related to different types of diseases especially microbial infections, this study aimed to find the relationship between DM mouth microbiome and some demographic factors. Sixty saliva specimens and bacterial oral swabs were collected from randomly selected DM patients, including 29 females and 31 males enrolled in this study, which was obtained from the Al-Mustansiriya University national diabetes center in Baghdad, and other 40 apparently healthy people specimens and swabs were collected from 25 females and 15 males as a control group for the period starting November / 2021 to February / 2022. The results revealed that the most prevalent bacterial gener

Most dental supplies don't seem to be much of a barrier against germ infiltration. Therefore, the filling must be done with perfect caution and high antimicrobial effectiveness. When dental erosion occurs due to germs that lead to caries, a dental filling is used, creating a small microscopic space between the dental filling and the root end infiltration. This allowed the tooth to be penetrated for the second time, which was the research problem. Adding two compounds to antibacterial fillers (zinc polycarboxylate cement) made them work better: Firstly, was zinc oxide  (ZnO) that was made chemically, and secondly, was green ZnO nanoparticles that were made from orange peels and mixed with ZPCC in different amounts. The study was conducte

Truncated distributions arise naturally in many practical situations. It’s a conditional distribution that develops when the parent distribution's domain is constrained to a smaller area. The distribution of a right truncated is one of the types of a single truncated that is restricted within a specific field and usually occurs when the specified period for the study is complete.  Hence, this paper introduces Right Truncated Inverse Generalized Rayleigh Distribution (RTIGRD) with two parameters  is introduced. Then, provided some properties such as; (probability density function, cumulative distribution function (CDF), survival function, hazard function, ‎rth moment, mean,   variance, Moment Generating Function, Skewness, kurtosi

The essential objective of this paper is to introduce new notions of fibrewise topological spaces on D that are named to be upper perfect topological spaces, lower perfect topological spaces, multi-perfect topological spaces, fibrewise upper perfect topological spaces, and fibrewise lower perfect topological spaces. fibrewise multi-perfect topological spaces, filter base, contact point, rigid, multi-rigid, multi-rigid, fibrewise upper weakly closed, fibrewise lower weakly closed, fibrewise multi-weakly closed, set, almost upper perfect, almost lower perfect, almost multi-perfect, fibrewise almost upper perfect, fibrewise almost lower perfect, fibrewise almost multi-perfect, upper^* continuous fibrewise upper^∗ topol

Synthesis of new ligand, namely [bis(2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl) hydrogen borate] (BIB), utilizing the reaction of metronidazole with boric acid in mole ratio (2:1), as well as the metal complexes with [Ni(II) and Cu(II)], were synthesized. All synthesized compounds were characterized by utilizing spectroscopic techniques such as FTIR, 1H-NMR, thermal analysis (T.G., UV-Vis), and atomic absorption (A.A.S.), as well as micro elemental analysis (C.H.N.), melting point (m.p), magnetic susceptibility, molar conductivity, and chloride content measurements. All complexes were paramagnetic, and the electrolyte and the suggested geometries were tetrahedral for nickel and octahedral for copper. In addition, all the transition meta

Background: Polycystic ovarian syndrome (PCOS) is the most endocrine disorder common effect (5-10) % in women at reproductive age. Thyroid dysfunction with PCOS is both representing parts of the endocrine system; this link leads to problems of ovulation and pregnancy.  Aims: to investigate the prevalence of thyroid disorder in PCOS woman, and associate the outcome with obesity. Patient and method: This study was conducted in Al-batol Teaching Hospital in Baquba City /Iraq. The results reviewed included 63 women: 45 PCOS were diagnosed on the basis of Rotterdam criteria, 18 as control, aged 17- 44 year. The samples have been collected at second day of menstrual cycle, to test fT3, fT

          In this paper, the survival function has been estimated for the patients with lung cancer using different parametric estimation methods depending on sample for completing real data which explain the period of survival for patients who were ill with the lung cancer based on the diagnosis of disease or the entire of patients in a hospital for a time of two years (starting with 2012 to the end of 2013). Comparisons between the mentioned estimation methods has been performed using statistical indicator mean squares error, concluding that the estimation of the survival function for the lung cancer by using pre-test singles stage shrinkage estimator method was the best   . <

       Current study obtained (75) isolate of Pseudomonas aeruginosa collected from different cases included : 28 isolates from otitis media, 23 isolates from burn infections, 10 isolates from wound infections, 8 isolates from urinary tract infections and 6 isolates from blood, during the period between 1/9/2014 to 1/11/2014

       The result revealed that the tox A gene was present in 54 isolates (72%) of Pseudomonas aeruginosa. The gel electrophoresis showed that the molecular weight of tox A gene was 352 bp. The result shows 17 isolates (60.71%) from otitis media has tox A gene, 1

     In this paper, the maximum likelihood estimator and the Bayes estimator of the reliability function for negative exponential distribution has been derived, then a Monte –Carlo simulation technique was employed to compare the performance of such estimators. The integral mean square error (IMSE) was used as a criterion for this comparison. The simulation results displayed that the Bayes estimator performed better than the maximum likelihood estimator for different samples sizes.

      In this paper, we introduced module that satisfying strongly -condition modules and strongly -type modules as generalizations of t-extending. A module  is said strongly -condition if for every submodule of  has a complement which is fully invariant direct summand. A module   is said to be strongly -type modules if every t-closed submodule has a complement which is a fully invariant direct summand. Many characterizations for modules with strongly -condition for strongly -type module are given. Also many connections between these types of module and some related types of modules are investigated.

This paper focus on study the variations of monthly tropospheric NO₂ concentrations over three Iraqi cities Baghdad (33.3° N, 44.4° E), Basrah (30.56° N, 47.8° E) and Erbil (36.3° N, 44.06° E). Monthly NO₂ retrievals from the Ozone Monitoring Instrument (OMI) onboard Aura satellite during the period from October 2004 to March 2013 have been used.  The results show a high monthly and annual NO₂ concentrations at Baghdad than Basra and Erbil may be attribute to high densely populations and a high economic activity. During the whole period, Baghdad, Basrah and Erbil were exhibited an average of NO₂ (8.1±2.5), (3.7±1.3) and (3.3±1.7) in unit 10¹⁵ molecules

        A new speed and sensitive batch and merging zones-flow injection analysis spectrophotometric ways for estimation of captopril in a fine material and in pharmaceutical formulations were suggested. The procedure was depended on the  decline of Fe(III) as FeCl₃ to Fe(II) by captopril in acetic acid as medium, the produced Fe(II) interplays with 1,10-phenanthroline to compose a soluble orange-red colored product that is determined at maximum wave length of 511nm. The manifold FIA system was able to determine of CPL. with a throughput 51 sample/h. Calibration curves of absorbance against concentration sign of that Beer^, s law is submitted to within the concentration scale o

     Flucloxacillin (Flx) derivative metal complexes(2S,5R,6R)-6-({[3-(2-chloro-5-fluorophenyl)-5-methylisoxazol-4-yl] carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo [3.2.0] heptane-2-methyl aster and proline with CoII, NiII, CuII, ZnII and CdII. They were synthesized and identified using physicochemical techniques, including elemental analysis CHNS, metal analysis AA, Uv-Vis, FTIR, TGA, magnetic susceptibility, and conductivity measurement. This study aims to investigate the coordination behavior of flucloxacillin and proline, analyze their structural and electronic properties, and evaluate their potential biological activities against bacterial and fungal strains. Additionally, theoretical calculations usin

Sodium thiosulfate (STS) is a possible therapeutic candidate molecule in a range of diseases and drug-induced toxicities due to its antioxidant, anti-inflammatory, and anti-apoptotic capabilities. The current study aimed to find the effective dose of STS in adult male rats given nicotine by evaluating serum MDA and blood partial pressure of oxygen (PO₂) levels. Thirty-six adult male Wistar rats, Rattus norvegicus (weighing 190–220 g) with an age of 3–3.5 months,  were chosen randomly and separated into six equal groups, administered for 28 days. Animals in the control group were administered an intraperitoneal (i.p.) injection of normal saline, while those in groups 1, 2, 3, 4, and 5 received repeated doses of an

Although considered a good alternative to organophosphate pesticides, there are reports indicating adverse effects of neonicotinoid insecticides on reproduction. The present work was designed to determine the chronic effects of orally administered for treated with 20 mg/kg/b.w. of imidacloprid pesticides and treated with 20 mg/kg/b.w. of nano-imidacloprid on biochemical blood profile in male rats for a duration of 60 d. Result: the exposure caused a significant decline in red blood cells (RBCs) and hemoglobin (H.b.) in all treated groups compared with the control, while causing an increase in blood platelets (PLT) and white blood cells (WBCs) in all rats treated as compared with the control rats. Furthermore, oxidative stress parameters

        The goal of this work, is to examine the concept of a double centralizer, and double Jordan centralizer on prime and semiprime Г-rings, this is done by studying examples, remarks and results related to that concepts and looking for the conditions under which T equal S, we prove the results, the first result, let A be a semiprime Γ-ring and T is a left centralizer, S is a right centralizer, and they fulfilling x  T(y) = S (x)  y,  for each x  A,    Γ, thence (T,S) is a double centralizer. The second, let A be a prime Γ-ring, U be a not equal zero ideal of A, such that, T is a left centralizer, S is a right centralizer, and fulfilling x T(y) = S (x)  y, for each x,

Antibiotic resistance has dramatically increased among UTI patients with UPEC infections. They are crucial to the pathophysiology of UTIs because UPEC invades the bladder through a variety of virulence factors. Afa adhesins are produced by human-derived Echerichia coli and have been shown to bind to the (DAF, CD55) as a receptor, while Yqi adhesin recreates a denotative role in colonization, the initial stage of pathogenesis, during infection with E.coli . E.coli isolates from 200 urine samples of credible UTI patients were detected. By employing different media, VITEK, and the biochemical identification. Susceptibility to the Ciprofloxacin antibiotic was established by using the disc diffusion approach, while

Using B-cubic spline base, the numerical solutions of optimal control of dynamical systems of fractional-order have been examined. In order to determine the dynamical system's control function through time whilst optimizing an objective optimal function. There are numerous applications for the optimal control system in science, engineering and the one branch of applied mathematics operations research. The primary goal of this study is to approximate the numerical solutions for a fractional-order optimal control systems in both free and non-free terminal time (TT). The collocation approach considers a numerical solution to this problem by using a B-cubic spline base. A numerical comparison has been introduced between the analytical soluti

     Novel heterocyclic acid-base indicators 8-[3-(phenol)azo] theophylline (PAT) and 8[1-(6-sulfonic acid naphthalene) azo] theophylline (SAT) were synthesized through the reaction between m-amino phenol and 1-amino naphthalene -6-sulfonic acid with sodium nitrite to form the diazonium salt at a temperature 0-5˚C in an acidic medium, then a coupling process between the diazonium salt and theophylline compound to produce pigments at the same temperature while maintaining the PH level at 5-6. This study aims to prepare acid-base indicators based on azo dyes. The structural features of these indicators were examined via elemental analyses [FTIR, UV-Vis, and HNMR] spectroscopies, thermal analysis (TGA), and scanning el

In this present study, a clinically isolated of Pseudomonas spp. from a variety of sources, such as burn patients, wound infections, and UTI patients, that can produce melanin pigment in the presence of 2 % L-tyrosine in both liquid and solid media. These bacteria were identified as Pseudomonas aeruginosa based on morphological, biochemical, and VITEK-2 compact system analysis. The higher melanin producer isolate Ps81, which produces melanin at rate of 3.018933 µg/ml, has been chosen for further investigation steps. The pigment was extracted by several steps of alkali dissolving and acid precipitation followed by washing with organic solvents. Chemical analysis of the pigment particles revealed that they were acid resistant, al

In response to the water crisis, further research is necessary to comprehend the impact of human activities on nutrient concentrations in aquatic ecosystems, building on the extensive studies already conducted to understand these impacts on the water quality of various aquatic ecosystems. We hypothesized that human activities in the Tigris River's catchments could alter the nutrient concentrations in the water along the river. The results showed that phosphate concentration differed significantly among the studied sites due to distributed human activities, while nitrate concentration did not. Water temperature did not affect phosphate and nitrate concentrations. We concluded that human activities on the surrounding landscapes could be mo

Graphene-carbon nitride can be synthesized from thiourea in a single step at a temperature of four hours at a rate of 2.3 ℃/min. Graphene-carbon nitride was characterized by Fourier-transform infrared spectroscopy (FTIR), energy dispersive X-ray analysis (EDX), scanning electron microscopy, and spectrophotometry (UV-VIS). Graphene-carbon nitride was found to consist of triazine and heptazine structures, carbon, and nitrogen. The weight percentage of carbon and the atomic percentage of carbon are 40.08%, and the weight percentage of nitrogen and the atomic percentage of nitrogen are 40.08%. Therefore, the ratio and the dimensions of the graphene-carbon nitride were characterized by scanning electron microscopy, and it was found that the

Supra nanoparticles (submicron) of Chicken bones fibers were used (before and after treated with citric acid solution) as additives  to dental composite with the weight ratios (1%, 2% and 4%). The main mechanical tests represented by hardness, wear resistance and compression strength was carried out on the improvement dental composites.

The addition of treated supra nanoparticles Chicken thigh bones with particles size (300 nm) by weight ratio (1%) to ordinary dental composite resin , significantly improves all of its mechanical properties, in addition to the increase the value of the its  glass transition temperature from  43^oC  to 45.4 ^oC. The techniques X-ray diffraction (XRD), Energy Dispersive Spectr

This research is considered the first of its kind in this sector of the river for more than three decades and aims to evaluate the diversity, abundance, richness and spatiotemporal variations of Cladocera within Samarra Impoundment water. The samples of these crustaceans were collected from three sites in the impoundment every two months between February 2023 and December 2024. We identified 19 taxa belonging to five Cladocerian families. The most abundant genera were Alona sp., Bosmina sp., Chydorus sp., Ceriodaphnia sp., Diaphanosoma sp., Daphnia sp. and Moina sp. The minimum and maximum densities were observed in spring and winter, respectively. The average values for even

The emphasis of the world on sustainable water quality and frequent monitoring of pollutants has grown greater to protect public health and biodiversity, aimed at limiting human activities that lead to water pollution and conserving water resources. The objective of this study was to evaluate the levels of pollution and concentrations of different heavy metals in sediment and water samples taken from four locations along the Tigris River at Baghdad City, Iraq, during 2024. In order to investigate the variations in conditions between the wet and dry seasons, samples were collected during each. Among the elements under analysis were lead, nickel, chromium, zinc, and iron. The samples were analyzed for heavy metals using Atomic Absorption S

This study used wild barbines  (Bacopa Monnieri)  to control the southern cowpea beetle (Callosobruchus maculatus) and their effects on cowpea beetle eggs. Alcoholic extracts and nanocapsules were used at different concentrations, with the alcohol extract being 1000, 2000, and 3000 PPM. Eight out of ten eggs were unhatched, and two hatched, indicating that the 3000 concentrations had the highest egg toxicity rate. Regarding saponins at the same concentrations, the 3000 concentrations had the best results, whereas the 1000 and 2000 concentrations produced poorer results. Additionally, it was discovered that saponins had a stronger effect than terpenes. The nanocapsule concentrations that affected the Callosobruchus maculatus beetle's eg