Sulfamethoxazole and its derivatives are commonly utilized in the pharmaceutical and medicinal industry due to their biological and pharmaceutical activities, including anti-tubercular, anti-fungal, anti-cancer, anti-bacterial, and herbicidal activities. This review presents the latest and most promising studies related to synthesizing organic derivatives of sulfamethoxazole and their drug-metal complexes and the biological activity associated with these complexes. Some organic drugs, including sulfamethoxazole, exhibit toxicological and pharmacological properties that can be administered in the form of metal complexes. Many researchers have synthesized organic ligands derived from sulfamethoxazole in the forms of Sc

We conducted a study on the quality of non-diatom planktonic algae in the Tigris River during the autumn 2022 and winter 2023 seasons. The study focused on the impact of the medical city waste discharge to the Tigris River at three sites: Al-Sarafiya Bridge in the north, Medical City, and the Bab Al-Mu'adam Bridge in the south of Khader Elias. The study also examined some physical and chemical variables of the river water. Findings showed that there are 74 species (38 genera) of non-diatom algae in four orders. The blue-green algae Cyanophyceae and Chlorophyceae had the most species, with 35 species belonging to 19 genera and 16 genera per division, or 47% of all algae. Euglenophyceae had 5%, with 3 species and 2 genera, and Chrysophycea

     Due to superficial particles and remarkable packing technologies, the HALO-HILIC column outperformed regular porous columns in terms of analysis time. This study analyzes and identifies kaempferol and luteolin flavonoids in natural herbs. A fast, novel chromatographic method combining superficially porous silica particles packed in a column served as the separation tool for hydrophilic interaction liquid chromatography coupled with a UV detection system is being introduced in this work. Flavonoid separation and quantification took six minutes using only superficial porous particles in the HILIC column compared to hours using fully porous particles in the RP columns. The findings demonstrated that the HILIC mode

     Novel heterocyclic acid-base indicators 8-[3-(phenol)azo] theophylline (PAT) and 8[1-(6-sulfonic acid naphthalene) azo] theophylline (SAT) were synthesized through the reaction between m-amino phenol and 1-amino naphthalene -6-sulfonic acid with sodium nitrite to form the diazonium salt at a temperature 0-5˚C in an acidic medium, then a coupling process between the diazonium salt and theophylline compound to produce pigments at the same temperature while maintaining the PH level at 5-6. This study aims to prepare acid-base indicators based on azo dyes. The structural features of these indicators were examined via elemental analyses [FTIR, UV-Vis, and HNMR] spectroscopies, thermal analysis (TGA), and scanning el

  This study employed the biosynthetic technique for creating vanadium nanoparticles (VNPs), which are affordable and user-friendly; VNPs was synthesized using vanadium sulfate (VOSO₄.H₂O) and a plant extract derived from Fumaria Strumii Opiz (E2) at a NaOH concentration of 0.1 M. This study aims to investigate the potential applications of utilizing an adsorbent for metal ions to achieve environmentally friendly production and assess its antibacterial activity and cytotoxicity. The reaction was conducted in an alkaline environment with a pH range of 8–12. The resulting product was subjected to various characterization techniques, including Fourier transform infrared spectroscopy, ultraviolet-visible spe

It was collected 145 samples from a variety of clinical sources, including urinary tract infections, wounds, blood, respiratory tract infections, stool, sputum, and high vaginal swabs, from various hospitals in Baghdad. Following the collection, we conducted microscopic examinations, biochemical examinations, and diagnosis. The Vitek-2 Compact System conducted the final analysis. It was gotten 50 isolates of Escherichia coli, and 34% of those were from urinary tract infections, wounds, respiratory system infections, sputum, and vaginal swabs. 72% of the isolates were from urinary tract infections, 14% were from wounds, and 2% were from respiratory system infections. Next, we conducted genotyping and tested for beta-lactamase res

Time-delay differential equations-based mathematical modeling is a significant tool for understanding the effect of delay in biological systems and analyzing how it affects the dynamics of those systems' asymptotic behavior. The prey-predator model described in this paper includes disease in the prey species, harvesting in each population, and time delays in predation and gestation of the predator. The solutions of the model are positive and bounded for all times within a realistic region. The existence of all fixed points has been established. When a time delay is present, the essential requirements for the local stability of the positive equilibrium and the occurrence of Hopf bifurcation can be determined by analyzing the associated ch

The effect of couple stress, slip condition, changing rotation, and other variables on the peristaltic flow of Powell-Eyring fluid in an inclined asymmetric channel with an inclining magnetic field through a porous media is investigated in this study. Constitutive equations obeying the Powell-Eyring fluid model are employed. In flow analysis, assumptions such as a low Reynolds number and a long wavelength approximation are used. The stream function and mechanical efficiency have closed form expressions devised. The stream function is expressed mathematically. Through the collection of figures, the impact of various criteria is explained and graphically represented Through the collection of figures, the impact has been explained of the Ha

An inherited tendency is necessary for the manifestation of celiac disease (CD), an autoimmune, gluten-sensitive, inflammatory disorder of the small intestine. Gluten, a storage protein in cereals, causes CD. An increase in oxidant compound generation, surpassing the capacity of the endogenous antioxidant system, causes oxidative stress (OS). This study aims to evaluate some oxidants and antioxidants factors in Iraqi females with CD. This hospital-based cross-sectional study at Baghdad Educational Hospital in Baghdad, Iraq, involved 100 female participants of reproductive age. Tests have been measured, such as total oxidants (TOS), total antioxidants (TAS), malondialdehyde (MDA), catalase (CAT), nitric oxide (NO), total protein (TP), and

     Antibacterial substances belong to a group of compounds that attack dangerous microorganisms. Therefore, killing bacteria or reducing their metabolic activity will lessen their adverse effects on a biological system. They originated from either synthetic materials, microbes, or mold. Many of these medications treat the gram-negative bacteria from the critical precedence group, such as Pseudomonas, carbapenem-resistant Acinetobacter, and Enterobacterales. This study aims to investigate the simultaneous analysis of specific antibacterial spectrophotometrically. The WHO maintains this list of priority infections with antibiotic resistance. Drug combinations in single dosage forms are becoming increasingly popular in the pharmaceuti

Periodontitis is a common disorder caused by imbalanced plaque biofilms and associated with gradual deterioration of the teeth supporting apparatus. Obesity is documented as a significant health concern and considered a primary risk factor for the progression of many diseases, such as hypertension, diabetes, malignancies, and periodontitis. Proinflammatory cytokines released in response to these health conditions are of great importance and establish the link between diagnosis and treatment. The present study was conducted to assess levels of chemerin and visfatin in saliva and to evaluate the impact of obesity on periodontitis. Ninety participants were included in the study and dived into three groups: (Group I: obese and periodontitis

Sodium thiosulfate (STS) is a possible therapeutic candidate molecule in a range of diseases and drug-induced toxicities due to its antioxidant, anti-inflammatory, and anti-apoptotic capabilities. The current study aimed to find the effective dose of STS in adult male rats given nicotine by evaluating serum MDA and blood partial pressure of oxygen (PO₂) levels. Thirty-six adult male Wistar rats, Rattus norvegicus (weighing 190–220 g) with an age of 3–3.5 months,  were chosen randomly and separated into six equal groups, administered for 28 days. Animals in the control group were administered an intraperitoneal (i.p.) injection of normal saline, while those in groups 1, 2, 3, 4, and 5 received repeated doses of an

Although considered a good alternative to organophosphate pesticides, there are reports indicating adverse effects of neonicotinoid insecticides on reproduction. The present work was designed to determine the chronic effects of orally administered for treated with 20 mg/kg/b.w. of imidacloprid pesticides and treated with 20 mg/kg/b.w. of nano-imidacloprid on biochemical blood profile in male rats for a duration of 60 d. Result: the exposure caused a significant decline in red blood cells (RBCs) and hemoglobin (H.b.) in all treated groups compared with the control, while causing an increase in blood platelets (PLT) and white blood cells (WBCs) in all rats treated as compared with the control rats. Furthermore, oxidative stress parameters

        The goal of this work, is to examine the concept of a double centralizer, and double Jordan centralizer on prime and semiprime Г-rings, this is done by studying examples, remarks and results related to that concepts and looking for the conditions under which T equal S, we prove the results, the first result, let A be a semiprime Γ-ring and T is a left centralizer, S is a right centralizer, and they fulfilling x  T(y) = S (x)  y,  for each x  A,    Γ, thence (T,S) is a double centralizer. The second, let A be a prime Γ-ring, U be a not equal zero ideal of A, such that, T is a left centralizer, S is a right centralizer, and fulfilling x T(y) = S (x)  y, for each x,

In this present study, a clinically isolated of Pseudomonas spp. from a variety of sources, such as burn patients, wound infections, and UTI patients, that can produce melanin pigment in the presence of 2 % L-tyrosine in both liquid and solid media. These bacteria were identified as Pseudomonas aeruginosa based on morphological, biochemical, and VITEK-2 compact system analysis. The higher melanin producer isolate Ps81, which produces melanin at rate of 3.018933 µg/ml, has been chosen for further investigation steps. The pigment was extracted by several steps of alkali dissolving and acid precipitation followed by washing with organic solvents. Chemical analysis of the pigment particles revealed that they were acid resistant, al

In response to the water crisis, further research is necessary to comprehend the impact of human activities on nutrient concentrations in aquatic ecosystems, building on the extensive studies already conducted to understand these impacts on the water quality of various aquatic ecosystems. We hypothesized that human activities in the Tigris River's catchments could alter the nutrient concentrations in the water along the river. The results showed that phosphate concentration differed significantly among the studied sites due to distributed human activities, while nitrate concentration did not. Water temperature did not affect phosphate and nitrate concentrations. We concluded that human activities on the surrounding landscapes could be mo

     Flucloxacillin (Flx) derivative metal complexes(2S,5R,6R)-6-({[3-(2-chloro-5-fluorophenyl)-5-methylisoxazol-4-yl] carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo [3.2.0] heptane-2-methyl aster and proline with CoII, NiII, CuII, ZnII and CdII. They were synthesized and identified using physicochemical techniques, including elemental analysis CHNS, metal analysis AA, Uv-Vis, FTIR, TGA, magnetic susceptibility, and conductivity measurement. This study aims to investigate the coordination behavior of flucloxacillin and proline, analyze their structural and electronic properties, and evaluate their potential biological activities against bacterial and fungal strains. Additionally, theoretical calculations usin

     Doxycycline is one of the tetracycline-class antibiotics used to treat bacterial and protozoan infections. The development method aimed to determine the Doxycycline hyclate in pharmaceutical drugs using a novel, rapid, and sensitive colorimetric-flow injection approach. The adopted method depended on forming a purplish violet colour complex for the doxycycline hyclate-ammonium chloroaurate reagent in an alkali medium, which a homemade SFI Analyzer measured. Both the physical and chemical variables were analyzed and improved. The calibration plot was linear in the 5-70 μg.mL-1 for the green light source, with a correlation coefficient r=0.9976 using the peak height of green light. The limit of detection was 0.5

     Melatonin (Mel) is a conserved chemical that has been found in far-removed evolutionary organisms. Additionally, it has been proposed that Mel is a stand-alone plant growth regulator whose action is presumably similar to that of IAA and may moderate the effects of other plant growth regulators. Twelve medicinal herbs were divided into parts, and their melatonin concentrations were measured. These plants Ziziphus spina-christi, , Eucalyptus comaldulensis, Melissa officinalis,  Alhagi maurorum, Lavandula angustifolia, Vitex agnus-sactus, Piper nigrum, Hordeum vulgare, Matricaria chamomilla, Borago  officinalis, Solanum lycopersicum and Citrus aurantium  . Methanol was used to extract melatoni

The aim of this paper is to find the inequivalent k-sets in the finite projective line of order thirty-two, PG(1,32). The number of projectively distinct 4-set is five and all of them are of type N(neither harmonic nor equianharmonic). The k-sets, k=4,…,11 have been done, where the number of projectively distinct are 5,11,53,148,481,1240,2964,6049, respectively. The k-sets k=12,..,17 classified depending on the projectively distinct 11-sets whose have non-trivial subgroups only, where the numbers of projectively distinct are 493,5077,2583,288,2412,697. The stabilizer group of each k-sets is computed. The kind of groups that computed for the k-sets are I, Z_2, Z_3, V_4, S_3, Z_2×Z_2×Z_2, Z_2×Z_2×Z_2×Z_2 and the large group is the d

Antibiotic resistance has dramatically increased among UTI patients with UPEC infections. They are crucial to the pathophysiology of UTIs because UPEC invades the bladder through a variety of virulence factors. Afa adhesins are produced by human-derived Echerichia coli and have been shown to bind to the (DAF, CD55) as a receptor, while Yqi adhesin recreates a denotative role in colonization, the initial stage of pathogenesis, during infection with E.coli . E.coli isolates from 200 urine samples of credible UTI patients were detected. By employing different media, VITEK, and the biochemical identification. Susceptibility to the Ciprofloxacin antibiotic was established by using the disc diffusion approach, while

Using B-cubic spline base, the numerical solutions of optimal control of dynamical systems of fractional-order have been examined. In order to determine the dynamical system's control function through time whilst optimizing an objective optimal function. There are numerous applications for the optimal control system in science, engineering and the one branch of applied mathematics operations research. The primary goal of this study is to approximate the numerical solutions for a fractional-order optimal control systems in both free and non-free terminal time (TT). The collocation approach considers a numerical solution to this problem by using a B-cubic spline base. A numerical comparison has been introduced between the analytical soluti

     Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It may be due to impaired insulin secretion, resistance to insulin's peripheral actions, or both. The aim of this study was to estimate the percentage impact of obesity on the incidence of DM, as well as compare the levels of Apelin-36, glutathione-S-transferase, and insulin resistance (IR) in subjects with and without DM for both sexes. This study included 120 subjects, divided into 60 as a control group and 60 as a patient group of both sexes; all were adults between the ages of 30 and 65. The participants with fasting blood sugar, lipid profile, glycated hemoglobin (HbA1c), apelin-36, body mass index, insulin hor

In this work, the conditions of the occurrence of the local bifurcation (such as saddle-node, trans critical ,and pitchfork) of all steady points of a food chain model. With fear and Growly-Martin functional response have been established. It is observed that there is a trans critical and  pitchfork bifurcations near each of  , where as a saddle-node bifurcation near the positive equilibrium point have been occurred. Finally, numerical simulation was used to illustrate the occurrence of the bifurcation of the proposed model.

Crude oil is known globally as one of the major causes of environmental pollution. This chemical compound exerts exhausting impacts on cultivable lands and water surfaces, leading to profound damage to agriculture and aquatic life. Over the years, several bioremediation approaches have evolved to manage this pollution problem properly. A phylum of microorganisms known as cyanobacteria offers an efficient alternative to established bioremediation methods. We conducted the present study to investigate the effectiveness of cyanobacteria in eliminating residual total petroleum hydrocarbon (TPH). Synechococcus algae treated three concentrations of crude oil (0.6, 1.8, and 3 ppm) over four time periods (on days 3, 6, 9, and 12). The g

In this paper, point estimation method for parameters α and λ of the parameters of the Exponential-Rayleigh distribution have been estimated by the use of a simulation technique by using two Bayesian estimation methods; the first Bayesian method of estimation consists of Lindely approximation estimation method and the second Bayesian estimation method consists Tierney and kadane approximation estimation method to estimate all the unknown parameters (α,λ) of Exponential-Rayleigh distribution. Comparisons between these two methods were made by employing mean squares error criterion. Applying a simulation technique with different sample sizes, these methods are being compared.

This paper introduces a new model with two parameters titled “Shanker Weibull distribution". This distribution is obtained by merging the Shanker distribution with a scale of one parameter and the Weibull distribution with a shape parameter. First, we present the mathematical structure of the new distribution, which depends on the survival function for each of the Shanker and Weibull distributions. The statistical functions of this new distribution are presented, such as the cumulative, probability density, hazard and survival functions. In addition, we discuss the behavior of the probability density function and the hazard function by mxamining their shape. We also present the statistical properties of this distribution, which include

One of the generalizations of the usual metric function is b-metric, which allows the researchers a wider aria to derive many results and applications regarding the fixed point theory.  This aim of the article is to advance new three fixed point principles in complete b-metric space  instance  is continuous function in two variables. Here, there are three directions to prove existence and uniqueness of fixed point. First, deriving a result in sense of Branciari’s theorem by combining integral contractive conditions with the idea of cyclic map. Second, applying the notion of cyclic representation regarding maps satisfying general weak conditions including an altering distance function to simulate the cont

In the last decades, functional differential equations have attracted the attention of many researchers; they were interested in the theory and its applications. The most common differential equations of functional type are advanced, neutral, and delay DEs. The theory of oscillatory DEs with retarded arguments has a paramount effect on the qualitative properties of DEs. It is essential to deduce conditions for oscillatory and non-oscillatory solutions. The objective of this paper is to obtain oscillatory conditions for differential equations with retarded arguments. So, the oscillatory behavior has been considered in the nonlinear differential equations (DEs) of neutral type with three delays. Some important conditions of all functions h

We studied in this investigation the changes of the continuous conductivity of the electricity (σ_d.c) due to substituting part of Selenium with Lead in an S₆₀-Se_40-X-Pb_X alloy at weight ratios x = 0, 10, 20, and 30. Our investigation includes an examination of σ_d.c. mechanisms in chalcogenide semiconductors and governing the equations of the continuous D.C. electrical conductivity, and the application of these measured characteristics of S₆₀-Se_40-X-Pb_X glasses to assess Lead's impact on extended, local, and Fermi energy state densities. Some procedures were applied to the materials, such as mixing, grinding, heating in quartz ampoules, placing them