This experiment were conducted to compare the effect of aqueous leaves extract of Melia azedarach and Anastatica hierochuntic with the antibiotic (Enrofloxaccin) for 49 days, 270 chicks one day old (Ross 308) were randomly distributed into 6 treatments with 3 replicates per treatment and 15 chicks per replicate (45 chicks/treatment). The first treatment were the control, antibiotic (enrofloxaccin) were used in the second treatment at rate of 0.5 ml per liter of tap water, in the 3rd and 4th treatment the aqueous leaves extract of Anastatica hierochuntic were used at rate of 10 and 15 mg/L respectively, and in the 5th and 6th treatment the aqueous leaves extract of Melia azedarach were used at rate of 10 and 15 mg / ml resp. At the end of
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The aim of this experiment is to study the effect of antithyroid agent (propylthiouracil) (PTU) on some physiological parameters in domestic chicks. 36 local one 4 week of age day old chicks were used .chicks were distributed randomly in to three groups: (control group) fed on standard diet , while 2nd and 3rd groups were fed diet contain 0.01 and 0.1℅ of antithyroid agent propylthiouracil (PTU) respectively from 1-25 days of age . blood sample were taken from jugular vein at the end of the 4th week in order to study the effect of PTU treatment on blood picture .result revealed that PTU treatment in group treated with 0.1℅ PTU compared with control group significantly increased in red blood cell count ,Heterophils ,basophiles percent
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This study aimed to recognize the different effects of administration of sodium tungstate in developmental indices of the offspring till weaning. Four groups of Albino Wistar pregnant female rats were used, the first one was control while the remaining three groups intubated with Na- tungstate 75, 150 and 300 mg/ kg/ day respectively since the first day of parturition throughout 21 days. Results referred to an elevation in weight gain of rat dams treated with 75 mg/ kg while weight gain of offspring elevated in both doses of 75 and 300 mg/ kg throughout 21 days, teeth and eye orifice were observed in doses of 75 and 300 mg/ kg faster than control while the mean of ovary weight elevated in both 75 and 300 mg/ kg however the dose 300 mg/ k
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Forty five cases, 7-14 day-old chicks were studied, they showed
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In an experimental study to evaluate the immunopathological effect of transfer factor on the
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Thirty-five isolates of Staphylococcus were isolated out of 100 clinical specimens were collected f
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Twenty isolates of Staphylococcus aureus were examined, fourteen from them showed staphylococcin
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The reproductive performance of three imported Holstein herds in Iraq was investigated in a
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Histomorphological study confirmed that the carotid sinus was characterized by an abrupt thinning of elastic tunica media which
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Canine distemper (CD) is an infectious disease that affects dogs and is extremely contagious and lethal, with a high mortality and morbidity rates. It infects a broad variety of animals, including primates, cetaceans, and carnivores causing a multi-systemic pathological condition. This study aimed to detect canine distemper virus (CDV) in blood samples of dogs clinically suspected with distemper at the Baghdad Veterinary Hospital, Baghdad, Iraq. CDV nucleoprotein gene (N) was detected in the whole blood of 46 dogs using reverse transcription-PCR (RT-PCR). The partially amplified (591 bp) fragment of the N gene was detected in 12 of 46 (26%) blood samples of dogs examined. Based on the partial sequencing data of the N gene, three local is
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Colorectal cancer ranks as the third most commonly diagnosed cancer and the second leading cause of cancer-related deaths globally. Fluoroquinolones, particularly Levofloxacin, have garnered interest for their potential anti-cancer effects, primarily due to their high affinity for metallic ions like copper. This affinity enhances their spectrum of activity and enables greater interaction with DNA in cancer cells, thereby inhibiting proliferation. Building on our prior work, where we synthesized copper-modified Levofloxacin (MOLVX), this study explores its therapeutic potential in treating precancerous colorectal lesions, known as Aberrant Crypt Foci (ACF), in a murine model. Sixty female Balb- |
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Omega-7 (palmitoleic acid, 16:1 n7) is a monounsaturated fatty acid that is found to have several beneficial effects. Cisplatin is commonly considered for the treatment of different carcinomas. Cisplatin therapy is restricted due to its nephrotoxicity. Nephrotoxicity caused by cisplatin is thought to be associated with inflammatory reactions among other mechanisms. The aim of the present study was to evaluate the possible anti-inflammatory effect of omega-7 on cisplatin in rats. Thirty adult male Wistar Albino rats were divided randomly into five equal groups, rats of group 1 received liquid paraffin solution orally for 7 consecutive days, rats of group 2 received cisplatin (7.5 mg/kg) by single intraperiton |
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Lead has always been a health risk in developing countries. Lead severely affects liver function. Butyrate is effective in treating inflammatory disorders in animals. Thus, this study aimed to determine whether sodium butyrate mitigates lead acetate-induced hepatotoxicity. In this research, 40 adult female albino rats were randomly assigned to one of four treatment groups for a duration of 35 days as follows: group 1 served as a control, group 2 received sodium butyrate (SB) orally at 200 mg/kg daily, group 3 received lead acetate (LA) orally at 50 mg/kg daily, and group 4 received both SB and LA (SB+LA) orally. Blood was collected for complete blood picture (CBC) and some serum biochemical evaluations. Live |
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The purpose of this research was to investigate the beneficial effects of phosphatidylcholine in reducing changes in both lipid and protein profiles in addition to atherogenic index in adult rats with fructose-induced metabolic syndrome. Thirty-six mature Wistar Albino female rats (Rattus norvegicus) (aged 12-15 weeks and weighing 200±10 g) were divided randomly into four groups (G1, G2, G3, and G4); then variable treatments were orally administered for 62 days as follows: G1 (Control group), received distilled water; G2, treated with phosphatidylcholine (PC) orally (1 g/kg BW); G3 (Fr), orally dosed with 40% fructose and 25% fructose mixed with drinking water; G4 (Fr+PC), were also intuba |
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The goal of this study was to assess the antibacterial efficiency of biogenic silver nanoparticles (AgNPs) and gentamicin against Staphylococcus aureus that can form biofilms. The characterization of AgNPs was confirmed by the scanning electron microscope (SEM) which was spherical and homogenous in form, with a diameter between 25 and 45 nm. The X-ray diffraction (XRD) presented the size of AgNPs to be 50 nm. Energy dispersive spectroscopy (EDS) was used to examine the presence of elemental silver. The three-dimensional structure of silver nanoparticles was discovered using an atomic force microscope (AFM), with a diameter of 47.18 nm on average. The minimum inhibitory concentrations (MIC) and mi |
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Cichlids are among the economically important which serve as a source of food for people around the world. A deep understanding of the population structure and genetic diversity of cichlids are vital for initiation of conservation policies and sustainable aquaculture. There is paucity of information on the patterns of genetic variations among and within cichlids in North-central Nigeria. This study, therefore, investigated population genetic structure of Coptodon zillii, Oreochromis niloticus, and Hemichromis fasciatus collected from different freshwater bodies in North-central Nigeria. Genomic DNA was extracted, and five highly polymorphic RA |
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Dipylidiasis is a zoonotic intestinal cestode disease caused by Dipylidium caninum. The objective of this study was to investigate the prevalence of Dipylidium caninum infections in dogs from Baghdad city. The study involved the impact of sexes, age, during nine months (from January to October 2021) on dipylidiasis infection in pet and stray dogs. 108 faecal samples were collected from (54 pets and 54 stray dogs) then examined for the detection of D. caninum egg capsules and eggs using coprological diagnosis (flotation and sedimentation methods) in the laboratory of parasitology / College of Veterinary Medicine, University of Baghdad |
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Resveratrol (RS) is widely used in medical fields as an antioxidant. Current research investigated the protective role of RS supplement on histomorphometric and histopathological alterations in testes were caused by hydrogen peroxide (H2O2) of rats as an animal model. Thirty-two adult rats were utilized in this study, divided randomly into 4 equal groups as follows. The group C was given tap water only and served as control, the 2nd group (G1) was given 0.5% of H2O2 of tap water, the 3rd group (G2) was given tap water containing 0.5% of H2O2 and intubated RS supplement at 87 mg/kg BW, and 4th group intubated RS supplement 87 |
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This research aimed to evaluate the protective ability of Syzygium aromaticum methanolic extract against Salmonella Typhimurium infection in rabbits. Three groups of eight rabbits were given the following: The first group was subcutaneously given Salmonella
Typhimurium-whole sonicated killed antigen (ST-WSKAg); the second group was orally given S. aromaticum extract as well as KWCSAg-ST subcutaneously; the third group was left as positive control group. The rabbit groups were orally challenged by 9×108 CFU/mL Salmonella Typhimurium then the animals were sacrificed 10 days postchallenge for histopathological study. Intestine, liver, kidney, and spleen were studied for pathological changes. The results showed that the second group ha
Bovine mastitis is a disease that concerns animals' welfare and increases the economic production losses. Bacterial agents such as Staphylococcus species are the main causative agent of bovine mastitis. This bacterial agent expresses some inflammatory cytokines that might enhance the cell-mediated, which may promote the pathogenesis of mastitis. The objective of the current study was to investigate the bovine innate immune response circulating levels of pro-inflammatory and anti-inflammatory cytokines. A total of 10 mL of milk specimens were collected randomly from 100 clinically mastitic cows, and another 20 clinically healthy cows were considered as a control group for the California Mastitis test. The microbiological cultures of milk
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Paracetamol poisoning, whether intentionally or accidentally, is one of the main public health problems since the prevalence of its toxicity increased significantly in many countries. Currently, paracetamol is one of the primary causes of acute liver failure worldwide. The aim of this study was to investigate the potential prophylactic effect of omega-7 fatty acid in protecting male rats' livers from paracetamol-induced liver damage. Thirty albino male rats were divided randomly and equally into five groups and then treated as follows: Group 1 (negative control) rats were orally given liquid paraffin for seven consecutive days. Group 2 (positive control) rats were orally given liquid paraffin for seven conse |
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This study was performed according to FDA protocol to evaluate the developmental effects of carvedilol (P-glycoprotein inhibitor), methotrexate (P-glycoprotein substrate) and their combination at therapeutic doses on pregnant rats. Sixty Albino Wistar rats (40 female rats and 20 males) were allocated randomly into four groups orally administered 0.72 mg/kg carvedilol (Cv-treated group [TG]), 0.36 mg/kg methotrexate (MTX-TG), combined doses carvedilol+methotrexate (Cv+MTX-TG), and distilled water (control group) for 2 months in male and 2 weeks in female rats before mating and after copulation, then approval of pregnancy; dosing continued in female groups during pregnancy and lactation periods. Ha |
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This study was conducted to assess the potential dietary effect of grind seeds of Rhus coriaria (gsRC) with and without exogenous fibrolytic enzymes (EFE) on some lipid profiles and ruminal fermentation characteristics of Awassi male lambs. A total of twenty-four Awassi male lambs weighing 21.56±0.77 kg at 3-4 months of age were randomly divided based on BW into four groups with six animals each. Dietary treatments were provided to lambs for 4 months as follows: control group, fed on a concentrate diet at the rate of 2.5% BW with alfalfa hay daily; gsRC-15 group, fed the control group diet supplemented with 15 g/head dried grind seeds of Rhus coriaria daily with die |
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This study aimed to investigate the potential protective role of Bifidobacterium (B.) infantis in alleviating induced duodenal and colon inflammation associated with ulcerative colitis (UC). Female albino Wister rats (n=24) were randomized into four experimental groups: Control Negative, acetic acid-induced colitis (AA colitis), B. infantis-treated (Bifido), orally gavaged with 1 mL of reference strain B. infantis at 108 CFU/mL for four weeks prior to the induction of colitis, and Bifido+AA colitis. Colitis was induced via intrarectal administration of 4% AA solution. Seven days post-colitis induction, blood samples were |
Knowledge of basic structures is prerequisite for acquiring an in-depth idea about the physiology and immunology of the lymphoid system. The study evaluates the age related histomorphometry of cecal tonsil of Sonali chicken at different postnatal stages in Bangladesh as literatures regarding this are very scarce. The investigation was carried out on 25 healthy Sonali chickens representing different stage of postnatal life: days 1, 14, 28, 42, and 56 (n=5). After ethically sacrifice (cervical subluxation method), cecal tonsil was collected and subjected for both gross and histological studies. Haematoxylin and Eosin stain was done for microscopic study. Morphologically, cecal tonsils were located bilaterally at the junction of small and l
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Lactiplantibacillus plantarum, one of lactic acid bacteria (LAB), is found in various foods, including dairy products, meat, and vegetables, and most of these bacteria offer beneficial effects to humans and animals as potential probiotics with broad-spectrum antimicrobial activities. The aim of this study was evaluating the antibacterial efficacy of L. plantarum against some foodborne bacteria isolated from dairy products. This research involved 34 dairy products, including local and imported milk, cheese, and yogurt sold locally in Baghdad province, Iraq, during May 2022. For the isolation of L. plantarum, a s |
In the treatment of COVID-19, the antiviral medication Favipiravir has proven to be quite successful. Its metabolism is mediated by the enzymes aldehyde oxidase (AO) and xanthine oxidase (XO). This research investigated the potential drug-drug interaction between
favipiravir and amlodipine in hypertensive rabbits. Twenty local adult male rabbits (aged between 10 and 12 months and weighing between 2 and 2.5 kg) were induced with hypertension by 20 mg/kg BW of desoxycorticosterone acetate subcutaneously for three
weeks and then divided randomly into two groups of ten. The first group received a single oral dose of 40 mg/kg BW of favipiravir, while the second group received 5 mg/kg of amlodipine orally for 14 consecutive days to
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Physiological status and litter size can indeed have a significant impact on ewes' hematological parameters, which are essential indicators of their health. Therefore, this study examined the hematological profiles of ewes during pregnancy with single and twins in the Awassi ewes. The present study involved 232 ewes in good health and at sexual maturity. Among them, 123 ewes had single pregnancies, while 109 ewes had twin pregnancies. The age range of the ewes included in the study was between 3.5 and 4.5 years. Hematological tests were conducted on the sheep's blood samples promptly following collection. The findings demonst |
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Infectious laryngotracheitis (ILT) is an acute contagious upper respiratory tract infection of chickens and other birds, caused by Gallid herpesvirus1 (GaHV-1), which has economic importance in the poultry industry. There was no scientific data about the incidence of the disease in broiler farms in Sulaymaniyah province/Iraq. Therefore, this study aimed to investigate ILTV infection in broiler farms in that region. Clinically infected birds from 89 broiler flocks that had respiratory distress, coughing, gasping, tracheal rales, nasal ocular discharge, and congested trachea with purulent exudate, hemorrhagic tracheitis with/or without |
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This study aimed to determine the effect of an ethanolic extract of Salvia hispanica (Sh) seeds on osteoporosis induced by methylprednisolone (MP) in female rabbits by assessing the bone mineral density (BMD), serum levels of calcium, phosphorus, vitamin D, and parathyroid hormone, as well as histopathological changes in the femur bone. Fifty female rabbits (Lepus cuniculus) averaging 1800±125 g and 8±1.4 months old were used in this study. They were randomly allocated to five groups of 10 rabbits each. The negative control group received only subcutaneous normal saline (1 mL/kg BW). The positive control group received MP subcutaneously at a dose |