Background: The daily cleaning routine of the silicone maxillofacial prostheses by the patient may cause some alteration in the materials properties. The purpose of the present study was to investigate the effect of different disinfection procedures on some properties of silicon dioxide reinforced Cosmesil M511 HTV maxillofacial silicone. Materials and Methods: One hundred and sixty (160) specimens were prepared by mixing 5% SiO2 nano particles and 0.5% intrinsic cream color into the silicone polymer according to manufacturer's instructions. Specimens were divided into 4 groups according to the performed test (tear strength, surface hardness, surface roughness and color) with 40 specimens each. Each group was further subdivided according to

The primary objective of root canal therapy is adequate biomechanical preparation of root canal system followed by 3D obturation.in clinics we are encountered with several anatomical variations, which we need to manage efficiently. One of the major factors responsible for failure of root canal therapy is missed canals. Recent technological advances have given the clinician opportunity to identify anatomical variations and treat them to satisfaction.

Background: Breast cancer is the commonest type of malignancy worldwide and in Iraq. It is a serious disease that affects the general health and cause systemic changes that affect the physical and chemical properties of saliva leading to adverse effects on oral health. This study was conducted toassess the tumor marker CA15-3 and selected elements in saliva and their relation to oral health status among breast cancer patients compared to control group. Materials and Methods: The total sample consisted of 60 women aged 35-45 years. 30 women were newly diagnosed with breast cancer before taking any treatment and surgery (study group) and 30 women without clinical signs and symptoms of breast cancer as a control group. Dental caries was record

Background: Numerous epidemiological studies were conducted in Iraq, concerning dental caries and related etiological factors however; most of these studies were concerned with pre-and primary school children and/or those at index ages (12-15years old). At the time studies regarding older ages are very limited. This study was done to determine the prevalence and severity of dental caries and treatment need among high schools girls (16-18 years old) in Al-Mussayb city, Babylon Governorate. Thus, it can be considered as a base line data that allows studying dental caries among permanent dentition, also allows the comparison with other studies in other parts of the world. Material and Method: A total number of 900 high school girls were examin

Background: Alterations in the microhardness and roughness are commonly used to analyze the possible negative effects of bleaching products on restorative materials. This in vitro study evaluated the effect of in-office bleaching (SDI pola office +) on the surface roughness and micro-hardness of four newly developed composite materials (Z350XT –nano-filled, Z250XT-nano-hybrid, Z250-mico-hybrid and Silorane-silorane based). Materials and methods: Eighty circular samples with A3 shading were prepared by using Teflon mold 2mm thickness and 10mm in diameter. 20 samples for each material, 10 samples for base line measurement (surface roughness by using portable profillometer, and micro-hardness by usingDigital Micro Vickers Hardness Test

Background: To evaluate the ISO depth of cure of bulkfill composites and depth of cure which determined by Vickers microhardness test. Materials and Methods: Bulkfill resin composite specimens (n=150) were prepared of three bulkfill composite materials (TetricEvo Ceram, Quixfil and SDR) and light cured by Flash max p3 for 3, 10, 20 seconds and by wood pecker for 10, 20 seconds respectively, a mold was filled with one of the three bulkfill composites and light cured. The specimens removed from the mold and scraped by plastic spatula and the remaining length (absolute length) was measured which represent the ISO depth of cure. After that the specimens were returned into the mold and a microhardness indentation device applied on the specimen

Back ground: Oral lichen planus is a chronic inflammatory disease that affects the mucous membrane of the mouth. Several researchers suggest that oxidative stress is implicated in the pathogenesis of this disorder. It has been hypothesized that melatonin is powerful anti-oxidants and can easily cross the cell membrane and is considered a free radical scavenger of Hydroxid, Oxygen and Nitrogen dioxide, cortisol as a stress hormone and the immunoglobulin A as first line of defense and protection to the mucous membrane of the mouth are interrelated factors for the emergence of oral lichen planus. Aim of this study was to evaluate the level of melatonin, Cortisol and IgA in saliva of patients with oral lichen planus lesions in comparison with p

Background: Nutrition can affect periodontal disease through contributing to microbial growth in the gingival crevice, affecting the immunological response to bacterial antigens and assisting the repair mechanism of the connective tissue at the local site after injury from plaque and calculus. The aim of this study was to assess the prevalence of Oral hygiene (plaque and calculus) and gingivitis in relation to age, gender and nutritional status. Materials and methods: The sample included (444) kindergarten children at age of (4 and 5 years old) males and females from urban areas in Al-Ramadi city. The assessment of nutritional status was performed using anthropometr

Background: Periodontium mainly exposed to injury by trauma or pathologic diseases, Aloe vera is a plant has many basic ingredients in its extracted gel that acts as wound healing accelerator in addition to that it's safe, and economical and without recordable of side effect. This study aimed is to evaluate the effect of topical application of Aloe vera on expression of syndecan -1 by periodontium tissue. Materials and methods: Thirty six male Albino rats were subjected for periodontium defect by electric scaler on the distal sides of both lower anterior teeth. The animals divided into two groups; control group (without treatment) and the experimental group treated with 1µLAloe vera gel/normal saline. Periodontal healing was examined at

Background: Mouth breathing can lead to introduce cold, dry unprepared air that insults the tissue of oral cavity, nasopharynx and lung, leading in turn to pathological changes in oronasal cavity, nasopharyngeal and other respiratory tissue, mouth breathing associated with nasal obstruction may lead to many health problems, in particular oral health problems such as inflammation of gingiva, oral dryness, change in oral environment that may decrease pH, salivary flow rate and increase bacteria and dental caries.Aims of the present study were to assess the oral health condition among mouth breather associated with nasal obstruction, including dental caries, oral cleanliness and gingival health condition as well as to evaluate the changes in s

Background: Masseter muscle is one of the most obvious muscles of mastication and considered as one indicator of jaw muscle activity. It has a major influence on the transverse growth of the midface and the vertical growth of the mandible. This study undertaken to determine the role of cephalometric analysis for discrimination between Cl I and Cl III skeletal relationships, determine the role of ultrasonography in determination of masseter muscle thickness, compare masseter muscle thickness between Cl I and Cl III skeletal relationships, and determine the effect of gender on masseter muscle thickness. Material and Method: The sample of the current study consisted of 70 Iraqi subjects 40 males and 30 females with age ranging 18-25 years. The

Background: The objectives of this study are to evaluate the effect of addition of Multi-Wall Carbon Nano Tubes (MWCNTs) of different concentrations (0.05 mg.mL-1,0.25 mg.mL-1,0.5 mg.mL-1and1 mg.mL-1) on dimethyl sulphoxide DMSO and distilled water (DW) on tooth enamel. It intends to evaluate enamel microhardness in (Kg. m-2) pre and post the application of Multi-Wall Carbon Nano Tubes (MWCNTs). Materials and Methods: Thirty specimens prepared for the present study to measure the hardness of the enamel. Results: The results showed that a significant increase in the enamel microhardness for groups 0.05 mg/mL (group B), 0.25 mg/mL (group C), 0.5 mg/mL (group D) and 1 mg/mL (group E) compared with control group (group A) in dimethyl sulphoxi

Background: One of the most common and prevalent oral diseases among adolescents is periodontal disease particularly gingivitis, however enamel anomalies and dental trauma could occur. Aims of the study: This study was conducted among 14-15 years intermediate school male students in urban area of Al-Khalis city to assess the oral hygiene (dental plaque) and to estimate the prevalence and severity of gingivitis, enamel anomalies, as well as traumatic dental injuries, furthermore to show the significant difference between these two ages concerning these oral problems. Materials and methods: In this study the total sample consisted of 735 students (397 aged 15 years and 338 aged 14 years ). In present study dental plaque was recorded accord

Background: Bone regeneration in dehiscence and fenestration defect can be improved with the use of platelet rich fibrin (PRF) that provides a scaffold for new bone regeneration. This study was conducted to assess the effectiveness of PRF as a graft material and membrane in dehiscence and fenestration defects. Materials and Methods: This prospective clinical study included patients who received dental implants that demonstrated peri-implant defects which were augmented using Leukocyte- PRF (L-PRF) or Advanced-PRF (A-PRF). Twenty four weeks postoperatively the defect resolution and the density of regenerated bone were assessed by CBCT and re-entry surgery. The assessment also included measurement of primary and secondary implant stability

Background: Various fluids in the oral environment can affect the surface roughness of resin composites. This in vitro study was conducted to determine the influence of the mouth rinses on surface roughness of two methacrylate-based resin (nanofilled and packable composite) and siloraine-based resin composites.

Materials and methods: Disc-shaped specimens (12 mm in diameter and 2mm in height) were prepared from three types of composi

Background: Imprelon® Biostar foils are new alternative tray material that has become increasingly popular because oftheir several advantages. Also, (Duran®) is another type of Biostar foils which is used in splint therapy. This study assessed some mechanical properties of these two types Biostar sheets in comparison with some types of acrylic resins used for construction of trays and splints. Materials and Methods: A total of 150 specimens were prepared, 30 specimens for each test, 10 for each group material in order to assess some mechanical properties of the Imprelon® Biostar foil (dimension stability, surface roughness and shear bond strength of Imprelon® materialto zinc oxide impression material) and compare them to that of the oth

ABSTRACT Background: Neuropilin 1(NRP1) is considered a novel non - tyrosine kinase co- receptor for the vascular endothelial growth factors (VEGF). First discovered on migrating neurons. NRP1is suggested to be up-regulated in cells of different types of cancer and implicated with advanced disease. The aim of this study was to investigate the variation in expression of NRP1 in oral, laryngeal and skin squamous cell carcinoma. Materials and methods: Tissue sections from 120 formalin fixed- paraffin embedded blocks histopathologically diagnosed as oral, laryngeal and skin SCC (40 blocks for each),immunohistohemically stained in immunoperoxidase method with monoclonal antibodies to NRP1, the localization of expression was examined and the res

Background: Periodontitis is an inflammatory disease that affects the supporting tissues of the teeth; Smoking is an important risk factor for periodontitis induces alveolar bone loss and cause an imbalance between bone resorption and bone deposition. The purpose of this study is to detect and compare the presence of incipient periodontitis among young smokers and non-smokers by measuring the distance between cement-enamel junction and alveolar crest (CEJ-Ac) using Cone Beam Computed Tomography (CBCT). Material and methods: The total sample composed of fifty two participants, thirty one smokers and twenty one non-smokers (age range 14-22 years). Periodontal parameters: plaque index (PLI), gingival index (GI) were recorded for all teeth exc

Green tea is regarded as a healthy beverage due to the biological action of polyphenols, specifically catechins. Researchers investigated the inhibitory effects of green tea (Camellia sinensis) plant on both Gram- positive and Gram-negative bacteria. Periodontitis is mainly initiated when dysbiosis of the subgingival microbiome takes place. Porphyromonas gingivalis is one of the key pathogens involved in the initiation and progression of periodontitis when its levels in subgingival biofilm overwhelm the host's immune system. It is the main pathogen that is significantly linked to severe periodontal disease. In this study, details about P. gingivalis including information about its structure, virulence factors were provi

The purpose of endodontic treatment is to eliminate all germs, microbial by-products, and vital tissues from the root canal system. Root canals can be mechanically and chemically used for this purpose. The needs and details of the irrigation solutions are described in this article. Because of its wide range of antibacterial activities and its ability to dissolve organic tissues, sodium hypochlorite is suggested as the main irrigation. On the contrary, chelation solutions are recommended as supplemental treatments to either eliminate the smear layer or prevent it from forming on the dentin surface. Data: Only articles that were published electronically were searched within the review. Sources: ‘Google Scholar’ and "Pub-med" websites w

Background: periodontitis is a multifactorial oral inflammatory disease characterized by the gradual loss of bone and eventual tooth loss. It starts with microbes and is then influenced by the environment. A diverse family of host defense major compounds known as antimicrobial peptides react quickly to combat microbial invasion and challenge. These little cationic peptides are crucial for the development of innate immunity. The goal of this study was to evaluate the blood levels of healthy individuals and patients with periodontitis for cathelicidins and human beta-defensin-1. In this case-control study, 35 healthy volunteers (matched exactly by age and sex to the patients) and 50 periodontitis patients (aged 20 to 59) participated. In t

Background: Demineralization and white spot lesions are the most common complications in fixed orthodontic treatment. It is useful to enhance the remineralization properties of the orthodontic primer by the addition of remineralizing agents. Fluoride and calcium are regarded as the main component of enamel fluorohydroxyapatite crystals. This pilot study compared three mixing methods of calcium fluoride nanoparticles (nCaF₂) with conventional orthodontic primer (Transbond XT^TM) to develop a primer with enamel remineralization properties. Materials and methods: The nanoparticles were added to Transbond XT^TM primer to form 20% (w/w) of the final solution. Three dark plastic bottles were prepared and stored u

Background: Recurrent aphthous stomatitis remains the most common ulcerative disease of the oral mucosa that exists as painfull round shallow ulcers with a well-defined erythematous margin and a yellowish grey pseudomembranous centre. Salivary irisin is an identified adipomyokine and research has revealed that it has an anti-inflammatory effect and is a novel myokine; it is synthesized in skeletal muscle and adipose tissue. The aim of the present study was to evaluate the relation of salivary irisin to recurrent aphthous ulcers and weight status in Diyala City / Iraq. Materials and methods: A cross-sectional comparative st

Background: The ultimate purpose of this prospective study is to estimate and measure swelling associated with surgical extrac¬tion of impacted mandibular third molars in different four post-operative times and to identify the risk factors associated with determination of their risk degree. Material and Methods: In this prospective cohort study 159 consecutive cases in which removal of impacted lower third molars in 107outpatients were evaluated. Five groups of variables have been studied which are regarded as a potential factor for swelling after mandibular third removal which will enable the surgeon to predict and counsel high risk patients in order to offer a preventive strategy. Results: Facial measurements were carried out on 1st, 2

Background: Silicone elastomers have been extensively used as the most acceptable material in the manufacturing of maxillofacial and other kinds of prosthetic devices. The durability of maxillofacial prostheses depends on the material chosen, the patient's attitude and feelings regarding the prosthesis, and how they perform for specific needs. Aims: This study aimed to investigate the influence of adding barium titanate (BaTiO3) nanoparticles on the mechanical and physical characteristics of room-temperature-vulcanized (RTV) VerSilTal (VST-50) maxillofacial silicone elastomer, including thermal conductivity, tear strength, and water absorption and solubility. Materials and methods: 0.5 wt% and 0.75 wt% BaTiO3 nanoparticles were added to

Background: Early detection of periodontal tissue loss prevents further development and halts additional damage.  The purpose of this study was to investigate the diagnostic ability of salivary Pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen (ICTP) and deoxypyridinoline (DPD) in differentiating periodontitis from periodontal health. Material and method: A case-control included 80 participants who were divided into two groups: 40 periodontitis patients and 40 subjects with a healthy periodontium. Salivary samples were collected from each patient, followed by a clinical examination. The collected saliva samples were centrifuged and frozen at -80⁰C until analysis using Enzyme-Linked Immunosorbent Assay. Results:

Background: Aggressive global pandemics such as COVID-19 can disrupt societies tragically, imposing a suspension to almost every field throughout the world; the orthodontic treatment and follow-up is no exemption. Objectives: To provide practical recommendations about resuming treatment for orthodontic patients during the “Return-to-Practice” phase and emphasize the validity of certain digital interceptive measures post global pandemics to minify the risk of infection spread. Materials and Methods: Sources of information pertaining to orthodontic/therapeutic implications during the COVID-19 pandemic were searched using electronic databases including COVID-19 Open Research Dataset (CORD-19 2020), Google Scholar, Scopus, PubMed, MEDLIN

background: This study aimed to evaluate the effect of bioactive composite (ACTIVA) on enamel demineralisation when used as an orthodontic adhesive, compared to other adhesives. Materials and methods: Human upper premolars (n=64) were randomly divided into two equal groups; the first group stored the bonded teeth in deionised water for 30 days at 37°C, and the second group exposed the bonded teeth to acidic media. Each group was further subdivided into four subgroups, with eight premolars in each subgroup, based on the type of adhesive used to bond metal brackets: non-fluoride-releasing adhesive (Transbond XT), fluoride-releasing adhesive (Light Bond), light-cured, resin-reinforced glass ionomer (GC Fuji ortho LC), and bioactive restora

Background: Titanium alloy (Ti6Al4V) is considered a promising material for prosthetic dental applications due to its superior density, high strength, improved corrosion resistance and superior biocompatibility. Due to the low strength and brittleness of the practicable denture foundation material in heat-cured acrylic resin, improving the strength properties is a crucial issue. The present study aimed to evaluate the influence of Ti6Al4V alloy particles on the tensile strength transverse strength, and the surface hardness of heat-cured PMMA as a base material. Materials and methods: A total of 75 specimens were prepared by combining heat-cured acrylic resin with Ti6Al4V additive particles (0.5, 1, 1.5, and 2 wt. % respectively). Each gr

Background: The interactions of genetic and environmental factors may account for the variability in the expression of malocclusion. The study of malocclusion etiology is fundamental to understand the biology underlying craniofacial growth and dental relations. Understanding biology will improve progress toward effective treatment and prevention, thereby decreasing the burden of this condition. Aims: The present study was set out to investigate the association of the single nucleotide polymorphisms (SNPs) in different genes (rs2249492 in COLA1A, rs4434184 in SOX2, rs2162540 in FGFR2, rs11696257 in MAFB, and rs881301 in FGFR1) with Class III malocclusion. Materials and Methods: A total of 10 patients, comprising 5 with Skeletal Class I an