Background: Growing evidence has indicated that women with type 2 diabetes mellitus are at an increased risk of developing breast cancer. However, as a major adjuvant treatment, the influence of hormone therapy such as exogenous insulin on type 2 diabetes mellitus in primary breast-cancer remains controversial. 

Objective: To explore the relationship between different types of hypoglycemic medications for diabetes and the factors that may contribute to the initiation of breast cancer.

Methods: The study included 80 blood samples taken from 80 females recruited from Ibn Al-Bitar Center for Cardiac Surgery Hospital in Baghdad, Iraq, between November 2022 and February 2023. T

Background: The adhesion of bacteria to biotic and abiotic surfaces reflects their ability to cause infectious diseases. The distinction between the ability of Pseudomonas aeruginosa bacteria to adhere to biotic and abiotic surfaces is not clear in the literature.

Objectives: The current study aims to shed light on the extent of similarities and differences between P. aeruginosa in terms of their ability to adhere to different biotic and abiotic surfaces.

Materials and Methods: ten isolates of P. aeruginosa were isolated from 100 wound and burn swabs. The isolates were identified using biochemical and phenotypic t

Background: Omentin-1 is mainly expressed in stromal vascular cells of adipose tissue and can also be expressed in airway goblet cells, mesothelial cells, and vascular cells. Fibroblast growth factor 23 (FGF-23), generated by bone cells, regulates phosphate and vitamin D metabolism by regulating phosphate reabsorption in the kidneys and inhibiting vitamin D activation. Vitamin D is a fat-soluble vitamin that regulates calcium absorption, bone health, and immunological function. Prostate cancer is a significant health concern for men worldwide. Several studies demonstrated a link between these variables and cancer as they exert important anti-inflammatory, antioxidative, and anti-cancer functions.  

Object

الخلفية: الحركيات الخلوية لها مساهمة أساسية في الاستجابة الالتهابية وتطور الالتهاب المزمن. لذلك لها دور محوري في التسبب في التهاب المفاصل الرثوي. ترتبط البين ابيضاضي ارتباطًا بالتهاب المفاصل الرثوي ، والدور الدقيق لبعض البين ابيضاضيات في التسبب في التهاب المفاصل الرثوي غير معروف حتى الآن.
الهدف: لتقييم مستويات البين ابيضاضيات ونسبتها ، حيث أن مستويات البين ابيضاضي 35 و 39 في مرضى التهاب المفاصل الرثوي لم ي

الخلفية: النتيجة الأكثر شيوعًا لمرض السكري هي اعتلال الشبكية السكري. يلعب الإجهاد التأكسدي جزءًا مهمًا من مسببات مرض السكري واعتلال الشبكية السكري. مالونديالديهيد هو ديالديهيد ذو سمية معتدلة وكثيرا ما يستخدم كمؤشر حيوي للإجهاد التأكسدي وبيروكسيد الدهون.

الأهداف: كان الهدف من هذه الدراسة هو تقييم مستويات مصل الدم للمالونديالديهايد في المرضى الذين يعانون من اعتلال الشبكيةالسكري والذ

نبذة مختصرة

الارضية: انصباب الجنب الدموي الناتج عن الشدة الخارجية (بيلة دموية الصادمة) هي تجمع الدم داخل التجويف الجنبي بسبب اختراق أو إصابة حادة تؤدي إلى تراكم الدم داخل التجويف الجنبي مع عواقبه التنفسية والديناميكية الدموية.

الهدف: هو دراسة بأثر رجعي من ثمانين مريضا يعانون من بيلة دموية الصادمة الراقدين في مستشفى ابن النفيس التعليمي خلال (1 أغسطس 2018 إلى 30 سبت

Background: The radiological scoring of severity and progression of lung abnormalities is of great value for clinicians to define the clinical management of COVID-19 patients.

Objectives: The purpose of this study is to implement the Brixia scoring tool to assess the pattern of lung involvement in patients with COVID-19 to help predict the severity of their clinical outcome, where the clinical outcome correlates to outpatient, inpatient and/or ICU admission.

Patients and Methods: We conducted a case series study at the Sheikh Khalifa Medical City Ajman (SKMCA), United Arab Emirates from 14 March to 30 October 2020. Patients’ medical records were reviewed and followed up f

Background: Colorectal cancer (CRC) is the third most prevalent cancer worldwide with 1.80 million new
cases and 862,000 deaths in 2018. Depending on the stage, upfront surgery is the main form of treatment,
followed by adjuvant chemotherapy. Many drugs were approved by the U.S. Food and Drug Administration
for the treatment of CRC, one of which is Capecitabine. During cancer treatment, patient-reported symptoms
and quality of life parameters can provide additional information to evaluate and compare the efficacy and
toxicity of the treatments. Despite the importance of this issue, there is no published data that evaluates this
vital parameter in Iraqi patients receiving anti-cancer drugs, in general,

خلفية البحث:  أظهر انتشار البكتيريا المقاومة للأدوية المتعددة ومساهمتها في زيادة معدلات الاعتلال والوفيات بسبب الأمراض التي يصعب علاجها والتي تسببها هذه البكتيريا ، الحاجة إلى تطوير واستخدام عوامل بديلة مضادة للميكروبات للسيطرة على البكتيريا المقاومة للأدوية المتعددة. كان هناك اهتمام متزايد بالنباتات الطبية والأعشاب ومستخلصاتها لاكتشاف بدائل علاجية طبيعية جديدة. لذلك هدفت هذه الدراسة الحالية

Background: Nicotine addiction is the inevitable result for many smokers. Regardless of control and intervention strategies for smoking cessation, it is important to determine the nicotine dependence score for each smoker. 

Objectives: To assess the nicotine dependence by FAGERSTRŐM Test for nicotine dependence (FTND score) and to find out the association of nicotine dependence with some smoking-related comorbidities and with the level of education.

Patients and Methods: This is a cross-sectional study on a total of 200 adult smokers who were attending different departments in Al-Imamain Al-Kadhimain Medical City during the period from April 2019 to October 2019. Demograp

Background: On March 2020, the first case of coronavirus disease-19 was registered in the Kingdom of Saudi Arabia and subsequently the first mortality case. The predicting factors for patients' outcomes are essential to triage patients with COVID-19. This may provide low-cost facilities that help in the fight against the existing global pandemic.   

Objectives: This study aimed to predict hospitalization and death outcomes of COVID-19 patients using the simplest facilities.

Method: The electronic medical records of 280 COVID-19 patients between March 2020 and May 2021 were retrieved from a multi-centre of healthcare facilities across Kingdom of Saudi Arabian cites. All de

البكتريا الحلزونية البوابية هي أحد الكائنات الحية المعدية المعوية التي تصيب أكثر من نصف سكان العالم. كان الهدف من هذه الدراسة هو عزل والتعرف على بكتيريا الحلزونية البوابية من عينات المريض (الخزعات) باستخدام إجراءات مختلفة ، والاختبارات البيوكيميائية ، وحساسية البكتيريا للمضادات الحيوية. 90 مريضاً يعانون من أعراض عسر الهضم يمثلون فئات عمرية مختلفة من كلا الجنسين. خضعوا لتنظير الجهاز الهضمي "العلوي" التشخيصي

Background: - Carcinoma of the lung has became the most common type of cancer since 1985 & the most common cause of cancer death in both males & females.
Aim of study: - To assess the diagnostic accuracy of bronchial wash cytology & application of immunocytochemical methods, using two tumor markers (low molecular weight cytokeratin & epithelial membrane antigen) for more accurate & precise diagnosis of lung tumors.
Patients, materials and methods: - Fifty fifes suspected lung cancer cases according to their clinicoradiological examinations were included in this study.
Bronchial wash cytology was performed for all the 55 patients. Smears were stained by conventional cytological stain i

Background:
Acute leukemias are clonal neoplastic proliferations of immature cells of the hemopoietic system. They are divided into acute myeloid leukemia (AML), acute
lymphoblastic leukemia (ALL) and acute undifferentiated leukemia (AUL). LDH has been suggested as a possible non-specific tumor marker for many years, and total serum LDH is
frequently elevated in neoplastic diseases. The aims of the study are to evaluate the significance of increased serum LDH levels in patients with acute leukemia and to
determine the importance of serum LDH level in the follow up and assessment of treatment responses.
Patients, Materials and Methods:
This study was conducted at Baghdad Teaching Hospital in Medical C

Background:
Inflammation has been shown to play a role in atherosclerosis and acute coronary syndromes. An elevated total WBC count has been associated with increased cardiovascular
risk, but which leukocyte subtypes carry this risk. is uncertain. This study was designed to determine the effect of WBC count and other inflammatory markers on severity and
outcome of patients with UA/NSTEMI.
Patients and Methods:
Seventy (70) patients with UA / NSTEMI admitted to CCU at the Iraqi Center for Heart Diseases were subjected to thorough history and physical examination and WBC indices to
find their relation to clinical severity and outcome for both in-hospital and/month after discharge. The results were comp

Background:
Angiogenesis plays a crucial role in tumorigensis; several reports have described a significant increase in microvessel density (MVD) in colorectal carcinogenesis There are
several methods to measure the angiogenesis in neoplasms, but immunohitochemistry seems to be the mainstay of all. This method enable us to measure the tumor microvessel densities highlighted by using antibodies directed against endothelial cell markers like CD31,CD34 or others; then assessment of MVD by manual count of the number of microvessels in what appears to be the most vascular area of the tumor(called the hot spot) using a protocol described by Weidner et al.Automated cellular imaging system is used to analyze

Background: TIDM is known to be polygenic disease that appears from the interaction of mutation in multiple genes including HLA. The autoimmune mediated destruction of
pancreatic β-cells is reflected by the presence of autoantibodies against prominent antigens in the pancreatic β-cells.
Objective: This study was designed to investigate the role of HLA-class I and class II antigens in the etiology of type 1 diabetes mellitus (T1DM) and also assessment of
glutamic acid decarboxylase (GAD65) autoantibodies in the patients at the onset of the disease.
Patients & Methods: Sixty T1DM patients who were newly onset of the disease (diagnosed less than five months) were selected. Eighty apparently healthy

Objective:
To assess the subjective rating of quality of life of college students in University Of Science And Technology in Jordan as a sample of healthy educated
young population through applying the WHOQOL-BREF instrument as a field trial in Jordan and to compare the finding with similar previous study.
Methods
Three hundreds forms of Arabic version of the self-reporting questionnaire WHOQOL-BREF were distributed to students of third class attending the lecture
halls in three colleges (college of Engineering, college of science, college of  medicine) in the university campus in AL Ramtha–Jordan from the first of March
to first of may 2007., with respect to university regulations,interested parti

Introduction:
Neonatal Respiratory distress syndrome (RDS) remains one of the major cause's neonatal morbidity and mortality despite advances in perinatal care especially in developed
countries.
Objectives:
The aims of this study were to find out me risk factors of mothers and newborns (NB) which increase the incidence, morbidity, and mortality of RDS.
Patients & Methods:
A prospective descriptive cross-sectional study was conducted on 100 live NR infants born at neonatal care units in Baghdad hospital & private nursing home (medical city
complex) / Baghdad in the period from the first of March to the end of June 2006. They were presented with RDS, which was diagnosed clinically and radio-

Background: streptococcal pneumonia is one of the most common pathogens that cause otolaryngological disease.

Background : From the standpoint of mortality &morbidity, cancer is by far the most important clinical problem that concerns the breast today .The age adjusted incidence of new cases has been increasing steadily with increase in the incidence among the Iraqi women during the last few years .
Materials &method : A prospective study was arranged to assess the occurrence of postsurgical loco-regional recurrence of breast carcinoma in the Iraqi female patients , a total
number of 91 female patients were assessed during period from Dec.2000 to Dec.2002, the 
median period of follow up was two years.
Result : Loco-regional recurrence developed in 20 patients (22%). Chest wall and axilla were th

Background:To evaluate the accuracy of serum uric acid to predict maternal and fetal complications in women with pre- eclampsia.
Design: Prospective study. Setting: Tikrit Teaching Hospital.
Subject and Methods: Fifty normotensive and forty-three pre-eclamptic pregnant women at (20-24) weeks of gestation were the study subject, serum concentrations of uric acid
were measured and examine the correlations between serum uric acid level with fetal and maternal complications.
Result: Serum concentration of uric acid in pre-eclamptic women were significantly higher than in gestational age match normotensive pregnant women, and women with pre-eclampsia
and elevated uric acid concentration at increased risk of

Background: Acute inflammatory demylinating polyneuropathy (Guillain-Barr'e syndrome) is the commonest cause of acute neuromuscular paralysis in most countries. The onset of symptoms in patients with GBS can either be acute or sub acute .Ventilatory failure is primarily caused by inspiratory muscles weakness although weakness of abdominal and accessory muscles of respiration, retained airway secretion leading to aspiration and atelectasis are all contributing factors. Nutritional support of critically sick children is important for metabolic maintenance and
tissue repair.
Methods: To identify clinical and respiratory features associated with progression to respiratory failure in children with GBS. Twen

Background: Human leukocyte antigen (HLA) is the most polymorphic genetic system in man. The genes of this region influence susceptibility to certain disease.
Objectives: This study was established to shed light on the possible association of HLA class I and II antigens with RV patients.
Patients and Methods: Lymphocytotoxicity assay for HLA for class I and II typing had been done for (100) Iraqi patients suffering from rheumatic valvulitis (RV), the control groups consisting of (75 healthy individuals and 35 non rheumatic heart disease (NRHD) patients ).
Results: The results showed a significant association of A33-Ags with these patients as compared with healthy and cardiac controls (P=0.005), (P=0.033)

Background: Reports denote that changes in day length enhance or suppress components of immune function in several mammalian species. The aim of present experimental study is
directed to test the hypothesis deals with the effect of photoperiods on some immune limbs responsiveness.
Materials and Methods: Twenty six male and female BALB/C mice, 5-7 weeks old, 14- 18gm weight divided into two groups, test groups (n.=8 mice for each sex) and control
groups (n.=5 for each sex). Test groups were kept in a dark room for a month, while control groups were kept in a room where the photoperiod was day light: darkness 12:12hr. All
studied groups immunized with o.2ml (10% sheep red blood cells) on day 4 and 8 of the l

Background: Chronic obstructive pulmonary disease (COPD) is a common disease and it accounts for over 10% of all hospital medical admission. Cigarette smoking is the most important risk factor. Pulmonary arterial hypertension (PHT) is a common complication of COPD and the increase in pulmonary artery pressure is often mild to moderate. The presence of pulmonary arterial pressure and its severity is readily and reliably determined by transthoracic echocardiography in majority of COPD patients.
Patients and Methods: This study included 55 patients with mean age 65.6 ±8.2 years .The mean duration of symptoms was 18 ±10 months. 32 patients (58%) were current smoker, 18 patients (33%) were exsmoker and 5 pat

Background: There were definite changes in pathologies involving thyroid gland allover the world with increasing incidence of thyrotoxicosis and differentiated malignancies.
Patients and methods: 224 patients were operated upon by the same surgeon during 15 years period. Those patients were divided into two groups (GI from June 1990 up to June 2000) and (GII from June 2000-June 2005).
Results: female to male ratio was 3.3:1. The most common presentation among both groups was Multinodular goiter (MNG) 76.8%. toxic goiter was recorded in 24% of patient with increase among GII patients. A significant effect of stress on the increasing incidence of thyrotoxicosis was elicited in more than 50% of patients w

Propolis is a complex resinous bee product that has a wide range of biological activities. In the present investigation, two oral doses (10 and 20 mg/kg/day) of propolis (ethanol extract) were evaluated immunologically in albino male mice (80 animals) through three types of experiments. In the first, the propolis was tested alone, while in the second and third experiments, propolis was given before and after the immune suppressive drug MMC (pre- and post treatments, respectively). The three experiments were paralleled with three negative controls, in which the propolis was replaced with distilled water. In the first experiment, the dose 10 mg/kg of propolis enhanced the parameters investigated, and a si

Bagkground:Chlorpromazine is widely used in human medicine in the therapy of schizophrenia, organic psychosis and the manic phase of manic depressive illness. It expressed a selective cytotoxicity and the results of genotoxicity were positive.
Objectives: This study is designed to explore the effect of chlorpromazine on irradiated and non irradiated calf thymus double strands DNA (ctdsDNA) molecule.
Methods: Aliquots of irradiated (subjected to UVB light) and non-radiated ctdsDNA samples were incubatyed with different concentrations of chlorpromazine. Further series of experiments studied the simultaneous effects of chlorpromazine and UVB light on aliquots of ctdsDNA, The changes in optic densities of

Background : It had been indentified by histological, histochemical and morphometrical studies that peganum harmala is a mammogenic herb and borage officinalis is a lactogenic one . To complete our investigation about these two herbs , we performed electron microscopical study.
Materials and methods : Rats were grouped according to their physiological status into three groups . Each group was subdivided in to three subgroups : one control and two experimental . The two experimental group were treated daily; the 1st one with an aqueous extract of peganum harmala seeds and the 2nd with an aqueous extract of borage officinalis flowers . After two weeks of treatment , mammary glands were employed for electron