Background: Human Cytomegalovirus (HCMV) infects a wide range of human cells, including colonic epithelial cells that give rise to adenomas and adenocarcinomas. Persistent productive infection of tumor cells is essential for oncomodulation by HCMV.This study aimed to detect HCMV matrix protein using in situ hybridization technique (ISH) in colorectal adenocarcinoma compared to normal colon tissues, and to the presence of cytomegalovirus inclusion bodies in infected colorectal carcinomas.
Patients and methods: Twenty six of colorectal adenocarcinomas were obtained in paraffin-blocks compared to 10 normal colon specimens which were age and sex matched as control group. Detection of HCMV was obtained by in s
Background: Several biological factors such as bacterial infections and immunological status are implicated in predisposing individuals to bladder cancer. Bacterial infection of urinary tract has been related to increase the risk of bladder cancer.
Patients and Methods: Resected tumors of a total of 73 patients were obtained under sterile surgical conditions. Biopsy processing samples and culture procedures of biopsy samples were mentioned in the text.
Results: Bacterial growth was observed in 48 biopsy tissues of those patients represent (65.8%) while, 25(34.2%) yielded no growth (negative results). It is obvious that E. coli is the most predominant organisms followed by K. pneumoniae and Ps. Aer
Background: Acute renal failure is characterized by impaired excretory endocrine homeostatic and metabolic functions of the kidneys.
Objective: The aim of this study is to look for the role of sex hormones, waist circumference and leptinemia in patients with acute renal failure.
Subjects and Methods: 55 subjects were involved in this study, 30 had acute renal failure and the remaining 25 subjects were normal healthy individuals who served as
a control. The age range of the patients was between 25 and 45 years with a mean of 37±8.2 years. Five mls of blood were withdrawn from each subject by vein puncture. Enzyme
linked immuno assay (ELISA) was used for the measurement of serum leptin level. Radi
Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity.
Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients.
Methods: Latex agglutination test(AG) & single radial immunoassay(SRIA) were used to asses CRP, IgMJgGJgA,, C, in 74 patients with RA.
Results: IgA & IgG were significantly increased, while the mean ofC3, C4 were slightly elevated in RA patients .
Conclusion: There is correlation between IgG and IgM with joint deformity and joint swelling respectively, while C3 was showed statistically significant P<0.01 with joint
stiffness, joint swelling and Rheumatoid nodule, whe
Background: Decreased thyroid hormone synthesis and low levels of circulating thyroid hormones result in clinical and biochemical changes in hypothyroidism. As
deficiency of thyroid hormones causes many metabolic processes to slow down, therefore; the maintenance of optimal health requires an adequate supply of
carbohydrates, proteins and lipids, and macronutrients, micronutrients, and trace elements.
Objective: Study the effect of the changing in serum level of the trace elements; Zn, Cu, Mn, and Se in hypothyroid patient.
Patients and Method: Thirty seven hypothyroid patients and fifteen normal healthy control persons were participated in this study. Serum zinc and copper were determined using
Backgrounds: Tribulus terrestris is one of the traditional herbs that have a revolutionary breakthrough in the management of erectile dysfunction and
have become world –wide as an “instant treatment”
Materials & Methods: Tribulus terrestris was given daily to mature male mouse in a dose of 2 mg /kg body weight for 14 days .10% formalin fixed
paraffin sections were performed for histological, histochemical and morphometrical studies.
Results: Histological and histochemical studies demonstrated a considerable increase in the number of spermatocytes, spermatids and sperms in parallel
with an increase number of interstitial (Leydig) cells. Morphometrically, the thickness of seminiferous tubul
Background:
الخلفية : يعتبر تقلص الشرايين احد اهم انواع امراض الشرايين التاجية و نسبة حدوثه تتراوح من 1 – 5 % خلال قسطرة الشرايين التاجية . تقلص الشرايين التاجية الذي يحدث تلقائيا يودي الى متلازمة برنزميتال.
تهدف هذه الدراسة الى تقييم نسبة حدوث تقلص الشرايين التاجية للمرضى المجراة لهم عملية قسطرة الشرايين التاجية (التشخصية و العلاجية) و معرفة الخصائص السريرية و ا
... Show Moreالمقدمة: -الام البطن الحاده تقليديا تشير الى الإم البطن التي لم يمر على حدوثها اكثر من سبعه أيام، دور المفراس في تقيم هذه الحالات اصبح ذو اهميه متزايدة بسبب الدقة العالية في تشخيص يعض حالات البطن الحاده مثل التهاب الزائدة الدودية والتهاب نتوءات القولون بخصوص المفراس متعدد الكواشف او متعدد الابعاد (البعد الثلاثي). لقد تبين ان استخدام الملونات الوردية تزيد من دقه تشخيص المفراس. اعلما انه
... Show Moreالخلفية: تهدف هذه الدراسة الى تقييم المضاعفات الوعائية التي تحدث بعد القسطرة التشخيصية و التداخل القسطاري من خلال الشريان الفخدي , لانه لوحظ ان المضاعفات الوعائية عامل مهم في المراضه بعد القسطرة التشخيصية و التداخل القسطاري
طريقة البحث: تم اجراء هذه الدراسة في مركزين تخصصين لامراض القلب هما المركز العراقي لامراض القلب و مستشفى ابن البيطار لجراحة القلب ام
... Show Moreخلفية البحث:تعتبر دوالي الخصية من الامراض الشائعة والتي تؤثر على القدره الانجابية عند الرجال و تقسم حالات دوالي الخصية حسب قطر الاوردة الى الحالات السريرية و التي تكتشف خلال الفحص السريري و الحالات غير السريرية و التي تكتشف فقط خلال فحص الموجات فوق الصوتية (السونار). ان تأثير دوالي الخصية السريري و الذي تكون به الاوردة كبيرة معلوم على السائل المنوي و وضائف الحيامن و لكن معالجة حالات
... Show MoreBackground: the integrity of cardiovascular reflexes & autonomic activities can be assessed by different tests and different techniques. However most of these studies carried out on male subject & usually on young group only .very little researches available concerning the differences in cardiovascular reflexes between male & female in different age group.
Aim of study: is to investigate the differences in cardiovascular reflexes in young , old male & female in response to go head up tilting using totally non- invasive system .
Sub. & Methods: this study was carried out in AL-Najaf teaching hospital on 85 normal sub. , 41 males c6 44 females they were divided into two age groups (20-40 years) & (41-60 years)
خلفية : تعد عقيدات الغدة الدرقية من المشاكل الصحية الشائعة تبرز أهميتها بإستبعاد الاورام السرطانية من هذه العقد والتي تحصل بنسبة 7% - 15% من الحالات ومن الجدير بالذكر أنه ونتيجة لعوامل متعددة أصبح المعدل السنوي للإصابة بسرطان الغدة الدرقية ثلاثة أضعاف ماكان عليه في السابق . إن سرطان الغدة الدرقية العرضي هو أي سرطان تابع للغدة الدرقية والذي لم يستدل عليه عن طريق التحقيقات والفحوصات السابقة للعمليات الجراح
... Show MoreObjectives: (I) to describe the hemodynamic and electrocardiograph (ECG) responses in patients with acute myocardial infraction (AMI) to a low level treadmill test (2) to assess the safety of low-level treadmill testing after AMI (3) to determine if information gained from the test can be used for discharge planning.
Methods: 50 consecutive patients with AMI were subjected for symptoms limited treadmill testing in the CCU of University Teaching Hospital Iraqi medical College, their age range was from 30-70 with mean age of 55 years. Blood pressure, heart rate, and ECG during a low level treadmill test studied 6 days after AML They were divided into two groups, group I those who could finish the test and group 2 those who couldn't fini
Objective To detect the changes in serum Lipids among Iraqi patients with active Rheumatoid Arthritis (RA) and the effects of drug therapy.
Patients and methods Fifty Iraqi patients with untreated active Rheumatoid Arthritis and 50 matched healthy control were studied with concentration on estimation of fasting serum Lipid profile which is repeated after 3month treatment with different disease modifying anti Rheumatic drugs (DMARDs) regimens.
Results Fifty Iraqi patients were included in this prospective study 47 females (94%) and 3 males (6%). The mean age of patients was (45±3.20).
fifty healthy individuals were included in this study as a control group 45 females (90%) and 5 males (10%) the mean age of the control group was
Background: Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease and the catheterization and angiography still considered (in most centers) as essential preoperative diagnostic step. This retrospective aimed at evaluating the catheterization and angiographic finding in our Iraqi patients with diagnosis of TOF
Patients and methods: The catheterization and angiographic study of200 patients with TOF-' referred to Ibn Al-Bitar Cardiac Center had been reviewed.
Results: There were 126 males and 74 females and their ages ranged from 11 months to 37 years. The catheterization data showed that 88% of the patients had equal LV and RV pressure. The evaluation of pulmonary artery pressure showed that all pati
Background &objectives: Angiogenesis plays an important role in the growth, progress and the metastasis of solid tumors. This study was done to determine the significance of angiogenesis as another prognostic factor in gastric carcinoma in an attempt to identify the patients at high risk of recurrences after surgical therapy who may benefit from postoperative adjuvant therapy.
In this study the correlation between the microvessel count(MVC) and the various clinicopathological factors was investigated. A highly significant statistical correlation was found between the mean microvessel count in different histological grades and the stage of gastric adenocarcinoma .
No correlation was found between the MVC and the age and sex of t
Background:
Background:
Background: Hirsutism is a common clinical problem which causes a great distress to the patient, which true incidence is unknown . However it is more common among Mediterranian women who are usually more accepting of their condition .
Aim of study : To determine the prevalence of hirsutism among adult females attendins the gynaecology out patient clinic at tikrit teaching hospital.
Patients & Methods: A sample of 175 adult non pregnant women (married & un married) with age range (18-25) years was included in this study .All attending the Gynaecology out patient clinic in Tiktrit teaching Hospital from Jan-Oct. 1999 .A full medical history was obtained. then patient were examined for pattern and severity of hair gowth . Grad
Background: Prechordal plate is important midline structure in the head region. It has been shown that it plays a bivotal role in the development of the brain and the eyes.
Aim of study: There is confunsion, in the literatures and textbooks concerning of terms: prechordal plate, prechordal mesoderm and the Buccopharyngeal membrane. The aim of this work is to study is based on histological changes of the early stages of the chick embryo hoping to illuminate these aspects especially after the recent revival of attention to the importance of this region in the process of induction of the brain region of the newral tub & the development of the prosencephalon & the eyes as shown by genes activities & expression in the prechorda
Background: The accumulation of the lipid in the vascular smooth muscle cell within the arterial intima is a key process of the pathogenesis of atherosclerosis. Atherosclerosis is a degenerative disease of blood vessels leading to stroke.
Materials & Methods.One hundred and ten patients with acute stroke were included in this study 88 patients with ischaemic or infarction stroke and 22 patients with hemorrhagic type ) as well as thirty apparently normal healthy subjects as controls.
Results.Triglycerides levels and AI only were statistically significant in ischaemic type of stroke (P<0.005) while other lipid fractions were similar to the control values.
Conclusion: Acute stroke patients (infarction type) had significantly
خلفية البحث: التهاب البنكرياس الحاد هو حالة التهابية حادة. إنه ليس مرضا غير شائع ، في كل من البلدان المتقدمة والنامية ، يسبب ارتفاع معدلات المراضة والوفيات ، وينطوي على عبء اقتصادي ثقيل. التهاب البنكرياس الحاد الشديد موجود في 25٪ من مرضى التهاب البنكرياس الحاد ، مع وفيات كبيرة. ساهمت التغييرات في علاج التهاب البنكرياس الحاد في العقدين الماضيين في خفض معدل الوفيات. هدفت هذه الدراسة إلى مر
... Show MoreBackground: To study prevalence and method of diagnosis of acute rubella Infection during early pregnancy in Iraq.
Patients and Methods: Clinical signs and symptoms of acute rubella infection were looked for in (170) pregnant women looked before (12) weeks of gestation .Serial rubella specific IgG and IgM serological testing was done in these (170) women before (12) weeks of pregnancy, after (3) weeks, and again at (18-20) weeks of gestation.
Results: Three woman had clinical signs and symptoms of rubella infection from (26) woman were IgM positive at (9) weeks of pregnancy; (94) were IgG +ve but IgM –ve initially and also on repeat sampling after (3) weeks; while (50) women were nonimmune (IgG and I
Back ground: A urinary tract infection is one of the most common diseases occurring from neonate up to geriatric age groups
Patients and Methods: A total of (100) Midstream urine (MSU) samples were collected from patients having signs and symptoms of Lower urinary tract infection. These patients were attending Urology Clinic, Ramadi General Hospital.
Result: Culturing of (100) MSU samples on MacConky and blood agar resulted in (5) types of bacteria which included: Escherichia coli (46%) and it was found the most frequent bacteria causing LUTI. This is followed by Klebsiella pneumonia (23%), Pseudomonas aeruginosa (13%), Proteus mirabilis (10%) and Staphylococcus epidermidis (8%).
Conclusion: Out of
Background: - Carcinoma of the lung has became the most common type of cancer since 1985 & the most common cause of cancer death in both males & females.
Aim of study: - To assess the diagnostic accuracy of bronchial wash cytology & application of immunocytochemical methods, using two tumor markers (low molecular weight cytokeratin & epithelial membrane antigen) for more accurate & precise diagnosis of lung tumors.
Patients, materials and methods: - Fifty fifes suspected lung cancer cases according to their clinicoradiological examinations were included in this study.
Bronchial wash cytology was performed for all the 55 patients. Smears were stained by conventional cytological stain i
Background:
Acute leukemias are clonal neoplastic proliferations of immature cells of the hemopoietic system. They are divided into acute myeloid leukemia (AML), acute
lymphoblastic leukemia (ALL) and acute undifferentiated leukemia (AUL). LDH has been suggested as a possible non-specific tumor marker for many years, and total serum LDH is
frequently elevated in neoplastic diseases. The aims of the study are to evaluate the significance of increased serum LDH levels in patients with acute leukemia and to
determine the importance of serum LDH level in the follow up and assessment of treatment responses.
Patients, Materials and Methods:
This study was conducted at Baghdad Teaching Hospital in Medical C