Leishmaniasis, a disease triggered by the parasitic protozoan Leishmania, is spread through the bite of infected female sandflies, specifically those of the Phlebotomus and Lutzomyia species. The body's defense mechanisms, both innate and adaptive, rely heavily on cytokines, a category of glycoproteins or modulatory proteins that orchestrate a crucial response to infection and disease. This study aimed to elucidate the relationship between serum IL-17A levels and single nucleotide polymorphisms (SNP) of IL-17A (rs2275913) with the susceptibility to cutaneous leishmaniasis. A total 200 samples of whole blood were collected form patients and controls at Baquba Teaching Hospital /Diyala Governorate/ Iraq from October 2022 to Februa

In this study, the heavy metals, polycyclic aromatic hydrocarbons (PAHs), micro-plastics (MPs), and their potential soil contamination in a specific area in Baghdad City, Iraq were studied. During February and June 2024, soil samples were collected from six locations (Agricultural, plastic factory, Oil factory soil, Barren soil, residential, and Landfill soil) within Baghdad City. The total concentration of heavy metals of Pb, Cu, Zn, Mn,, Cd, and Fe in the soil samples ranges between 3.27and 26.4, 12.9 and 33.6, 24.7 and 114, 319 and 715, 0.37 and 2.19 and 603 and5142 mgkg^-1 in the dry period, while it ranges between 3.07and 24.7, 12.10 and 31.51, 23.17 and 106.9, 299.2 and 690, 0.35and2.05 and565 and 4822 mgkg^-1 i

     The most prevalent cancer is breast cancer, and the incidence of breast cancer in women worldwide is increasing at a remarkably rapid rate. This study was conducted on 90 samples (45 newly diagnosed breast cancer samples and 45 control group samples), ranging in age from 35 to 70 years. Blood samples were collected from the Alawia Teaching Hospital and the Oncology Teaching Hospital between October 2020 and March 2021. ELISA assessed ROS, GPX, visfatin, IGF-1, vitamin A, leptin, and soluble al-Klotho. The results indicate that the breast cancer patients had significantly higher (ROS 3.57, visfatin 17.44) (ng/mL) (p<0.0001) and leptin 16.11 (ng/mL). In the group of patients, there was a significant increase (p<0.004) compar

Pre-eclampsia is a serious pregnancy complication marked by high blood pressure, typically exceeding 140/90 mmHg, that often emerges after the 20th week of pregnancy. It may be pronounced if there is a high risk for the mother or fetus. The importance of the placental growth factor (PlGF) in predicting preeclampsia has been established by earlier research. However, the study aims to evaluate the predictive accuracy of serum Placental growth factor in determining the severity of disease. The study involved 90 pregnant Iraqi women who developed preeclampsia after 24 weeks of gestation. Based on the magnitude of their hypertension biochemical parameters and, other symptoms, the women were categorized into two groups: 45 moderate cases and 4

     The mandibular first molar that has undergone endodontic treatment (ETMFM) may contain an additional canal that often goes unnoticed, known as the undetected second distal canal (USDC). While radiography is commonly used to identify the USDC in ETMFMs, its actual occurrence rate might differ when examined through histological methods. The prevalence of this canal was evaluated histologically through laboratory analysis and radiographically through cone beam computed tomography (CBCT). This study included 24 ETMFM from a total of 372 extracted mandibular first molars (MFM) from 372 Iraqi patients, which were collected from several private dental clinics in Baghdad city during 2022–2023. The extra canals, accounting for 6.45% of

The central focus of this investigation is examining the cytotoxic properties of various crude extracts derived from Ganoderma lucidum (G. lucidum) on human skin squamous carcinoma cells in vitro. The present study centres on three distinct extracts, namely, hot aqueous, cold aqueous, and ethanolic, all of which were prepared from G. lucidum sourced from DXN Company. The primary objective is to elucidate the potential inhibitory effects these extracts have on the proliferation of human skin squamous carcinoma cells. To achieve this goal, the extracts were subjected to analysis using GC-MS technology. The colorimetric assay method also played a critical role in assessing cytotoxicity (inhibition rate) and cellul

This paper deal with a technique of approximation which is insert to find the solution of a new type of couple system of constant coefficients parabolic equations (CPS) from mixing the method of finite element of Galerkin (GFEM) “in the variable of space” with the finite differences method of implicit type (IFDM) in the variable of time. Therefore, the abbreviation IGFEM is utilized to express on the method named by implicit Galerkin finite element method (IGFEM(. In this method at each  discrete value of time , the CPS  convert into a Galerkin system of  algebraic equations (GLAS) and later it is resolved by utilizing the method of  Cholesky Decomposition (ChDeM). Examples of explanations are awarded and the illustration for the

Nickel (Ni) is considered a toxic heavy metal that causes serious diseases in humans and animals. Therefore, this study was conducted on common carp, which is considered an essential food item for humans. The present study aimed to investigate the effect of nickel exposure on the gene expression of glutathione peroxidase and metallothionein in common carp (Cyprinus carpio L.1785 (Common carp)), focusing on the effects observed after 3 and 6 weeks of exposure. The experimental fish's morphometric features were noted. All fish were stocked, regardless of gender.  Fish were subjected to varying concentrations of 20, 40, 68, 80, and 100 mg/L to obtain the LC50 for Ni during 96 hours which was 80 mg/L through 96 hours.  Additionally, the fi

The estimation of the stress–strength model is perhaps one of the most challenging concepts in reliability analysis. Therefore, in this paper, a new metaheuristic algorithm (BAT algorithm) is used to estimate the Stress strength reliability system for the generalized inverse Pareto distribution. Furthermore, some  statistical properties for generalized inverse Pareto distribution are derived. In a 
simulation study, the BAT algorithm and the classical Maximum Likelihood (MLE) method are compared using the Relative efficiency criterion. The results show that the BAT variant estimates the parameters more accurately than the MLE.

This study examined the fnbA gene, which plays a role in biofilm formation, in Staphylococcus aureus bacteria that were exposed to copper nanoparticles (CuNPs) produced using an aqueous extract from the leaves of Myrtus communis and Nerium oleander plants. A total of 54 S. aureus bacteria were isolated from wastewater samples. Gene expression analysis was conducted using a quantitative RT-PCR readyMix apparatus with a classical conventional PCR model of BIOER – Germany. The cDNA samples from S. aureus bacteria and fnbA gene were quantified using quantitative real-time PCR by applying SYBR green using a two-step RT-PCR method to determine the effect of CuNP

Workers in automotive repair shops are at risk of exposure to hazardous chemicals, which can have varying health consequences depending on the duration and intensity of exposure, and may ultimately contribute to environmental pollution. The objective of this study is to identify variations in the biochemical levels, including liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), lipid profile, and atherogenic indices (AIP) between workers in car mechanics workshops and occupationally unexposed participants in Baghdad. Blood samples were taken from 70 workers aged 18–50 at car mechanics workshops. The occupations included car maintenance (WI, n = 35), vehicle painting (WII, n = 35), and healthy males (C, n = 25

A novel benzothiazole derivative compound, [M1], was synthesized by reacting 4-aminoacetophenone with 2-aminobenzothiazole in the presence of glacial acetic acid as a catalyst, enabling the efficient formation of the target compound. Amic acid compounds [M2-M4] were synthesized from the reaction of compound [M1] with various cyclic anhydrides in dry acetone. Cyclic imides derivatives were synthesized by a dehydrated reaction of the prepared amic acid [M2-M4] with acetic anhydride and sodium acetate to produce the corresponding cyclic imides [M5-M7]. The synthesized compounds [M5-M7] reacted with Acetyl chloride to produce the corresponding acetamide derivatives compounds [M8-M10]. The polyether derivatives [M11-M13] were synthesized from

Image denoising is a computer vision task that mainly aims to remove unwanted noise from a given image while preserving all necessary details and related information. Detection of edges and smooth image generation are required criteria for measuring the quality of the image denoiser. This paper introduces a new model for image denoising based on total variation (TV). The unprecedented novelty total variation (NTV) model combines norm-based total variation (TV) and  norm-based TV regularization. This paper uses the implicit finite difference method to solve the NTV model numerically. The statistical measurements are used to compare the results obtained using the NTV model with those obtained using other models, which show the superiority

This study examines the problems with the assessment of river water quality, which is affected by multiple water quality parameters (WQPs) that have inherent uncertainties and uneven decision-maker judgments. To cope with these uncertainties, we use soft sets, fuzzy sets, and fuzzy soft sets. In particular, we first present the square root mean square (SQRTMS) and a water pollution score (WPS) for fuzzy soft sets and propose a novel water pollution assessment framework, i.e., the fuzzy soft multi-criteria group decision-making model (Ω-model). This model produces Ω score, a weighted water pollution score, to classify pollution levels. The proposed methodology is made on water quality indices of Haora River in Tripura India, which ser

Assessing landslide susceptibility is paramount in planning, implementing management plans, and mitigating risks in areas vulnerable to this hazard. The present study, based on the Analytical Hierarchy Process (AHP) and Frequency Ratio (FR) in conjunction with Geographic Information Systems (GIS), aims to evaluate landslide susceptibility in the Oued Lebene watershed. Eleven causal factors determining landslides were considered, including elevation, slope, aspect, curvature, relative relief, lithology, precipitation, and distance to drainage, distance to road, NDVI, land use, and vegetation cover. By applying AHP and FR methods, a correlation between previous landslides and triggering factors was established to assess their influence on

In this study, nickel oxide nanoparticles (NiO-NPs) were synthesized using 
nickel nitrate hexahydrate and licorice leaves extract, which served as both a 
reducing agent and a capping agent. The optical, structural, and microscopic 
properties of the NiO-NPs were characterized using a range of techniques, including 
UV-visible spectroscopy, Fourier transform infrared spectroscopy, energy
dispersive X-ray analysis, field emission scanning electron microscopy, and atomic 
force microscopy. The bio-reducing potential of Licorice leaves was examined 
using gas chromatography-mass spectroscopy for phytochemical analysis of plant 
extract. Furthermore, cell cytotoxicity investigation was conducte

     Stable isotopes of water have many environmental benefits and applications, including water management to determine the origin of water, the age of ground waters, and the main pollution sources. An analysis was conducted on stable isotopes δ¹⁸O and δ ²H in rain samples obtained from a single location in Baghdad between 2013 and 2023. A statistical study was employed to determine the factors that affect the spatial and temporal isotopic fluctuations in rainfall. This work aimed to examine the impact of temperature, humidity levels, and precipitation rates on the isotopic composition of precipitation in Baghdad. The results showed that the MWL of Baghdad city, with a d- excess value of 12.69 , was higher th

     According to the high operational costs, low stability, and reusability of enzymes, immobilization by nanoparticle gathering has increased in recent years. Iron oxide nanoparticles (magnetite nanoparticles, Fe₃O₄) have been prepared by mixing one volume of iron dioxide ions and two volumes of iron trioxide ions with HCl via the precipitation of iron salts by NH₄OH. The features of magnetic nanoparticles have been studied by Atomic Force Microscopy (AFM), X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy, and Scanning Electron Microscopy (SEM). The prepared Fe₃O₄ was used in the adsorption method to immobilize the galactosidase enzyme. The immobilized enzyme has been compared wi

      Detecting protein complexes in protein-protein interaction (PPI) networks is a challenging problem in computational biology. To uncover a PPI network into a complex structure, different meta-heuristic algorithms have been proposed in the literature. Unfortunately, many of such methods, including evolutionary algorithms (EAs), are based solely on the topological information of the network rather than on biological information. Despite the effectiveness of EAs over heuristic methods, more inherent biological properties of proteins are rarely investigated and exploited in these approaches. In this paper, we proposed an EA with a new mutation operator for complex detection problems. The proposed mutation operator is formulated und

     This research aims to predict new COVID-19 cases in Bandung, Indonesia. The system implemented two types of deep learning methods to predict this. They were the recurrent neural networks (RNN) and long-short-term memory (LSTM) algorithms. The data used in this study were the numbers of confirmed COVID-19 cases in Bandung from March 2020 to December 2020. Pre-processing of the data was carried out, namely data splitting and scaling, to get optimal results. During model training, the hyperparameter tuning stage was carried out on the sequence length and the number of layers. The results showed that RNN gave a better performance. The test used the RMSE, MAE, and R2 evaluation methods, with the best numbers being  0.66975075, 0.470

The presented investigation, here, was carried out to understand the status of the blood parameters, before and after deworming of Toxocara infection in dogs. For performing the study, 15 pet dogs were recruited from some residential areas in Al-Diwaniyah Province, Iraq. These dogs were exposed to fecal-microscopic based detection of Toxocara eggs and hematological based evaluation of white blood cell (WBC), red blood cell (RBC), and differential counts before and 10 days after treatment with tetramisole. The helminth eggs in the feces of dogs were detected by the flotation method. In case of egg detection, deworming was carried out with tetramisole. The results revealed that the egg number was significantly (p˂0.05) decreased

     Nowadays, a strong relationship between the agriculture sectors and digital technologies is really interesting. The article describes how recent intelligent technologies can improve agricultural fields. Mobile applications are software programs created on smartphones, tablets, and computers. Agricultural fields mainly represent the pillar of the economy and the business sector that fulfills the world's food requirements. The United States has a valuable rank in potato production, which depends on this production economically.

Nevertheless, so many insects affect potato yield production quantitatively and qualitatively. So, a smartphone App was created to help potato growers diagnose insects that directly attack potato cro

     The goal of this paper is to construct the linear code, and its dual which corresponding to classification of  projective line PG(1,31), we will present Some important results of coding theory, the generator matrix of every linear code in PG(1,31) is found,  A parity check  matrix is  also found . The mathematical programming language GAP was a main computing tool .

      In this paper, we consider new subclasses     of meromorphic uniformly of multivalent functions in    with fixed second coefficient, we obtain the estimation of coefficients, distortion theorems, closure theorems and some other results.

     This paper is concerned with a Holling-II stage-structured predator-prey system in which predators are divided into an immature and mature predators. The aim is to explore the impact of the prey's fear caused by the dread of mature predators in a prey-predator model including intraspecific competitions and prey shelters. The theoretical study includes the local and global stability analysis for the three equilibrium points of the system and shows the prey's fear may lead to improving the stability at the positive equilibrium point. A numerical analysis is given to ensure the accuracy of the theoretical outcomes and to testify the conditions of stability of the system near the non-trivial equilibrium points.

Colorectal cancer (CRC) Patients showed different expression patterns of miRNAs which are involved in carcinogenesis in comparison to healthy controls individuals, miRNAs are involved in tumor progression and development of metastases. We investigate the expression profile of microRNA 320 and to quantify the expression level abundance among colorectal cancer patients in comparison to the healthy control group. The A total number of 60 plasma samples was collected from CRC patients along with 40 plasma samples from healthy controls and subjected to relative quantification using qPCR assay with a specified set of primers designed using s

      Field trial was conducted with the aim of utilizing extract of allelopathic crop to reduce the use of synthetic herbicides in wheat fields. Sorghum extract at 12 L /ha, sunflower extract at 12 L /ha, combination of sorghum and sunflower extracts at 12 L /ha and chevalier at 25, 50 and 100% of recommended dose were applied alone or in combination with each other. Weed free and weedy check treatments were included for comparison. The experiment was conducted in a randomized complete block design with three replications. The results showed that the recommended  dose of chevalier  treatment recorded lowest means of weed density 15.7, 23.7, 25.3 and 27.9 weeds m^-2and weeds dry weight 13.4, 16.4, 23.3 and 29.2 g m^-

      This paper intends to initiate a new type of generalized closed set in topological space with the theoretical application of generalized topological space. This newly defined set is a weaker form than the -closed set as well as -closed set. Some phenomenal characterizations and results of newly defined sets are inculcated in a proper manner. The characteristics of normal spaces and regular spaces are achieved in the light of the generalized pre-regular closed set.

With simple and undirected connected graph Φ, the Schultz and modified Schultz polynomials are defined as  and , respectively, where the summation is taken over all unordered pairs of distinct vertices in V(Φ), where V(Φ) is the vertex set of Φ, degu  is the degree of vertex u and d(v,u) is the ordinary distance between v and u, u≠v. In this study, the Shultz distance, modified Schultz distance, the polynomial, index, and average for both have been generalized, and this generalization has been applied  to some special graphs.

     In this work, combining acyclovir with ciprofloxacin (CCP), a new Schiff base and its metal complexes with iron (III), manganese (II), copper (II), zinc (II), and calcium (II) ions are synthesized and structurally characterized by XRD, SEM, ¹H NMR, ¹³C NMR, FT-IR, and UV-Visible spectral techniques. Furthermore, molecular docking studies were carried out, and the complexes were tested to resolve any potential hang-ups in opposition to the Herpes virus and DFT calculation studies. In addition, the metal complexes and ligand were screened against antibacterial strains of one gram-positive bacteria (Staphylococcus aureus) and three gram-negative bacteria (