major goal of the next-generation wireless communication systems is the development of a reliable high-speed wireless communication system that supports high user mobility. They must focus on increasing the link throughput and the network capacity. In this paper a novel, spectral efficient system is proposed for generating and transmitting twodimensional (2-D) orthogonal frequency division multiplexing (OFDM) symbols through 2- D inter-symbol interference (ISI) channel. Instead of conventional data mapping techniques, discrete finite Radon transform (FRAT) is used as a data mapping technique due to the increased orthogonality offered. As a result, the proposed structure gives a significant improvement in bit error rate (BER) performance. The new structure was tested and a comparison of performance for serial one-dimensional (1-D) Radon based OFDM and parallel 2-D Radon based OFDM is made under additive white Gaussian noise (AWGN), flat, and multi-path selective fading channels conditions. It is found that Radon based parallel 2-D OFDM has better speed and performance than serial 1-D Radon based OFDM.