The research aims to identify the effectiveness of using neural branching thinking strategies in developing reading comprehension skills for 10th-grade school students. To achieve this goal, the researchers adopted the quasi-experimental approach. The researchers used the reading comprehension skills test, in which the intervention lasted for 6 weeks. The research was conducted in Oman's first semester of the academic year 2024/2025. A sample of 70 students was divided into two groups: the experimental group, which was taught using the neural branching thinking strategies, numbered 35 students, and the control group, which was taught using the traditional method, numbered 35 students. The results showed the effectiveness of using neural branching thinking strategies in developing reading comprehension skills, and the experimental group revealed their capability to respond to reading comprehension skills questions. The research came out with several conclusions and recommendations.