TiO₂ famous the very best uranium elimination performance due to its excessive surface region, chemical balance, and photocatalytic effectiveness. Titanium dioxide (TiO₂) has proven promise as a photocatalyst and adsorbent for disposing of uranium from radioactively contaminated water. The goal of this study was to synthesize and evaluate TiO₂ nanoparticles for uranium removal from radioactively infected water using sol–gel and hydrothermal techniques. Under top-quality conditions, the synthesized TiO₂ done uranium removal efficiencies exceeding 70%, demonstrating its potential as a fee-effective and environmentally friendly fabric for radioactive wastewater treatment. The synthesis and amendment of TiO₂ to improve uranium adsorption overall performance is the principal focus of this investigation. To discover an excellent method for producing nano-composed TiO₂ with advanced surface characteristics, several synthesis techniques, which include sol-Gel and Hydrothermal have been investigated. The effectiveness of uranium removal was drastically studied on the subject of elements, including pH, temperature, touch time, TiO2, and crystal form (anatase vs. Rutile). According to the information, the TiO₂ reveals the best uranium elimination efficiency when synthesized in an acidic environment with anatage dominance; under ideal occasions, this output can reach over 70% performance. Through using middle wastewater, our work exhibits TiO₂ as a long-lasting and low-cost medium for uranium removal.