The objective of this study is to evaluate plasma levels of total Sialic acid TSA and Lipid –associated Sialic acid LSA as a marker of Rheumatoid Arthritis AR. Plasma Sialic acid is known as a parameter of inflammation. In the present study, in order to explore the potential role of sialic acid in arthritis rheumatoid, plasma sialic acid levels, plasma LSA and total protein in patients with arthritis rheumatoid were measured. A total 40 patients were compared with 40 healthy control subjects. Plasma TSA, LSA and TP level were determined spectrophotometrically in plasma samples. Plasma Sialic acid levels were significantly increased in RA (88.48±14.15 mg/dl, P<0.05) and LSA level were significantly increased in RA (26.37±2.25 mg/dl, p<0.05). By contrast there wasn’t any significant elevation of TP in RA patients, compared with healthy control (TSA,53.31±7.58 mg/dl, P<0.05), (LSA,18.46±1.45 mg/dl) and (TP, 7.39±0.34 g/dl).
S rum total. siic acid (TSI\) ·and lipid bound sialic acid {LSA) levels were detennined by spec.tr0photoinetric me(hods in 23 patients with oral cavity cancer(OCC). Of them 5 patients· have carcinoma ·of the anterior 2/3 of the tongue with an avetage age of { 60±8:0 year:;;}' and 2 males patients with carcinoma of the inner surface of the cheek with an average age {68±8.0 years·} and 8 patients had carcinomtl of rhflo"Qr of the mouth ,y-tt.h an av.erage {'62±9.0 ye.ars} a11d 8 patients with carcii1otna of the hard palate with an average age {58±8.0 years}. They were compated witn 32 healthy controls; &
... Show MoreForty patients with acute lymphoblastic leukemia(ALL) were tested for the serum levels of total sialic acid(TSA) and the immunoglobulins before and after treatnemnt with six diffrent chemotherapy protocols while significantly
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder . PCOS affects 6–10% of women during their reproductive life. Patients with PCOS are in the high risk for coronary heart disease because of their abnormal lipid profile, insulin resistance and obesity. The present study aimed to shed a light on the contribution of sialic acid, paraoxonase and immunoglobulin G as a clinical indicator in the pathogenesis of PCOS. Seventy five female patients with age range (16-38) years taken from Al-Sadder Teaching Hospital and AlZahrawi Hospital in Governorate of Messan through the period from July 2013 to December 2013 and twenty five apparently health subject as a control group were
... Show MoreIn this study serum total sailie acid concentration were tested as a scrological marker of discases activity to cvalute the result of the test in the diagonosis oe enteric fever(TSA) was measured in the serum od (50) patines with typhi fever(50)pa-tients
The aim of this research is to shed some light on the level of
serum total sialic acid (TSA) in individuals with typhoid fever. The individuals were at age of (35-45) years old and (TSA) was measured by resorcinol reagents. The results showed significant reduction in (TSA) compared to control or normal individuals.
Background: Diabetic retinopathy is an important complication of diabetes mellitus. It is supposed that elevated sialic acid in diabetes mellitus plays an important role in diabetic retinopathy. This study investigated serum total sialic acid levels related to glycemic control, blood pressure, retinopathy, and serum lipid level in diabetic retinopathy patients.
Patients & Methods: Type 2 diabetic patients aged (56.47±10.68) years were recruited for the study. Fasting venous blood samples were collected from 132 diabetic subjects of whom 79 without retinopathy and 53 were diabetic with retinopathy. All the blood samples were processed for serum total sialic acid (TSA), fasting serum glucose (FSG), HbA
The study dosage ethanol in the total content of acid sialic TC and acid sialic associated fat (LBSA) in blood serum and congener brain Dkor Jerd eggs study included dosage 20 animals of male rat Ald ethanol daily for a period of four weeks and concentrations 20% and 30%, 40%, 50% and size of dose 5mlThe results of the study showed that levels of TSA homogeneous in the brain and blood serum significantly reduced Ankhvaza
Background: Total serum sialic acid (TSA) and lipid associated sialic acid (LSA) have not been measured yet in depressive disorders.
Aim :The present study was undertaken to show if there is any change in the concentration of different forms of sialic acids in patients with depressive disorder.
Methods: TSA and LSA levels have been estimated in serum of 72 patients with depression, in addition to 50 healthy controls .
Results reflect a significant increase (p<0.05) in the TSA and BSA in the depressed patients as compared with healthy controls.
Conclusions: It could be concluded that TSA and BSA could reflect an immune like response to depression associated with increase in the sialylation of differ
To follow up the response of acute lymphoblastic leukemic
(ALL) patients to chemotherapy treatment and for prognosis, diagnosis, the total Sialic acid (TSA) levels was studied as a tumor marker. The study included 40 patients (male = 22, female =18) with (ALL) were tested for the serum and leukocytes homogenate concentrations of total sialic acid (TSA) before and after treatment with six different chemotherapy protocols. &n
... Show MoreThe aim of this study was investigating the correlation between elevation of Prolactin levels and the increase of the concentrations of total sialic acids. The study was performed on 149 women consisted of 93 infertile hyperprolactinimic women (patients), age ranged16-38 years old, and 56 normoprolactinemic women as a control group, 18-37 years old. Serum prolactin (PRL) and gonadotroph hormones (Follicle stimulating hormone FSH and Luteinizing hormone LH) were measured using enzymatic immunoassay (EIA) method, resorcinol method for serum total sialic acids (SIA). Patients were divided into four groups, each group represented the level of prolactin of infertile women as follow: G1= (21-30), G2= (31-40), G3= (41-50), and G4= (51-60) ng/mL. S
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