The study aimed to introduce the effect of Giardia lamblia infection on changes in
some biochemical parameters in serum of infected patients before and after treatment during a
period of one year, (from Feb, 2008 to Jan, 2009).
Samples of 50 infected patients who referred to Al-Kadimiyah Teaching Hospital,
were collected before and after 7 days of treatment.
The activity of liver enzymes (Gpt and Got) before treatment increased significantly as
it reached up to (8.47) u/L and 19.06 u/L, comparing with control values (6.455) u/L and
(8.39) u/L respectively. The activity of the enzymes decreased after treatment but the values
of Gpt and Got remained higher than the control values as reached 7-27 u/L, 11-64 u/L.
The concentration of creatinine before treatment significantly increased slightly
(p<0.005) and reached (0.75) mg/dl then it decreased after treatment and reached 0.73 mg/dl
comparing with control 0.618 mg/dl.
Also, slight increase in the concentration of Na
+
before treatment as it reached 144.4
mmol/L then decreased after treatment and reached 136.3 mmol/L comparing with control
138.2 mmol/L high significant increase (p<0.005) in the concentration of K
+
before treatment
as it reached 5.02 mmol/Lit decreased after treatment and reached 4.03 mmol/L comparing
with control values 3.86 mmol/L significant decrease (p<0.01) in the concentration of Iron
before treatment as it reached 13.73 mmol/L comparing with control values 23.0 mmol/L then
it increased after treatment and reached 15.06 mmol/L.
Significant decrease (p<0.01)in the levels of vitamins (E, C and A) in all patients
serum before treatment as it reached 0.219 mg/dl, 1.28 mg/dl, 0.58 mg/dl comparing with
control values 0.332 mg/dl, 1.39 mg/dl, 1.06 mg/dl then it increased after treatment and
reached 0.328 mg/dl, 1.434 mg/dl, 1.11 mg/dl.