Dust can be considered as an important factor in environmental
pollution which has a direct eOect on human health. In this study ,we
attempted to eval uate serum oxidant -antiox idant balance in workers dust exposed continuously and also the effect of iron and silicon content in exposed dust on the mentioned balance .The study included tbrcc groups: A group included 20 workers of building block factories, B group included 20 workers in general company of grains production and C group included 15 healthy' subjects which represented control group. !ron and silicon contents in dust samples of two studied regions were measured. Higher levels of iron and silicon were found in A group region compared to B group region. Our results il lustrated a significant elevation in serum (MDA) l evcl(the index of lipid peroxidati on) for A group compared to Band C groups. Also, a significant decrease in semm
albumin level was found in A group compared to C group as well as · semm ceruloplasmin level in A group was found to be significantly elevated compared to 8 and C grou ps. A negative correlation was found between serum MDA and ser um albumin levels in A and B groups. Also
,positive correlations were found between senun MDA and each of serum ceruloplasmin and daily dust exposure time in A and B groups. These results provide a new conclusion that the iron and silicon content in prol onged exposed dust lead to disorder in serum oxidant - anti oxidant balance.
