The present study was conducted to measure the concentration of progesterone throughout gestation and parturition in control and treated bitches. Thirty anestrus bitches aged 3 - 6 years and weighing 19.5 - 26 kg were used in this study. The bitches were divided equally into three groups as follows: the 1st group as a control group without treatment, the 2nd group as a treated group anestrus bitches treated orally with 0.125 mg/kg BW bromocriptine (Parlodel) twice daily, and the 3rd group treated orally by 0.012 mg/kg BW cabergoline (Dostinex) until the appearance of estrus signs. The results showed that the number of responded animals were in proestrus bleeding and became pregnant and newborn 70%, 60% and 50% for control, bromocriptine, and cabergoline treated groups, respectively. In addition, there were no significant differences (P ≤ 0.01) in progesterone concentration between the control and treated pregnant bitches. It can be concluded that both medicines bromocriptine and cabergoline have no effect on progesterone levels during pregnancy period in bitches.
