The effect of temperature and pH on the stability of the antibacterial
“tilmicosin” was evaluated in this study. The temperature degrees studied were
25 , 45 and 65 oC each for 24 hours , while the pH values studied were 6 , 7 and
8 each at room temperature and for 24 hours also.
A microbiological assay method was employed for analysis of the collected
samples.
The results of analysis indicate significant drop in activity of the drug as a
results of exposure to temperature or pH.
The above mentioned results necessitate the maintenance of drinking water in
the storage depots of the field below 65 oC especially in summer season, so to
keep the chemical structure of the drug and to offer enough therapeutic
concentration to reach the tissue.