This study aimed to prepare a synbiotic of Sacch. cerevisiae and used as 0.1 and 0.2 % in feed (T2,T3) for reducing the experimental infection of Salmonella typhimurium to broiler chicks ( -6103days) by using 40 birds divided into four treatments , T1 was negative control with 0.1 % synbiotics and T4 was positive control with experimental infection only , production
and blood parameters were studied , and the results showed the following: A synbiotic of Sacch. cerevisiae was made which have 10 7 cfu of
Sacch. cerevisiae and 10 mg Mannan Oligosaccharide per gram .Using 0.1 and 0.2 % of Sacch. cerevisiae synbiotic reduced experimental infection of Salmonella typhimurium via increase body weight and feed conversion and
decrease mortality and physiological stress of experimental infection.
