Experiment study was done on the pathogenicity of Salmonella give infections in dogs . The
experiment was carried out on 8 puppies ranging in age from 8-9 weeks. The puppies were divided randomly
into two equal groups. Group I inoculated orally with 4.8x109 Salmonella give and group II saved as control.
The disease was characterized by acute gastroenteric and septicemic forms with variable severity. The most
consistent clinical signs were anorexia, fever, diarrhea, vomiting repression and recumbancy. Salmonella was
consistently isolated from blood as well as from feces. Gross pathological changes and histological
examination were characterized by sever congestion and inflammatory cells in the most of GIT