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jcovm-1183
The effect of two challenge doses of Dictyocaulus filaria on the acquired immunity of sheep vaccinated with "Filiraq".
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Twenty six lambs divided into four groups were used to study the effect of experimental infection with two challenge doses of D.filaria ( 100 & 300 larvae / Kg. B. W.) on the aquired immunity after vaccination with irradiated larval vaccine Filiraq. The clinical symptoms , eosinophi lic response, blood picture, faecal larval counts, gross pathological changes & adult worm counts in the lungs were studied ..

The results showed that a high dose of challenge (300 LI kg) prevents the development of expected acquired immunity, however the other vaccinated & challenged group ( 100 LI Kg B.W ) showed good level of acquired immunity in comparison with other group

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