Anti- nucleosome antibodies- a valuable test in systemic iupus erythematosus
systemic iupus erythematosus (SLE)
anti-nucleosome antibodies
anti-dsDNA.
Background: Nucleosomes are fundamental units of chromatin released by internucleosomal cleavage during cell apoptosis, and nucleosomal material has been demostraded in the surface blebs of opoptotic cells. recent studies have shown the presence of antinucleosome antibodies in systemicc lupus erythematosus (SLE).
