Background: Metabolic syndrome is a cluster of risk factors for atherosclerotic cardiovascular disease caused by abdominal obesity, such as hyperglycemia, hypertension, dyslipidemia, and insulin resistance.Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acidcatabolism. Adiponectin is exclusively secreted from adipose tissue into the bloodstream. Leptin, a hormone synthesized by fat tissue had been noted to regulate energy balance and metabolism.In this study investigated the relationships of adiponectin/leptin ratio with metabolic syndrome in apparently healthy Iraqi male adults.
Objective: This study was designed to investigate the relationship of adiponectin/leptin ratio with metabolic syndrome in apparently healthy Iraqi male adults.
Methods: Ninety male subjects were enrolled in study (mean age, 40.97 ± 7.94 years). Serum leptin level and adiponectin level were measured using an enzyme-linked immunosorbent assay. And the presence of metabolic syndrome was assessed.
Results: Mean leptinlevel was significantly higher (7.29 ± 0.38 ng/ml), whileadiponectin andadiponectin/leptinratio was significantly lower(4.78 ± 0.24 μg/ml; 0.74 ± 0.07) respectively in
subjects with MS. With increasingnumber of metabolic syndrome components, the mean values of leptinincreased and the adiponectin andadiponectin/leptindecreased.
Conclusion: adiponectin/leptinratio correlated well with the presence and number of metabolic syndrome components in Iraqi male subjects.
Background: Polycystic ovarian syndrome (PCOS) is a condition associated with chronic anovulation, and androgen excess. Clinically, PCOS women usually presents with menstrual irregularities, infertility, and hirsutism. Women with this syndrome are at increased risk of metabolic syndrome (MS).
Patients and Methods: This study was conducted during the period from March 2013 until the end of September 2013. A total of 50 PCOS women were studied (25 PCOS women with MS and 25 PCOS women without MS) with an age ranged from (35-45) years. Women with PCOS were referred to Medical City Hospital in Baghdad and compared with 25 healthy women as control group. Serum luteinizing hormone (LH), follicle
The co-occurrence of metabolic syndrome with type 2 diabetes mellitus (T2DM) will potentiate the morbidity and mortality that may be associated with each case. Fasting triglycerides-glucose index (TyG index) has been recommended as a useful marker to predict metabolic syndrome. Our study aimed to introduce gender-specific cut-off values of triglycerides- glucose index for diagnosing metabolic syndrome associated with type 2 diabetes mellitus. The data were collected from Baghdad hospitals between May - December 2019. The number of eligible participants was 424. National cholesterol education program, Adult Treatment Panel III criteria were used to define metabolic syndrome. Measurement of fasting blood glucose, lipid pro
... Show MoreBackground: Cigarette smoking is the leading avoidable cause of morbidity and mortality in the general population; however its effects on people with diabetes are even more profound. The adipocytokines leptin and adiponectin play an important role in regulating glycemia, lipidemia, endothelial dysfunction, and proinflammatory mechanisms .
Objective: We aimed to investigate the profile of adiponectin and leptin in type 2 diabetic smokers and non- smokers.
Patient and Methods: Ninety overweight males attending the Teaching Laboratories, Medical City were enrolled in this study, they were arranged as 30 diabetics non smoker, 30 diabetics smokers and 3
... Show MoreBackground: Poly cystic ovary syndrome is a common disorder in women of reproductive age, it is associated with disturbance of reproductive, endocrine and metabolic functions. The pathophysiology of PCOS appears to be multifactorial and polygenic. Leptin seems to play an important role in pathophysiology of PCOS especially in women with BMI ≥25kg/m2.
J Fac Med Baghdad 2014; Vol.56, No .2 Received Sept .2013 Accepted April. 2014 |
Objectives: To assess leptin
... Show MoreResearch on geopolitical and geopolitical studies relates to a range of sciences that can be called auxiliary sciences, such as political science, international relations in particular, and history, but their focus is rarely on science and ethnography
That the issues and problems of the world today has become so large and complex that does not allow a specific field or knowledge to solve one of the need for the newly known knowledge integration (geopolitics and geopolitics) in particular to move towards cognitive integration to understand many of the problems and global issues that faced The importance of this study comes to clarify the relationship between Darwinism, geopolitics and geopolitics. The geopolitics in modern terms d
... Show MoreBackground: Metabolic syndrome is a complex series of metabolic defects, characterized by high levels of serum glucose, hypertension, abdominal obesity, and dyslipidemia. The high mobility group AT-hook1, an architectural transcript factor, affects the homeostasis of glucose. No previous studies have been performed to examine whether HMGA1 can be secreted into the extracellular milieu.
Objectives: this case-control study aimed to examine whether HMGA1 secretes into the extracellular milieu and compares its serum level in two groups of metabolic syndrome (with and without diabetes) and a control group composed of apparently healthy individuals of Iraqi population with different nationalities.
... Show MoreBackground: Polycystic ovary syndrome (PCOS) is
the most common form of chronic anovulation
associated with androgen excess; it occurs in about 5
– 10% 0f reproductive age women. Metabolic
syndrome is characterized by insulin resistance,
hypertension, obesity, abnormalities of blood clotting
and dyslipidemia.
Adult women with PCOS have an increased
prevalence of the metabolic syndrome(MBS).
Objectives: To detect the prevalence of metabolic
syndrome in women with proved PCOS, attending the
Specialized Center for Endocrinology and Diabetes, in
Baghdad.
Materials and methods : A total number of 40
women with proved PCOS were included in this study
which was conducted in the Specialized Center f
Metabolic syndrome (MetS) is a combination of health disorders that mainly result from overweight and obesity. It increases the risk of developing cardiovascular disease and diabetes. (MetS) closely related to the existence weight gain or Obesity and laziness. It increases the serum levels of TNF-α and change the levels of a number of other parameters (e.g., adiponectin, resistin, and PAI-1). TNF-α dose not only appear to cause the production of inflammatory cytokines. It can trigger cell signaling by interacting with TNF-α receptors that can lead to insulin resistance. Usually, the digestive system molders the foods you eat and converts them to glucose. Insulin is an anabolic hormone produced by the pancreas that aids glucose g
... Show MoreBackground: Arm span is the closest physiologic measurement to standing height. Increased arm span to standing height ratio, which indicates a possible loss of height, due to aging, often results from osteoporosis-related vertebral collapse or other causes. This has possible consequences on lung functions.
Objective: To evaluate the effects of aging related loss of height to severity of dyspnea.
Method: Patients visited pulmonary function test laboratoryat Baghdad teaching hospital outpatient clinic department from first of November 2009 to thirty first of December 2010 for preoperative assessment were recruited to participate in our study. All recruited subjects were evaluated with a clinical history and physical examination follo
There is substantial data supporting the importance of both endogenous and exogenous estrogen in maintaining reproductive health and preventing chronic disease, androgens in women's health are rarely discussed. This is one of the first researches to investigate correlates of blood testosterone concentrations in women with osteopenia, in anticipation of the growing interest in the role of androgens in women's health. A 65 volunteer women were enrolled in the current study, they were divided into two groups, 35 postmenopausal women with osteopenia were in the first group, and the second group contained 30 postmenopausal women without osteopenia as a control. Blood samples were collected from all participants and analyzed for testosterone l
... Show More