Back ground: Hirschsprung`s disease is a common problem among pediatric population, many procedures had been implemented in the treatment with different results. In the last decades one stage transanal endorectal pullthrough (TEPT) had come into the stage as a minimal invasive choice for such condition with good results.
Objectives: To evaluate the feasibility and safety of TEPT procedure among pediatrics in a tertiary pediatric surgery center in Iraq.
Patients and Methods: A prospective study was conducted on 11 patients with Hirschsprung’s disease, attending Central Teaching Hospital of Pediatrics for the period from March 2007 till August 2014. Their ages were ranging from 1 month - 12 years. All cases had diverting colostomy and leveling biopsy. The aganglionic segment was confined to the rectum and rectosigmoid junction. TEPT was done to all cases with closure of colostomy 6-8 weeks after pullthrough. The patients were followed up for a period of 6 months-4 years.
Results: The study was conducted on 11 patients with a mean age of (33.7 ± 43.4 months); the male to female ratio was 9:2. Regarding the level of aganglionosis, it was confined to the rectum in 4 cases, while it reached the rectosigmoid junction in 7 cases. The mean operating time was (115.4 ± 23.5 minutes), and the mean volume of blood loss was (37.3 ± 17.6 ml). The average length of resected aganglionic segment was (13.9 cm). There is no conversion to laparotomy in any case. Complications developed in two cases one with perianal excoriation and the other develop postoperative enterocolitis.
Conclusion: Transanal Endorectal Pull-Through operation for Hirschsprung’s disease is feasible and safe, and it can be performed successfully in all ages of children with good results avoiding transabdominal exploration.
Background: Congenital pouch colon is an usual abnormality associated with anorectal malformation in which the colon is partially or totally replaced by a pouch like dilatation connected to the genitourinary tract by a fistula(colovesical).The condition varies from complete absence of normal colon with the ileum opening into colonic pouch to the presence of nearly normal colon with only the rectum or recto sigmoid being attached to a pouch which in turn connected to bladder by a band or fistula.
Objective: is to evaluate the methods of diagnosis and management of(C.P.C) with studying environmental factors especially pesticides and its prevalence.
Patients and Methods: A total number of seven cases of(C.P.C) associated with high typ
ABSTRACT:
Objectives: The study aims to know the effectiveness of the educational program in the patient’s adherence to medication and diet and to know the relationship between the effectiveness of the education program and their demographic data related to the patient’s age, gender, marital status, education level, occupation, monthly income and residence.
Methodology: A quasi -experimental design study was performed on patient who attended to Gastroenterology and Hepatology Teaching Hospital, from March 2021 to September 2021. The non-probability sampling including 50 patients for case study and 30 patients for control group. The questionnaire consists of 3 parts, part one the socio
... Show MoreBackground: Chronic subdural hematoma is a blood collection in the subdural space for more than 3 weeks from the onset of the bleeding. It is more likely to develop in infancy and after the age of 60 years. The incidence of subdural hematoma is 1- 2 per 100,000 people per year.
Objective: To delineate the most common feature aspects of SDH like age, predisposing factors, symptoms and signs and different types of management of the disease.
Patients and Methods: A prospective study of 40 patients from the period January 2012 - January 2014, and conducted in Gazi Al-Hariri Hospital of Surgical Specialties, disregarding the age, complaining of chronic subdural hematoma as proved by CT
Background :
Colorectal cancer (CRC) is the 4th common gastrointestinal cancer. (BRAFV600E) is a member of RAF family of serine/threonine protein kinases that function to regulate the (MAPK) / (ERK) pathway. BRAFV600E mutated CRC are associated with right-sided primary tumors, older women and high-grade tumors.
Aims of the study:
Study the immunohistochemical expression of BRAFV600E biomarker in a sample of Iraqi patients with colorectal cancer and the correlation of BRAFV600E expression with other clinicopathological variables such as patient's age and tumor gra
... Show MoreBackground: Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon that often extends to involve the remainder of the large intestine in a continuous manner. Intestinal amoebiasis can present as a chronic, dysenteric syndrome of diarrhea, weight loss, and abdominal pain that can last for years and mimic ulcerative colitis.
Objective: Studying the prevalence of E..histolytica by using serological method ELISA for their detection, Investigate the possible role of E.histolytica as a cause of blood, diarrhea in non-ulcerative colitis group &Comparison between serological detection of E.histolytica and stool examination.
Patients and Methods: Retrospective and prospective study was conducted
Background: Human colorectal carcinogenesis is a complex, multistep and multigenetic process. Matrix metalloproteinase-2 and cyclooxygenase-2 are key enzyme in degradation of extracellular material, are over expressed in several epithelia like colorectal adenocarcinoma.
Objectives: This study was designed to detect the expression of matrix metalloproteinase-2 and cyclooxygenase-2 in patients with colorectal carcinoma and their correlation with age, gender, tumor grade and presence or absence of muscle invasion.
Materials and methods: Immunohistochemical staining of MMP-2 and COX-2 was determined in 40 tissue samples from colorectal patients, from teaching laboratories in Baghdad medical city. In additi
Background: Colorectal is a worldwide health problem. Tumors stimulate the ground of host blood vessels, a process called angiogenesis, which is essential for supplying nutrients of the tumor, also stimulate the lymphatic vessels for metasatasis.
Background: Colonic cancer is a very common disease world-wide being fourth most common cancer characterized by abnormal proliferation of the inner wall of colon then taking full colon wall thickness then spreading to surrounding lymph nodes and tissues and finally distant metastasis. It is one of most complicated diseases with debilitating symptoms which becomes more sever , prominent and specific with advancing stage with high percent of fatality and relatively short survival if diagnosed late or if left untreated.
Objective: To evaluate the efficacy of serum CEA & sAPRIL levels in the diagnosis and screening of colon cancer and their validity for this.
Patients and methods: This study was applied on 35 patients with colonic
Neuroimaging is a description, whether in two-dimensions (2D) or three-dimensions (3D), of the structure and functions of the brain. Neuroimaging provides a valuable diagnostic tool, in which a limited approach is used to create images of the focal sensory system by medicine professionals. For the clinical diagnosis of patients with Alzheimer's Disease (AD) or Mild Cognitive Impairs (MCI), the accurate identification of patients from normal control persons (NCs) is critical. Recently, numerous researches have been undertaken on the identification of AD based on neuroimaging data, including images with radiographs and algorithms for master learning. In the previous decade, these techniques were also used slowly to differentiate AD a
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