Summary:
Background: Nitre I la sativa Linn is a well known herb that is used by different societies, as food additive and as a medicinal herb: it used as a galactagouge for lactating women, and has long been described as an abortifacient-emmenagouge.
Aim of the work: is to investigate the effect of crude black seeds on the endometrium and the pattern of it’s mucins, during the different phases of the Estrus cycle, making use of some special stains for the histochemical demonstration of mucins.
Materials <6 Methods.'Crude Nieella sativa Linn, seeds were administrated for ten days, by an orogastric tube, on single regular daily dosage to properly selected mature Norway albino female rats. Animats were subdivided into subgroups, according to phases of the estrus cycle. Utera of these animals were routinely processed for carbohydrate histochemical (d-PAS, d AB2.5-PAS & A li 1.0) studies using carnoy's fixative, paraffin embedded sections. Experimental specimens were compared with that of control subgroups.
Results: Results showed marked production of diastase fast-PAS reactive non-alcianophilic neutral mucins, with inhibited production of sulphated highly acidic mucins among the surface lining and the glandular epithelial cells, at Estrus. Effects of such changes in the pattern of endometrial mucins on the state of fertility, was discussed.
Background: complications of diabetes have become more common as the rate of diabetes. This complication includes liver and diabetic autonomic neuropathly.
Rifampicin (RF) considered a hepatotoxic drug. Is one of the first line successful drugs of management of tuberculosis. To reduce injury and protect liver from adverse effect of Rifampicin, this study was designed to investigate the activity of Nigella Sativa (NS) seeds powder aqueous suspension to hepato protection against Rifampicin.
For conducting this study,24 male albino rats were divided into four groups and all treated orally as follow; group І (control), received normal saline alone; group II, received RF (50mg/kg body weight/day); group III received NS it's called normal dose, (2g/kg body weight day); group IV RF (50mg/kg body weight) + NS (2g/kg body weight).Respectively for 28 days. Blood samples obtained for estimation of
Nigella sativa seeds (NSS) are reputed traditionally and scientifically as a potent agent that promote milk secretion (galactagogue), but their mechanism of action is studied trivially. One suggestion was that these seeds are bio-transformed to sex hormones within the ovaries. Therefore, this investigation was designated to throw light on the action of these seeds in the absence of ovaries i.e. in male rats. Thirty Norway male albino rats were used in this investigation. They were divided into experimental (n=20,fed NSS 2g/ Kg body weight /day for 14 days) and control (n=10, fed placebo for 14 days). After sacrifice mammary gland and blood samples were obtained. Experimental rats revealed a significant increase (p (0.01>in
... Show MoreChemical analysis for evaluation of Nigella sativa L. (black cumin) seeds showed a composition of Fat 39% ; Protein 28% ; Carbohydrate 21% ; Moisture 6% and Ash 4.5% . It was found that the black seed contains the following mineral element : Magnesium 0.26 gm /100gm seed ; Calcium 0.25 gm /100gm seed and Iron 25 ?g / gm /100gm seed ; zinc 4.51?g /gm /100gm seed and Copper 3.60 ?g /gm /100gm seed. The analysis also showed that mineral element I. e. ; lead ; Cobalt ; Nickel ; Chrom ; Cadmium and Aresenic are not present . It was found that the fat of the black seed contains the following fatty acids : Myristic 2.8%; Palmtic 16.6%; Stearic 0.8 % ; Oleic 13.79% ; Linoleic 64.2% and Arachidic 1.9% .
The present study included experimental effect of Metronidazole drug and Alcoholic extract of Nigella sativa seeds on T. vaginalis that cultivated on i i Results showed that the numbers of parasite began increasing during a period after 24-48 hrs then began decreasing after 72-96 hrs, so that 72 hrs from growth considered logarithmic phase of T. vaginalis growth. Present results showed poisonous effect of N. sativa alcoholic extract that was prepared in laboratory and imported at concentrations (450, 550, 650 and 750) mg/ml on T. vaginalis by observing gradual decrease of trophozoite numbers with concentrate increase of extra
... Show MoreBackground: Nigella sativa seeds have been frequently used in folk medicine for treatment of various diseases such as inflammatory disease. The aim of this
study is to show the effect of this herb on Neutrophils count as the main antiinflammatory cells.
Materials & Methods: Aqueous & oil extract ofNigella sativa seeds have been applied for treatment of 30 blood samples of apparently
healthy individuals. Blood count has been performed after different incubation periods.
Results & Conclusions: This study revealed that treatment of blood samples with herbal extraction results in highly significant elevation of Neutrophils'
count with time passing particularly the aqueous one and
Two field experiments were performed to study the response of two species , Nigella sativa L. and Nigella arvensis L. within different sowing dates at spring and autumn seasons which included 1st and 20th March, 10th April and 1st May for spring season, while the sowing dates for the autumn season were, 2nd November, 21st November, 11th December, 31stDecember and 20thJanuary. Both experiments conducted according to the Completely Randomized Block Design (CRBD) within three replications at hallabja/Kurdistan Region, located [35°12'48.7"N; 45°57'34.4"
... Show MoreBackground: Palmoplantar psoriasis is a therapeutically challenging condition that can significantly impact patient quality of life as it directly affects activities. However, despite this impact, few clinical studies address treatment. Herbs and their extracts have been used for treatment of skin disease for centuries. One of the most popular herbs in our society is black cumin or seed of blessing oil (Nigella Sativa); this plant had diverse clinically useful activity.
Patients and Methods: This study was conducted in the Department of Dermatology and Venereology in Baghdad Teaching Hospital, Iraq during the period between January and October 2003. In this singleblind randomly controlled therapeutic stud