Background: Alcohol remains the single most significant cause of liver disease throughout the Western world, responsible for between 40 and 80% of cases of cirrhosis in different countries. Many of the factors underlying the development of alcoholic liver injury remain unknown, and significant questions remain about the value of even very basic therapeutic strategies.
Patients and Methods: In a cross sectional study, 113 alcoholic patients with evidence of liver disease in the absence of other significant etiology attending the Gastoenterorology and Hepatology Teaching Hospital between December 2001 and December 2003 were studied for the hematological and biochemical spectrum of alcoholic liver disease including Alfa fetoprotein (AFP) and gamma glutamyl transpeptidase alteration.
Results: The serum aminotransferase was mildly elevated and the AST/ALT ratio often exceeds 2.The serum bilirubin and PT positively correlated with the severity of ALD. The GGT was
commonly elevated irrespective of liver damage. AFP was bellow normal in (80%) and was negatively correlated with the severity of ALD.
Conclusion: The hematological profile of ALD was macrocytosis and neutrophile leukocytosis. The serum aminotransferase was mildly elevated. The GGT was commonly elevated irrespective of liver damage. AFP was bellow normal in the majority and is negatively correlated with the severity of ALD.
Background: Alcohol remains the single most significant cause of liver disease throughout the Western world, responsible for between 40 and 80% of cases of cirrhosis in different countries. There are no characteristic sonographic features of ALD. Many of the factors underlying the development of alcoholic liver injury remain unknown, and significant questions remain about the value of even very basic therapeutic strategies.
Patients and Methods: A total number of 50 patients with ALD were studied. Abdominal Doppler ultrasonography to determine the ratio of the left to right portal vein (PV) was done. They were compared with 50 healthy persons (control) and 50 patients with comparable CLD due to other causes.
Results: The diameter o
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Abstract: non-alcoholic fatty liver disease (NAFLD) is one of the widespread chronic liver diseases; it is ranging from simple fat buildup in the liver (steatosis) to non-alcoholic steatohepatitis (NASH) presence of inflammation and hepatocyte injury. &nb
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Non-alcoholic fatty liver disease (NAFLD) is one of chronic liver and defines by fat accumulation ≥5% in liver which can progresses to non-alcoholic steatohepatitis (NASH). NAFLD related to obesity as well as non obese individuals. Adiponectin is a cytokine secreted from adipose tissue involved NAFLD pathogenesis and liked with obesity. Irisin is a myokine, has a convenient effect against metabolic diseases such as obesity, disylipemia diabetes type 2 and reversed liver steatosis and may be related with NAFLD.
Vitamin D is one of the fat soluble vitamins and more precisely as a pro-hormone through its metabolite (1,25(OH)2 cholecalciferol) the major steroid hormone. After the skin exposure to the light, vitamin D un
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Non-alcoholic fatty liver disease (NAFLD) is one of chronic liver and defines by fat accumulation ≥5% in liver which can progresses to non-alcoholic steatohepatitis (NASH). NAFLD related to obesity as well as non obese individuals. Adiponectin is a cytokine secreted from adipose tissue involved NAFLD pathogenesis and liked with obesity. Irisin is a myokine, has a convenient effect against metabolic diseases such as obesity, disylipemia diabetes type 2 and reversed liver steatosis and may be related with NAFLD. Vitamin D is one of the fat soluble vitamins and more precisely as a pro-hormone through its metabolite (1,25(OH)2 cholecalciferol) the major steroid hormone. After the skin exposure to the light, vitamin D undergoes to
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Background: Autism spectrum disorder (ASD) is a general term for a group of complex disorders of brain development; these disorders have no single known cause, they are characterized, in varying degrees, by difficulties in social interaction, verbal and nonverbal communication and repetitive behaviors.
Objective: The aim of the study was to evaluate different biochemical parameters in some autistic Iraqi children, and to compare the results with healthy children who matched with age, looking for any alteration in the studied parameters in order to understand the biochemistry of this disorder.
Patients and Methods: Forty one consecutive autistic children admitted to (Al Safa center for autism and Iben- AL Rs
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This study was conducted in Baghdad, Iraq from December 2021 to May 2022. The goal was to determine the effect of Toxoplasma gondii on liver function by examining the relationship between Toxoplasma infection and hormones. One hundred and twenty male patients with Chronic liver disease (CLD) (age:14-75 years) and 120 control males (age: 24-70 years) participated in this study. Serum samples were taken from all individuals and were then analysed for anti-Toxoplasma antibodies. Hormonal tests were conducted for all participants which included (Cortisol, testosterone, prolactin, insulin, and thyroid-stimulating hormone TSH). Biochemical tests included (Prothrombin time PT, international normalized ratio INR and albumin); liver enzymes
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Background: To elucidate distinctive CT imaging features that allows a diagnosis of hepatic hydatidosis.
Patients and methods : The computed tomographic (CT) findings of 58 patients with sonographically detected cystic liver lesions were prospectively analyzed. These patients were
followed up until a final diagnosis was reached.
Results : By CT scanning we correctly localized and diagnosed 81 hepatic hydatid cysts in 50 patients. These were all proved by surgery or endoscopic retrograde cholangio-pancreatography (ERCP). Stage III and II hydatid cysts were the commonest types (29 % and 25 % respectively ). 52 % of the cysts were 5-10 cm at presentation. At CT, we identified some ancillary imaging fea
One of the most common public liver diseases over the world is fatty liver which contain alcoholic and non-alcoholic fatty liver. One-fourth among general population are impact Non-Alcoholic Fatty Liver Disease (NAFLD) in the worldwide.Retinol binding protein 4 (RBP4) is known as an adipokine, mainly synthesized and secreted from the liver and form adipose tissues. RBP4 acts as a transporter and specifically bound to retinol from liver to others tissues. Visfatin is an adipocytokine and mainly produced from visceral fat tissue, skeletal muscles as well as liver. Vitamin A absorbed, transported as retinyl esters to the liver then hydrolyzed to the retinol form and storage in hepatic stellate cells (HSCs) after reesterified with rigly
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