Background: Study the correlation between the left ventricular end diastolic volume (LVEDV), ejection fraction (EF) and the development of arrhythmia.
Patients and methods: Two hundreds patients with documented acute coronary syndrome and myocardial infection with dysrhythmia documented by ECG and holter monitoring assessed at the cardiac department at Baghdad teaching hospital over the period Jan-Dec 2007. These dysrhythmias were corelated with left ventricular end diastolic volume and ejection fraction.
Results: The patients were divided into 4 groups according to LVEDD and EF. The 1st group, 40 patients (20%) found to have non sustained ventricular tachycardia was associated with higher LVEDD (62-72mm) and low EF (30-39%) in comparison with other groups. A 2nd group of 80 patients (40%) have occasionally ventricular ectopic, their left ventricular end diastolic dimension is (52-58 mm) and ejection fraction in higher than the 3rd group 10 patients (5%) who had atrial fibrillation were having normal left ventricular end diastolic volume but ejection fraction was 45%. A 4th group of 40 patients (20%) were having occasional atrial ectopic have both normal ejection fraction and left ventricular end diastolic volume, the remaining 30 patients (15%) from the total did not develop any arrhythmia and their left ventricular end diastolic volume and ejection fraction were normal considered an control groups.
Conclusion: It was found that the development of arrhythmia is very significantly correlated with the abnormal increased left ventricular end diastolic volume and more lowering of ejection fraction.
The reaction oisolated and characterized by elemental analysis (C,H,N) , 1H-NMR, mass spectra and Fourier transform (Ft-IR). The reaction of the (L-AZD) with: [VO(II), Cr(III), Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II)], has been investigated and was isolated as tri nuclear cluster and characterized by: Ft-IR, U. v- Visible, electrical conductivity, magnetic susceptibilities at 25 Co, atomic absorption and molar ratio. Spectroscopic evidence showed that the binding of metal ions were through azide and carbonyl moieties resulting in a six- coordinating metal ions in [Cr (III), Mn (II), Co (II) and Ni (II)]. The Vo (II), Cu (II), Zn (II), Cd (II) and Hg (II) were coordinated through azide group only forming square pyramidal
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