To determine the relationship between celiac disease and reproductive complication, twenty five women with clinically definite unexplained infertility aged (22-35) have been investigated and compared to fifteen apparently healthy women. All the studied groups were subjected to measurement of anti-tissue transglutaminase antibodies IgA and IgG by ELISA technique and anti-endomysial antibodies IgA and IgG by IFAT technique .There was a highly significant elevation (P< 0.01) in the concentration of anti- tTG IgA Abs compared to control group, Also, there was significant elevation (P< 0.05) in the concentration of anti- tTG IgG Abs compared to control group .The results illustrated that the prevalence of anti-EMA IgA and IgG Abs were (5/25)20% and (3/25)12% respectively, and there was significant differences (P< 0.05) compared between studied groups. Frequency of HLA-DQ-8 by Real time PCR was (4/25)16% while no prevalence of HLA-DQ-2, and there was significant differences (P< 0.05) compared between studied groups. These results indicate that silent or sub- clinical celiac disease plays an important role in reproductive complication such as unexplained infertility.
To determine the relationship between celiac disease and reproductive disorder, twenty two women with recurrent spontaneous abortion (18-35) years have been investigated from the period 2017/11/1 – 2018/2/1 and compared wih twenty two parentally healthy women. All studied groups were carried out to measure antitissue transglutaminase IgA and IgG antibodies by Enzyme linked immunosorbent assay (ELISA) technique, There were a highly significant differences (P < 0.01) in the concentration of anti TtG IgA and IgG Ab compared to control group, while there was non-significant differences (P > 0.05) in the concentration of anti TtG IgA according to the age group and there was a significant difference (P < 0.05) in the concentration of anti TtG I
... Show MoreBackground:
the association between celiac disease and viral infection
To determine the relationship between chronic hepatitis B virus and autoimmune celiac disease, seventy five patients with chronic hepatitis B virus of ages (8-70) years have been investigated and compared with 50 healthy individuals. All the studied groups were carried out to measure antiGliadin antibodies IgA and IgG by ELISA test and anti-reticulin antibodies IgA and IgG by IFAT. There were significant elevation (P<0.05) in the concentration of AGA IgA and IgG antibodies compared to control group. The prevalence of AGA antibodies IgA and IgG was 8% and 9.33% respectively. There were a highly significant differences (P<0.01) between studies groups. The prevalence of antireticulin antibodies ARA IgA and IgG was 6.67% and 4.0% respectively i
... Show MoreInterleukin -33 is a new member of the IL-1 superfamily of cytokines that is expressed mainly by stromal cells.Its expression is upregulated following pro-inflammatory stimulation. Aim of the present study was to assess the serum IL-33 level and its relationship with inflammatory biomarker CRP in Iraqi females patients with celiac disease. Thirty five patients with celiac disease (CD) and thirty healthy individuals as control group were enrolled in this study,their age ranged (20-35) year.Anti-Gliadin IgA ,IgG and Anti-Tissue IgA ,IgG were estimated in all subjects as diagnostic parameters .ESR and CRP were assayed as inflammatory biomarkers. IL-33 was determined in patients and control groups.
... Show MoreInterleukin -33 is a new member of the IL-1 superfamily of cytokines that is expressed mainly by stromal cells.Its expression is upregulated following pro-inflammatory stimulation.Aim of the present study was to assess the serum IL-33 level and its relationship with inflammatory biomarker CRP in Iraqi females patients with celiac disease. Thirty five patients with celiac disease (CD) and thirty healthy individuals as control group were enrolled in this study,their age ranged (20-35) year.Anti-Gliadin IgA ,IgG and Anti-Tissue IgA ,IgG were estimated in all subjects as diagnostic parameters .ESR and CRP were assayed as inflammatory biomarkers. IL-33 was determined in patients and control groups.The results of the present study revealed a hig
... Show MoreThe relationship between infertility and Helicobacter pylori infection was investigated; samples from thirty-five infertile patients (aged 20-49 years) were collected from Kamal Al-Samaraei hospital , Baghdad, Iraq during the period from the first of February until April 2018. These patients were compared with 10 apparently fertile individuals who served as a control. The study was carried out to detect the DNA of H.pylori in both serum and seminal fluid of male infertile patients and for the control group by Real-Time Polymerase Chain Reaction (RT-PCR) technique. The results revealed that there was a significant difference (P<0.01) in the detection of DNA of H.pylori between pa
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Back ground: Inadequate secretory transformation of the endometrium resulting from deficient ovarian progesterone secretion is a cause of infertility and recurrent abortion
in luteal phase defects (LPD) women. LPD are diagnosed in 20% of infertile patients and 60% of patients with recurrent abortion and 50% of anovulatory women.
Aim : The objective of the present study was to compare pregnancy outcome following sperm penetration assay (SPA), intrauterine insemination (IUI) and luteal support
therapy (LST) in infertile patients with unexplained infertility (UI) mild and marked LPD.
Materials and Methods: Men with normal semen analyses and positive sperm penetration assay scores were included in this St
Back ground: Celiac disease (CD) is an immune–mediated enteropathy induced by gluten with broad spectrum of presentation, many patients with atypical symptoms or clinically silent remain undiagnosed, and are at risk of long-term complications.
Objective: The aim of the present study is to determine the of prevalence celiac disease in children with short stature.
Patient and Methods: In this prospective study, 307 children 181(58.9%)males and 126(41.1%) females ,with ages ranging from 3 to 17.5years ( mean 12.2 ±3.4) with short statures (height below 3rd percentile adjusted for age and sex) attending the consultation room of endocrinology/ Welfare Teaching Hospital/medical city- Baghdad , were enrolled in this study from the firs