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Publication Date

Fri Nov 24 2023

Journal Name

Iraqi Journal Of Science

Volume

55

Issue Number

3B

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كفاءة الهستخمص الزيتي لنبات الدارسين Cinnamomum zeylanicum عمى بعض الجوانب الفسمجية والنسجية في الفئ ا رن الهخهجة بالأكياس الهائية العذرية لمهشوكة الحبيبية Echinococcus granulosus

Cinnamomum zeylanicum

hydatid cysts

liver

spleen

red blood cell

شذى

امال

أريج

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هدٌفت الد ا رسة إل هعرفة تأثير الهستخمص الزيتي لىبات الدارسين

Cinnamomum zeylanicum عم بعض الجكاىب الفسمجية كالىس جية في الفئ ا رف الهخهجة بالأكياس العذرية أك الطكر اليرقي لمهشككة
الحبيبية Echinococcus granulosus .كتقيي كفاءة الهستخمص الزيتي لىبات الدارسيف ضد الإصابة
التجريبية بالأكياس الهائية العذرية. استخد 40 فأ ا ر قسهت إل أربع هجاهيع هتساكية .حقىت الفئ ا رف في
الهجكعة الأكل كالثاىية كالثالثة ب 2000 رؤيس أكلي / فأر ، فيها تركت الهجهكعة ال ا ربعة كهجهكعة سيطرة
سالبة )الهحقوىة بالهحموؿ الهمحي الطبيعي Normal saline . بعد أربعة أش رٍ هف الإصابة عكلجت الفئ ا رف
في الهجهكعة الثاىية كالثالثة بتركيز) 0.03 ك 0.04 همغ ( هف الهستخمص الزيتي لىبات الدارسيف عم التكالي هرة كاحد يكهيا لفترة أسبكعيف فيها تركت الهجهكعة الأكل كهجهكعة سيطرة هخهجة غير هعالجة
)سيطرة هكجبة (. درست التغي ا رت الهظ رٍية كالىسجية للأكياس الهائية العذرية كالأعضاءالهخهجة ب اٍ. كت
قياس بعض هعايير الد هى اٍ عدد كريات الد البيض WBC كالحهر RBC ك حجػػن كػريات الدن الهضغكط
PCV كىسبة خضاب الد Hb ، كها ت قياس الفعالية الإىزيهية لبعض إىزيهات الكبد هى اً ) GOT )
glutamate-oxaloacetate transaminase ك) GPT ) glutamate- pyruvate transaminase كها ت قياس هستكل السكر في هصؿ الد . أشارت اؿىتائج الأكلية في الفئ ا رف الهخهجة أف
الهستخمص الزيتي لىبات الد ا رسيف في التركيزييف كاف فعاؿ في إيقاؼ حيكية الرؤيسات الأكلية هقارىة بفئ ا رف
السيطرة الهكجبة. كها أكضحت الد ا رسة حدكث زيادة هعىكية ( P<0.05) في عدد كريات الد الحهر
كالحج الهرصكص لخلايا الد كىسبة خضاب الد في الفئ ا رف الهعالجة لاسيها تمؾ التي عكلجت بتركيز
0.04 همغ /هؿ هقارىة بهجهكعة السيطرة الهكجبة . كسجؿ اىخفاضا هعىكيا P<0.05) ( في عدد كريات
الد البيض في الفئ ا رف الهعالجة هقارىة بهجهكعة السيطرة الهكجبة . فضلا عف ذلؾ سجؿ اىخفاضا هعىكيا
(P<0.05) في الىشاط الإىزيهي لإىزي GOT ك GPT كزيادة هعىكية ( P<0.05) ؿهستكل السكر في
الد لؿفئ ا رف الهعالجة بهستخمص الدارسيف هقارىة بهجهكعة السيطرة الهكجبة . فيها أظ رٍت ىتائج الفحص
الىسيجي لمكبد كالطحاؿ حدكث ارتشاح كتىكس لمخلايا كاىعدا الىسؽ الخمكم لفئ ا رف السيطرة الهكجبة هقارىة
بالفئ ا رف الهعاهمة بهستخمص الدارسيف كبكلا التركيزيف . كعمي يهكف الاستىتاج بأف الهستخمص الزيتي لىبات
الد ا رسيف يحتكم عم هكاد فعالة ل اٍ كفاءة في القضاء عم الرؤيسات الأكلية داخؿ الجس الحي كها أف ل اٍ
القدرة عم تقميؿ بعض الإع ا رض الجاىبية التم يسبب اٍ ذٌا الطفيمي داخؿ الجس الحي. يؤهؿ أف يككف لىبات
الدارسيف أ هٌية في هعالجة داء الأكياس الهائية العذرية بديلان لمهعالجات الكيهيائية كالعهميات الج ا رحية.

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Publication Date

Tue Mar 15 2022

Journal Name

Journal Of Baghdad College Of Dentistry

In vitro cytotoxic effect of annona squamosa pulp ex-tract as a mouthwash for children on human normal cell line

Mosmann’s Tetrazolium Toxicity assay (MTT assay)

cytotoxicity

Annona squamosa

chlorhexidine

human dermal fibroblast of neonate (HDFn) cell line.

Sumaia Hussein

Zainab Juma

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Background: Fruits and their by-products are the primary sources of bioactive chemicals in plants. Because of its phytochemical richness, Annona squamosa fruits have gained the alertness of people willing in health-promoting diets. The purpose of this in vitro study was to evaluate the cytocompatibility effect of ethanolic crude extract of Annona squamosa pulp against a human normal cell line as a mouthwash for children. Material and method: The ethanolic extract of Annona squamosa pulp was extracted using the ultrasonic method and then lyophilized to make it powder. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide) test was performed to investigate the cytotoxic activity of the pulp extract on a human normal cell l

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Publication Date

Thu Jul 11 2024

Journal Name

Maaen Journal For Medical Sciences

Pharmacological Supplements Efficacy in Management of chronic pain associated with Sickle Cell Disease: A narrative review

Chronic pain

L-arginine

Nitric oxide

Omega 3

Opioid alternatives

SCD pain

Sickle cell anemia

Supplements

Vitamin D

Zinc

Ahmad

Samer Imad

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Sickle cell disease (SCD) is a hereditary ailment that can cause severe pain and suffering to people who are affected. However, with continued investment in research and treatment options, we can make progress towards improving the lives of those with SCD. Over 40% of patients experience painful vaso-occlusive crises (VOCs), so we must work towards finding solutions and providing support for those living with this condition, These episodes, a hallmark of SCD, significantly contribute to morbidity, mortality, and a diminished quality of life, while also incurring substantial healthcare costs. Chronic pain particularly affects older adolescents and adults with SCD, with over half reporting daily discomfort. Opioid-based analgesics, though sti

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Publication Date

Sun Dec 02 2012

Journal Name

Baghdad Science Journal

Synthesis, spectroscopic study of Pt (IV), Au (III), Rh(III),Co(II) and V (IV) complexes with sodium[5-(p-nitro phenyl) -/4- phenyl-1,2,4-triazole-3-dithiocarbamato hydrazide] and cytotoxicity assay on rhabdomyosarcoma cell line of heavy metals

" 5-(P-nitro phenyl)

-/4- phenyl-1

2

4-triazole

3-dithiocarbamato hydrazide

molar absorptivity

cytotoxic

RD cell line

exposure times

control positive."

Carolin. S.

Mahasin. F.

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All the prepared metal complexes of Pt (IV), Au(III), Rh (III), Co (II) and V(IV) with new ligand sodium [5-(p-nitro phenyl)-/4-phenyl-1,2,4-triazole-3-dithiocarbamato hydrazide] (TRZ.DTC) have been synthesized and characterized in solid state by using flame atomic absorption, elemental analysis C.H.N.S, FT-IR ,UV-Vis Spectroscopy, conductivity and magnetic susceptibility measurements. The nature of the complexes formed in ethanolic solution has been studied following the molar ratio method also was studied stability constant and found to be stable in molar ratio1:1 of VL (IV) and CoL(II) while Pt(IV), Au(III) and Rh(III) complexes stable in molar ratio 1:2 as well as the molar absorptivity for these complexes were calculated. From the prev

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Publication Date

Sun May 30 2021

Journal Name

Iraqi Journal Of Science

A correlation study between hyperthyroidism and some apoptosis markers among Iraqi patients

Hyperthyroidism

Antibody-Thyroid Stimulating Hormone Receptor

Apoptosis

Tumor Necrosis Factor-Alpha

Tumor Protein 53

B-cell Lymphoma 2

Factor Related Apoptosis Ligand

Zainab A.

Shaima R.

Aida H.

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This study was carried out in the Center of Endocrinology and Diabetes in Baghdad during the period between October 2019 to February 2020. The aim was to measure the level of some apoptosis markers and some autoimmune antibodies related to the thyroid gland in Iraqi patients with hyperthyroidism and evaluate the correlation between all the measured parameters. The study included 88 patients who were divided into three groups; group 1 included 30 newly diagnosed hyperthyroidism patients (24 females, 6 males); group 2 included 30 patients of hyperthyroidism who were under treatment (28, 2 males); group 3 included 28 healthy individuals as control group (22 females, 6 males).

Most of the patient's ages

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Publication Date

Sun Oct 01 2006

Journal Name

Journal Of The Faculty Of Medicine Baghdad

Alcoholic Liver Disease: Alfa Fetoprotein Alteration, Hematological & Biochemical Characteristics

Alcoholic liver disease

Alfa fetoprotein

gamma glutamyl transpeptidase. Statistical analysis: Chi square tests and the mean value with SD for each value were determined using ANOVA. A p value of <0.05 was considered to be positive.

Aswad

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Background: Alcohol remains the single most significant cause of liver disease throughout the Western world, responsible for between 40 and 80% of cases of cirrhosis in different countries. Many of the factors underlying the development of alcoholic liver injury remain unknown, and significant questions remain about the value of even very basic therapeutic strategies.
Patients and Methods: In a cross sectional study, 113 alcoholic patients with evidence of liver disease in the absence of other significant etiology attending the Gastoenterorology and Hepatology Teaching Hospital between December 2001 and December 2003 were studied for the hematological and biochemical spectrum of alcoholic liver disease in

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Publication Date

Mon Apr 06 2020

Journal Name

August

INFLUENCE OF SOME FACTOR ON SOMATIC EMBRYOS INDUCTION AND GERMINATION OF DATE PALM CV BARHI BY USING CELL SUSPENSION CULTURE TECHNIQUE

This study was done to examine different concentrations of mercuric chloride (Hgcl2) for Explants sterilization and different concentration of NAA) mg/L with 2iP for their effect on initiation primary callus and subsequent embryogenesis in Phoenix dactyliferae cultivar Barhi. Leaf primordial and shoot tips were excised from 2-3 years old offshoot. The result showed that contamination percentage decreased with an increase in concentration of Hgcl2 for two explants where in the control (0.0)% gave highest value 75% and 62.5% of contamination for leaf primordial and shoot tip respectively while the addition (0.1)% gave a significant decrease 37.5 and 0% for explants respectively. The Explants were inoculated onto Murashiege and Skoog

1962 (MS) medium supplemented with 2iP 3mg/L and containing 0

25

50 or 100 mg/L of NAA

the addition (50) mg/L of NAA gave highest value 68.8% in percentage of callus initiation with significant difference from addition 0% gave lowest value (18.8)%

as well Explants of shoot tip gave significant difference was 53.1% while leaf primordial gave 28.1%

Primary callus was transferred to fresh MS medium containing (0

5

10 and 20) mg/L of NAA with 3mg/L 2iP

Results were recorded after 12 weeks. A highest value of embryonic callus induction percentage or fresh weight and dry weight 87.5% or 1.56g and 0.47g for the character respectively for the treat 20 mg/L while control treatment 0.0 gave the lowest value 12.5% or 0.37g and 0.14g for same character respectively. Inoculated 1g fresh biomass into a 250 ml Erlenmeyer flask containing 50 ml MS liquid medium supplemented with NAA 20mg/L and agitated at 150 rpm by shaker to making suspension culture the measurements of packed cell volume ( pcv) or fresh and dry weight taken weekly for 12 weeks

maximum values were reached in the eighth week of PCV and fresh weight but the dry weight reached to highest value in seventh week

then the curve began to decline gradually until it reached stability in the last two weeks. The cell suspension was Diluted to different initial cell density of 100

500

10000

50000 and 100000 cells /ml with hemocytometer. The initial cell number of (10000) cells gave significant different of plating efficiency PE (11.6)% while (100) cells gave lowest value 1.8% of PE.

Ali A.

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Publication Date

Fri Jul 29 2022

Journal Name

Journal For Vascular Ultrasound

A Comparative Study of the Right and Left Carotid Arteries in Relation to Age for Patients With Diabetes and Hypertension

Introduction: Age

hypertension

and diabetes can cause significant alterations in arterial structure and function

including changes in lumen diameter (LD)

intimal-medial thickness (IMT)

flow velocities

and arterial compliance. These are also considered risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and IMT has been reported by some researchers

and a difference in the incidence of nonlacunar stroke has been reported between the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and left common carotid arteries and internal carotid arteries in patients with hypertension and diabetes for 2 age groups. Methods: We studied 250 patients with both diabetes and hypertension. Patients were divided into 2 age groups with the old age group being 56 to 75 years and the young age group 35 to 55 years. The bilateral common carotid and internal carotid arteries were evaluated with B-mode ultrasound and Doppler examinations. The LD and IMT were measured for both common carotid arteries

and spectral waveform parameters and indices were recorded for both internal carotid arteries. Results: The difference in LD between the left and right common carotid arteries for the old age group was 11.64% and for the young age group was 6.42%

with significant P values of <.05 for both age groups. The difference in IMT between the left and right common carotid arteries was 18.27% in the old age group compared with 15.38% in the young age group

with significant P values of <.05. There was a difference in peak systolic velocity between the left and right internal carotid arteries of 4.85% in the old age group which was not significant

compared with 14.28% in the young age group with a significant P value <.05

whereas the difference in end-diastolic velocity between the left and right internal carotid arteries was not significant for both age groups. Differences between the right and left internal carotid arteries for resistive index

pulsatility index

and pressure gradient were significant only in the young age group. Conclusion: We found significant differences between the right and left common carotid and internal carotid arteries in patients with diabetes and hypertension which were more prominent in the young age group. Values for common carotid IMT and LD were significantly higher in the left common carotid artery versus the right common carotid artery in both age groups. Differences between the 2 carotid sides may be attributed to anatomic variations in the common carotid artery origins which lead to differences in stress between the 2 sides

Ahmed Abduljabar

Samar I.

Anmar Z

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Introduction:

Age, hypertension, and diabetes can cause significant alterations in arterial structure and function, including changes in lumen diameter (LD), intimal-medial thickness (IMT), flow velocities, and arterial compliance. These are also considered risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and IMT has been reported by some researchers, and a difference in the incidence of nonlacunar stroke has been reported between the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and left common carotid arteries and internal carotid arteries in patient

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