Preferred Language
Articles
/
bsj-2139
IL-17 in Protective Immunity to Vaginal Candidiasis
...Show More Authors

Vulvovaginal candidiasis (VVC) is caused by Candida albicans affects a significant number of women during their reproductive ages. Th17 cells play a major role in coordinating the host defense in oropharyngeal candidiasis. In this study we investigated the involvement of the Th17 response in an animal model of vulvovaginal candidiasis (VVC). The present study aimed to shed light on detect concentration of the IL-17 of infected animal and control . A direct Enzyme Linked Immunosorbent Assay (ELISA) was used to quantify IL-17 concentrations in 30 infected animal with VVC and 10 control group. Rats were intravaginally inoculated with C.albicans, and vaginal lavage fluids, serum were evaluated for proinflammatory cytokine IL-17 The data suggest that IL-17, produced by vaginal cells, particularly CD4 T cells, detected in the vaginal wash and serum during the infection, reaching a maximum 14 days after the challenge.

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Sun Jan 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Serum IL-17 and postmenopausal osteoporosis
...Show More Authors

Background: Osteoporosis is a bone condition that makes bones thininer and more fragile because of reduced bone density and it puts people at risk of fractures, especially of the hip, spinal vertebrae and wrist.
Objective: This study will highlighted the role of IL-17 in postmenopausal osteoporosis.
Patients and methods: This study applied on 84 includes subjects (42 postmenopausal osteoporosis patient and 42 of healthy control group), conducted from December 2014 to March 2015 to measure the IL-17 serum level by using ELISA kit.
Results: In osteoporotic postmenopausal women the mean of serum IL-17 was (0.49pg/ml) and it is significantly higher than that of healthy group (0.09pg/ml).
Conclusion: Serum IL-17 was significantly

... Show More
View Publication Preview PDF
Crossref
Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
Some Immunological Parameters Paraw in Women with vaginal candidiasis
...Show More Authors

This study was conducted to know some Immune responses in women with vaginal candidias is by Candidia species. Hemoglubin (Hb) was decreased significantly in patient women comparing with control group. The differential count of Blood cells revealed that neutrophils and monocytcs were increased significantly in patient women comparing with control group. The percentage of the Phagocytosis index was decreased significantly in patient women (66.45 + 15.05) comparing with control group (73.72 + 3.77) and the T- lymphocytes were decreased also in patient women (57.75 + 18.787) comparing with control group (74.25 + 7.759).

View Publication Preview PDF
Publication Date
Tue Jan 02 2018
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Epidemiology of vaginal candidiasis among pregnant women attending Tikrit teaching hospital/Iraq.
...Show More Authors

Back ground: Vaginal candidiasis is the second common infection among child bearing women. The disease is caused by yeast organism especially Candida albican. Pregnancy is one of the risk factors of the disease. It has been revealed that more than 75 % of women may experience an attach of the disease during their life time.
Objectives: To study the epidemiological factors of vaginal candidiasis among pregnant women attending Tikrit teaching hospital out-patient clinic.
Patients and methods: The study was conducted on a sample of (120) pregnant women. The demographic and epidemiologic information was obtained according to special designed questionnaire. The study was done over a period from 1/3/2017 to 16/4/2017. Vaginal swabs were

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Sun Jul 02 2017
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Crude Anthrax Protective Antigen Enhances Immunity For Salmonella Typhimurium in Mice
...Show More Authors

Background:Non-host-adapted Salmonella serovar Typhimurium is a facultative intracellular bacterium, which invades and multiplies within mononuclear phagocytes in liver, spleen, lymph nodes and Peyer’s plaques. Salmonella infection is a crucial medical and veterinary problem globally. S. Typhimurium causes various clinical symptoms, from asymptomatic infection to typhoid-like syndromes in infants or highly susceptible animals, for instance mice.
Objective: The present study was carried out to investigate the efficacy of anthrax protective antigen (PA)as a potent adjuvant mixed with killed Salmonella Typhimurium (S.T.) to enhance the immunization capacity of the last.
Materials and Methods: Two groups of mice were immunized with e

... Show More
View Publication Preview PDF
Crossref
Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
Study a bout the Epidemiology of Vulvo Vaginal Candidiasis (Candida spp.) in Baghdad City
...Show More Authors

This Study was conducted to investigate vaginitis in women who live in Baghdad City. Results Revealed that Candida spp. were the causal agent of 38.5% of symptomatic cases the yeasts Candidaalbicans, C.glabrata, C.tropicalis, C.parapsilosis and C.krusei were isolated with the percentage of 38.1, 9.1, 3.9, 2.6, 1.3 respectively also there were 18% of women in control group carrying Candida spp. The direct smear method were not efficient because the percentage of infection was 17.5% comparing with the culture method the sensitivity of direct smear method was 45.5% The percentage of WBC to Epithelial cells was less than one in 76.6% of women.

View Publication Preview PDF
Publication Date
Sat Jun 24 2017
Journal Name
Fac Med Baghdad
Crude Anthrax Protective Antigen Enhances Immunity For Salmonella Typhimurium in Mice
...Show More Authors

Background: Non-host-adapted Salmonella serovar Typhimurium is a facultative intracellular bacterium, which invades and multiplies within mononuclear phagocytes in liver, spleen, lymph nodes and Peyer’s plaques. Salmonella infection is a crucial medical and veterinary problem globally. S. Typhimurium causes various clinical symptoms, from asymptomatic infection to typhoid-like syndromes in infants or highly susceptible animals, for instance mice. Objective: The present study was carried out to investigate the efficacy of anthrax protective antigen (PA)as a potent adjuvant mixed with killed Salmonella Typhimurium (S.T.) to enhance the immunization capacity of the last. Materials and Methods: Two groups of mice were immunized with either th

... Show More
Preview PDF
Publication Date
Thu Jun 30 2011
Journal Name
Al-kindy College Medical Journal
Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
...Show More Authors

Background: Salvia officinalis is a plant belong to
Labiatae family .The common name of Salvia is sage
which mean save. The leaves of Salvia have special
oil which is effective against filamentous fungi and
yeasts such as Candida albicans which is the
causative agent of vaginal candidiasis in women
Methods. Cultures from 50 swabs of Candida
albicans isolated from vagina of 70 patient women
who complains from vaginal problems, their ages
(24-43) years from Central City Hospital during
Febreoury 2009 to April 2009 were cultured on
Sabouraud Dextrose Agar (SDA) .Nystatin was used
as positive reference standard to determine the
sensitivity of this fungus . and less this concentration
there was no min

... Show More
View Publication Preview PDF
Publication Date
Thu Sep 30 2021
Journal Name
Iraqi Journal Of Science
Detection of Serum Levels of IL-17 and CCL-5 in a Sample of Iraqi Pulmonary Tuberculosis Patients
...Show More Authors

      Cytokines and chemokines are small-secreted proteins involved in many aspects of cell development, differentiation, and activation functions. A prominent characteristic of these molecules is their effect on the immune system in relation to the development of cell trafficking and immune tissues and organs. Furthermore, they play an important role in initiating and coordinating the organized and sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected lungs. We aimed to evaluate the levels of interleukin -17 (IL-17) and the chemotactic chemokine (C-C motif) ligand 5 (CCL5) in the sera of pulmonary tuberculosis (PTB) patients. About 90 subjects were included, involving 5

... Show More
View Publication Preview PDF
Scopus (3)
Crossref (1)
Scopus Crossref
Publication Date
Fri May 12 2023
Journal Name
European Journal Of Dentistry
Salivary IL-17 and IL-10 as Potential Diagnostic Biomarkers of Different Stages of Periodontitis in Smoker and Nonsmoker Patients
...Show More Authors
Abstract<p> Objectives The gold standard in the field of periodontal research currently is to find a valid biomarker that can reliably be used for diagnosing periodontal diseases. Given the limitations of the current diagnostic tools that stall to predict susceptible individuals and determine whether active tissue destruction is occurring, there is an increased urge to develop alternative diagnostic techniques that would compensate for the problems inherited in these available methods, such as measuring levels of biomarkers present in oral fluids such as saliva; so the aim of this study was to determine the diagnostic potential of interleukin-17 (IL-17) and IL-10 to differentiate periodontal health </p> ... Show More
View Publication
Scopus (2)
Crossref (3)
Scopus Clarivate Crossref
Publication Date
Fri Mar 27 2020
Journal Name
Iraqi Journal Of Science
A Study of the Association Between IL-17 and HOMA-IR in Iraqi Type 2 Diabetic Patients
...Show More Authors

Type 2 Diabetes Mellitus (T2DM) is the furthermost common form of DM which is identified by hyperglycemia, insulin resistance, and relative insulin deficiency. This study aims to detect the role of interleukin-17 (IL-17) in patients with T2DM compared with the healthy control and to investigate the relationship between IL-17 and insulin resistance. The study involved 50 Iraqi T2DM patients, randomly selected with an age range of 33-71 years .For the purpose of comparison, 30 Iraqi healthy persons with an age range of 33-71 years were also included. Patients and control groups were characterized in terms of gender, age, body mass index (BMI), homeostatic model assessment-insulin resistance(HOMA-IR),fasting serum glucose (FSG) and lipid pr

... Show More
View Publication Preview PDF
Scopus (9)
Crossref (2)
Scopus Crossref