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Phytochemical Investigation of Alkaloids in the Iraqi Echinops heterophyllus (Compositae)
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Alkaloids are a group of naturally occurring chemical compounds that contain mostly basic nitrogen atoms . They are a large family of compounds synthesized by plants in addition to the bacteria, fungi, and animals,  they often have pharmacological effects. The aim of this study is to isolate and identified alkaloids in a newly studied, wild Iraqi plant named Echinops heterophyllus. The medicinal importance of alkaloids, on one hand  and the absence of any phytochemical investigation on heterophyllus species of echinops genus on the other hand , acquired this study its importance. Three alkaloids (named E1, E2 and E3) were isolated from seed plant part by two chromatographic methods: Preparative high Performance Liquid Chromatography (PHPLC) and preparative thin layer chromatography (PTLC), one of them identified as(1-Methyl-2,3-dihydro-4(1H)-quinolinone by different chemical analysis like: ultra violet spectrum analysis (UV spectrum), Fourier transforms infrared spectra (FT-IR) , elemental microanalysis (CHN) and Proton1H-NMR and carbon 13C-NMR analysis.

Key words: Echinops, heterophyllus, quinoline alkaloids.

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Publication Date
Wed Feb 08 2023
Journal Name
Iraqi Journal Of Science
Palynological Study for the Species of the Genus Echinops L. (compositae) in Iraq
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The paper comprise comparative palynological study of (11) species belong to the genus Echinops L. in Iraq i.e( E.armatus Boiss. & Hausskn ، E.bicolor Nabelek. ، E.cephalotes DC., E.haussknetchii Boiss. ، E.mosulensis ، Rech. ،
E.nitens Bornm. ، E.orientalis Trautv., E.parviflorous BOISS & BUHSE ،
E.spinossisms Turra . ، E.tenuisectus Rech. ، E.viscosus DC.، Pollen grain were found to be Tricolporate and with spherical shaped ,in polar view the grain found to be Interangular , while in equatorial view the grain found to be ellipsoid .

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Hepatoprotective Effect of Echinops tenuisectus (Compositae) on CCl4 Induced Hepatic Damage in Rats
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Flavonoids are known to play a vital role in the management of various liver disorders.They are a large family of compounds synthesized by plants; they belong to a group of natural substances with variable phenolic structures. In this study we aim to scan the types of flavonoids in a newly studied, wild Iraqi plant named Echinops tenuisectus of Compositae family. The medicinal importance of flavonoids on one hand, and the absence of any phytochemical investigation on tenuisectus species of Echinops genus on the other hand, acquired this study itÛ¥s importance. Three flavonoids were identified in the seed,s extract of this plant (Silymarin, Rutin, Quercetin ) by two chromatographic methods, first Thin laye

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Publication Date
Wed Feb 08 2023
Journal Name
Iraqi Journal Of Science
Ecology and Geographical Distribution for Six Species of the Genus Echinops L.(compositae) in Iraq
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This study includes six species related to the genus Echinops L. (composite) grown in Iraq which are listed below: E.armatus Boiss. & Hausskn., E. bicolor Nabelek, E. cephalotes DC., E.haussknechtii Boiss., E. moulensis Rech., E. nitens Bornm., the geographical distribution and ecological preferences' were documented.
It has been also observed that this genus was distributed near waterfalls, vallies, road side, dry limestone, clay soil and hard rocky soil in Different heights. The most separated species was E.armatus and the least separated one was E.haussknechtii, the species was listed in diagram and distributed on a map.

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Publication Date
Sun Dec 27 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Phytochemical Investigation of the Aerial Part of Iraqi Convolvulus arvensis
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Convolvulus arvensis is a species of bindweed that is rhizomatous and is in the morning glory family (Convolvulaceae) native to Europe and Asia. The plant is naturally grown in Iraq. The plant was reported to be used in traditional medicine from as early as 1730s.

The Aerial parts of Convolvulus arvensis were macerated in 80% ethanol for 6 days. The concentrated extract was partitioned with n-hexane, chloroform, ethyl acetate- and n-butanol successively. The n-hexane and ethyl acetate, fractions were examined for the presence of phytochemicals by thin l

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Publication Date
Sun Dec 27 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Phytochemical Investigation of Aerial Parts of Iraqi Cardaria draba
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 The aim of this study was to study chemical constituents of aerial parts of Cardaria draba since no phytochemical investigation had been studied before in Iraq. Aerial parts of Cardaria draba were defatted by maceration in hexane for 72 h. The defatted plant materials were extracted using Soxhlet apparatus, the aqueous Methanol 90% as a solvent extraction for 18 h, and fractionated with petroleum ether- chloroform (CHCl3)- ethylacetate- and n-butanol respectivly. The ethyl acetate, n-butanol, and n-butanol after hydrolysis fractions were investigated by high performance liquid chromatography (HPLC) and thin-layer chromatography (TLC) for its phenolic acid and flavonoid contents. Flavono

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Publication Date
Mon Mar 27 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Phytochemical Investigation and Antioxidant Activity of Iraqi Tribulus terrestris
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The aim of the present study was to characterize the Iraqi Tribulus terrestris for the presence of biologically active phyto-chemicals using methanolic extracts of the plant (aerial parts) by Gas Chromatography –Mass spectrometry (GC/MS), while the mass spectra of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST) library , in addition to study the antioxidant activity of plant extract , results confirmed the presence of therapeutically potent compounds in the Iraqi Tribulus terrestris extract predominantly alkaloids, flavonoids, saponins, tannins and terpenoids. Antioxidant potential of Iraqi Tribulus terrestris

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Publication Date
Thu Jun 23 2022
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Phytochemical screening and Free radicals scavenging activity of leaves of Echinops polyceras Boiss. grown in Syria
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Free radicals are reactive compounds, their excessive production is considered to be an important cause of oxidative damage in biomolecules causing degenerative diseases. Polyphenols are one of the most important groups of secondary metabolites of plants, which have an antioxidant activity depending on their properties as hydrogen donors. Echinops polyceras Boiss. (Asteraceae) is one of Echinops genus species that spread in Syria, Lebanon, and Palestine. Phytochemicals found in this species leaves have been extracted with gradient polarity solvents, and primary screening of the secondary metabolites was established. The phenolic compounds and flavonoids contents were determined. The free radicals scavenging activity was evaluated for all

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Publication Date
Sat Sep 25 2021
Journal Name
International Journal Of Drug Delivery Technology
Phytochemical investigation of some active components in Iraqi conyza canadensis (Syn. erigeron canadensis)
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This study aimed to explore and separate the phytochemicals of the whole plant Conyza canadensis, a naturally growing plant in Iraq, since no phytochemical research was done previously in Iraq. The whole plant of C. canadensis was defatted by maceration in hexane for 24 hours. The defatted plant materials were extracted using Soxhlet apparatus, the aqueous ethanol 85% as a solvent extraction for 9 hours, and fractionated by petroleum ether, chloroform, ethyl acetate, and n-butanol. The petroleum ether, chloroform, and ethyl acetate fractions were analyzed by high-performance liquid chromatography (HPLC) for their steroids, alkaloids, and polyphenolic (phenolic acids and flavonoids) contents. One alkaloid was isolated from chloroform fractio

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Publication Date
Wed May 24 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Investigation of alkaloids of Anabasis aphylla (Chenopodiaceae)
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The aerial part of Iraqi Anabasis aphylla (Chenopodiaceae) had been investigated for its alkaloidal contents.The alkaloid anabasine [2-(3-pyridyl)-piperidine] [1] & aphyllidine were isolated from an ethanolic extract of the plant. Isolation of the alkaloid was done by column chromatography followed by preperative thin layer chromatography. Identification of the isolated alkaloid was done by different spectroscopic methods (UV,IR), refractive index & TLC using authentic sample & preparation of a salt.

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Publication Date
Sun Dec 27 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Phytochemical Investigation and Anti-angiogenic Examination of Iraqi Vigna radiata L. Seeds and Sprouts
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Abstract

  The objective of this study was to investigate the phytochemical constituents of two different parts of Vigna radiata (seeds and sprouts), and identify their  anti angiogenic activity .the goal was achieved by Preliminary qualitative phytochemical screening for crude ethanolic extract of two parts of plant

 ; rat aorta anti-angiogenesis assay had been conducted for both extracts .   isolation , separation and purification of some phytochemical constituents that belong to important groups (flavonoids) from  n-butanol fraction extract of Vigna radiata plant had been done in pure form by using preparative thin layer chromatography ( PTLC ) and then

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