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bijps-1747
Impact of omega 3 alone or in combination with irinotecan on bone marrow and spleen of rats: in vivo study
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Abstract

Objectives: The present study designed to explore the genotoxicity through measurement of Mitotic index in bone marrow and the spleen cells, as possible mechanism of bone marrow and spleen toxicity that induced by irinotecan; and to describe the protective actions of omega 3 against irinotecan induced genotoxicity in bone marrow and the spleen of rats.

Methods: Twenty four (24) rats (Sprague-Dawley) were randomly divided into four groups: Group Ӏ, rats  received single oral daily dose of distilled water (2 ml/kg) for 25 days (negative control group); Group ӀӀ (irinotecan-treated), received single daily oral dose of (2 ml/kg) distilled water for 25 days by the oral gavage and subsequently received irinotecan (50mg/kg) on days: 5, 10, 15 (total dose=150 mg/kg) by intraperitoneal injection; Group ӀӀӀ, received oral dose of Omega-3 fish oil (600mg/kg/day) daily for 25 successive days by oral gavage (Omega-3 fish oil-treated); Group ӀV (Omega-3 fish oil + irinotecan), received oral dose of Omega-3 fish oil (600mg/ kg/ day) given daily for 25 successive days by oral gavage, and received subsequently irinotecan (50mg / kg body weight) on days: 5, 10, 15 (total dose=150 mg/kg) by intraperitoneal injection.

Results: Mitotic index in the Bone Marrow and in the Spleen Cells were shown to be significantly decreased (p<0.05) in rats treated with irinotecan (group ІІ) compared to corresponding levels in the negative control group (Group I) of the rats; Orally administered Omega-3 fish oil with total cumulative dose of irinotecan (Group IV), resulted in significant elevation (P<0.05) of the Mitotic index in bone marrow and the spleen cells compared to corresponding levels in rats treated with irinotecan (group ІІ).

Conclusion: Results of current study suggested that the administration of Omega-3 fish oil could be useful supplements that may alleviate irinotecan induced genotoxicity through the elevation of mitotic indices in bone marrow and the spleen cells of the rats; but, in mild level.

 

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Publication Date
Tue Sep 01 2015
Journal Name
Journal Of Al-nahrain University-science
St-closed Submodule
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Abstract Throughout this paper R represents commutative ring with identity and M is a unitary left R-module, the purpose of this paper is to study a new concept, (up to our knowledge), named St-closed submodules. It is stronger than the concept of closed submodules, where a submodule N of an R-module M is called St-closed (briefly N ≤Stc M) in M, if it has no proper semi-essential extensions in M, i.e if there exists a submodule K of M such that N is a semi-essential submodule of K then N = K. An ideal I of R is called St-closed if I is an St-closed R-submodule. Various properties of St-closed submodules are considered.

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Publication Date
Thu May 28 2020
Journal Name
Iraqi Journal Of Science
Synthetic Aperture Radar Image Classification: a Survey: Survey
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In this review paper, several studies and researches were surveyed for assisting future researchers to identify available techniques in the field of classification of Synthetic Aperture Radar (SAR) images. SAR images are becoming increasingly important in a variety of remote sensing applications due to the ability of SAR sensors to operate in all types of weather conditions, including day and night remote sensing for long ranges and coverage areas. Its properties of vast planning, search, rescue, mine detection, and target identification make it very attractive for surveillance and observation missions of Earth resources.  With the increasing popularity and availability of these images, the need for machines has emerged to enhance t

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Publication Date
Sun Jun 06 2010
Journal Name
Baghdad Science Journal
Stochastic Non-Linear Pseudo-Random Sequence Generator
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Many of the key stream generators which are used in practice are LFSR-based in the sense that they produce the key stream according to a rule y = C(L(x)), where L(x) denotes an internal linear bit stream, produced by small number of parallel linear feedback shift registers (LFSRs), and C denotes some nonlinear compression function. In this paper we combine between the output sequences from the linear feedback shift registers with the sequences out from non linear key generator to get the final very strong key sequence

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Publication Date
Sun Jun 07 2009
Journal Name
Baghdad Science Journal
Limits between the Cosmological Parameters from Strong Lensing Observations for Generalized Isothermal Models
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This paper including a gravitational lens time delays study for a general family of lensing potentials, the popular singular isothermal elliptical potential (SIEP), and singular isothermal elliptical density distribution (SIED) but allows general angular structure. At first section there is an introduction for the selected observations from the gravitationally lensed systems. Then section two shows that the time delays for singular isothermal elliptical potential (SIEP) and singular isothermal elliptical density distributions (SIED) have a remarkably simple and elegant form, and that the result for Hubble constant estimations actually holds for a general family of potentials by combining the analytic results with data for the time dela

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Publication Date
Fri Jan 01 2016
Journal Name
Bulletin Of Mathematics And Statistics Research
New Approximation Operators Using Mixed Degree Systems
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This paper is concerned with introducing and studying the first new approximation operators using mixed degree system and second new approximation operators using mixed degree system which are the core concept in this paper. In addition, the approximations of graphs using the operators first lower and first upper are accurate then the approximations obtained by using the operators second lower and second upper sincefirst accuracy less then second accuracy. For this reason, we study in detail the properties of second lower and second upper in this paper. Furthermore, we summarize the results for the properties of approximation operators second lower and second upper when the graph G is arbitrary, serial 1, serial 2, reflexive, symmetric, tra

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Publication Date
Wed Feb 01 2017
Journal Name
International Journal Of Science And Research (ijsr)
Fibrewise Bitopological Spaces
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We introduce and discus recent type of fibrewise topological spaces, namely fibrewise bitopological spaces, Also, we introduce the concepts of fibrewise closed bitopological spaces, fibrewise open bitopological spaces, fibrewise locally sliceable bitopological spaces and fibrewise locally sectionable bitopological spaces. Furthermore, we state and prove several propositions concerning with these concepts.

Publication Date
Sat Jan 01 2022
Journal Name
Turkish Journal Of Physiotherapy And Rehabilitation
classification coco dataset using machine learning algorithms
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In this paper, we used four classification methods to classify objects and compareamong these methods, these are K Nearest Neighbor's (KNN), Stochastic Gradient Descentlearning (SGD), Logistic Regression Algorithm(LR), and Multi-Layer Perceptron (MLP). Weused MCOCO dataset for classification and detection the objects, these dataset image wererandomly divided into training and testing datasets at a ratio of 7:3, respectively. In randomlyselect training and testing dataset images, converted the color images to the gray level, thenenhancement these gray images using the histogram equalization method, resize (20 x 20) fordataset image. Principal component analysis (PCA) was used for feature extraction, andfinally apply four classification metho

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Publication Date
Sun Aug 01 2021
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Fibrewise Fuzzy Topological Spaces
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     We introduce and discuss the modern type of fibrewise topological spaces, namely fibrewise fuzzy topological spaces. Also, we introduce the concepts of fibrewise closed fuzzy topological spaces, fibrewise open fuzzy topological spaces, fibrewise locally sliceable fuzzy topological spaces and fibrewise locally sectionable fuzzy topological spaces. Furthermore, we state and prove several theorems concerning these concepts.

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Publication Date
Fri Jan 20 2023
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Ϣ-Semi-p Open Set :
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Csaszar introduced the concept of generalized topological space and a new open set in a generalized topological space called -preopen in 2002 and 2005, respectively. Definitions of -preinterior and -preclosuer were given. Successively, several studies have appeared to give many generalizations for an open set. The object of our paper is to give a new type of generalization of an open set in a generalized topological space called -semi-p-open set. We present the definition of this set with its equivalent. We give definitions of -semi-p-interior and -semi-p-closure of a set and discuss their properties. Also the properties of -preinterior and -preclosuer are discussed. In addition, we give a new type of continuous function

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Publication Date
Wed May 03 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Strongly (Completely) Hollow Sub-modules II
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  Let M be an R-module, where R is commutative ring with unity. In this paper we study the behavior of strongly hollow and quasi hollow submodule in the class of strongly comultiplication modules. Beside this we give the relationships between strongly hollow and quasi hollow submodules with V-coprime, coprime, bi-hollow submodules.

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