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Impact of omega 3 alone or in combination with irinotecan on bone marrow and spleen of rats: in vivo study
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Abstract

Objectives: The present study designed to explore the genotoxicity through measurement of Mitotic index in bone marrow and the spleen cells, as possible mechanism of bone marrow and spleen toxicity that induced by irinotecan; and to describe the protective actions of omega 3 against irinotecan induced genotoxicity in bone marrow and the spleen of rats.

Methods: Twenty four (24) rats (Sprague-Dawley) were randomly divided into four groups: Group Ӏ, rats  received single oral daily dose of distilled water (2 ml/kg) for 25 days (negative control group); Group ӀӀ (irinotecan-treated), received single daily oral dose of (2 ml/kg) distilled water for 25 days by the oral gavage and subsequently received irinotecan (50mg/kg) on days: 5, 10, 15 (total dose=150 mg/kg) by intraperitoneal injection; Group ӀӀӀ, received oral dose of Omega-3 fish oil (600mg/kg/day) daily for 25 successive days by oral gavage (Omega-3 fish oil-treated); Group ӀV (Omega-3 fish oil + irinotecan), received oral dose of Omega-3 fish oil (600mg/ kg/ day) given daily for 25 successive days by oral gavage, and received subsequently irinotecan (50mg / kg body weight) on days: 5, 10, 15 (total dose=150 mg/kg) by intraperitoneal injection.

Results: Mitotic index in the Bone Marrow and in the Spleen Cells were shown to be significantly decreased (p<0.05) in rats treated with irinotecan (group ІІ) compared to corresponding levels in the negative control group (Group I) of the rats; Orally administered Omega-3 fish oil with total cumulative dose of irinotecan (Group IV), resulted in significant elevation (P<0.05) of the Mitotic index in bone marrow and the spleen cells compared to corresponding levels in rats treated with irinotecan (group ІІ).

Conclusion: Results of current study suggested that the administration of Omega-3 fish oil could be useful supplements that may alleviate irinotecan induced genotoxicity through the elevation of mitotic indices in bone marrow and the spleen cells of the rats; but, in mild level.

 

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Publication Date
Wed Oct 01 2014
Journal Name
International Journal Of Emerging Technology And Advanced Engineering
Natural Yellow3 for Dye Sensitized Solar Cell
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Abstract: The natural dye, Curcumin, was extracted from Curcuma longa using as a sensitizer in two types of dye sensitized solar cell (DSSC), and their characteristics were studied. The absorption spectrum of the dye solutions, as well as the wavelength of the maximum absorbance of the dye loaded TiO2 film has been studied. The X-Ray diffraction pattern of TiO2 film made with Doctor-Blading technique shown that the grain size of TiO2 was equal to be 40 nm. The electrical performances in terms of short circuit current, open circuit voltage and power conversion efficiency of cells were investigated.

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Publication Date
Mon Dec 25 2017
Journal Name
Al-khwarizmi Engineering Journal
A new Cumulative Damage Model for Fatigue Life Prediction under Shot Peening Treatment
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In this paper, fatigue damage accumulation were studied using many methods i.e.Corton-Dalon (CD),Corton-Dalon-Marsh(CDM), new non-linear model and experimental method. The prediction of fatigue lifetimes based on the two classical methods, Corton-Dalon (CD)andCorton-Dalon-Marsh (CDM), are uneconomic and non-conservative respectively. However satisfactory predictions were obtained by applying the proposed non-linear model (present model) for medium carbon steel compared with experimental work. Many shortcomings of the two classical methods are related to their inability to take into account the surface treatment effect as shot peening. It is clear that the new model shows that a much better and cons

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Publication Date
Thu Mar 18 2010
Journal Name
Spe Projects, Facilities & Construction
Correlating Optimum Stage Pressure for Sequential Separator Systems
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Summary<p>A study to find the optimum separators pressures of separation stations has been performed. Stage separation of oil and gas is accomplished with a series of separators operating at sequentially reduced pressures. Liquid is discharged from a higher-pressure separator into the lower-pressure separator. The set of working separator pressures that yields maximum recovery of liquid hydrocarbon from the well fluid is the optimum set of pressures, which is the target of this work.</p><p>A computer model is used to find the optimum separator pressures. The model employs the Peng-Robinson equation of state (Peng and Robinson 1976) for volatile oil. The application of t</p> ... Show More
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Publication Date
Fri Oct 20 2023
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Fibrewise Multi-Perfect Topological Spaces
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The essential objective of this paper is to introduce new notions of fibrewise topological spaces on D that are named to be upper perfect topological spaces, lower perfect topological spaces, multi-perfect topological spaces, fibrewise upper perfect topological spaces, and fibrewise lower perfect topological spaces. fibrewise multi-perfect topological spaces, filter base, contact point, rigid, multi-rigid, multi-rigid, fibrewise upper weakly closed, fibrewise lower weakly closed, fibrewise multi-weakly closed, set, almost upper perfect, almost lower perfect, almost multi-perfect, fibrewise almost upper perfect, fibrewise almost lower perfect, fibrewise almost multi-perfect, upper* continuous fibrewise upper topol

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Publication Date
Sun Apr 29 2018
Journal Name
Iraqi Journal Of Science
Solving Flexible Job Shop Scheduling Problem Using Meerkat Clan Algorithm
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Meerkat Clan Algorithm (MCA) that is a swarm intelligence algorithm resulting from watchful observation of the Meerkat (Suricata suricatta) in the Kalahari Desert in southern Africa. Meerkat has some behaviour. Sentry, foraging, and baby-sitter are the behaviour used to build this algorithm through dividing the solution sets into two sets, all the operations are performed on the foraging set. The sentry presents the best solution. The Flexible Job Shop Scheduling Problem (FJSSP) is vital in the two fields of generation administration and combinatorial advancement. In any case, it is very hard to accomplish an ideal answer for this problem with customary streamlining approaches attributable to the high computational unpredictability. Most

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Publication Date
Thu Feb 10 2022
Journal Name
Iraqi Journal Of Science
Determining the optimum conditions for bioemulsifier produced by Rhizobium leguminosarum biovar viciae isolated from Vicia faba root nodules
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The tested isolate of Rhizobium leguminosarum bv. viciae was isolated from root nodules of vicia faba plant from Baghdad ,the isolated bacteria was examined for bioemulsifier production when growing in mineral salt medium that containing 1% sunflower oil as sole carbon source . Rhizobium isolate was able to produce bioemulsifier with initial emulsification index E24% was 38%. Many of physical and nutritional cultural conditions for optimum emulsifier production was examined including : pH , temperature ,incubation period ,carbon and nitrogen source. The maximum bioemulsifier production form Rhizobium isolate was 64.5% when bacteria growing in mineral salt medium with pH 9 ,incubated at temperature 30 ºC , incubation period was 10 days ,

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Publication Date
Sun Jul 02 2023
Journal Name
Iraqi Journal Of Science
A secure Search over Distributed Data
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In recent years, due to the economic benefits and technical advances of cloud
computing, huge amounts of data have been outsourced in the cloud. To protect the
privacy of their sensitive data, data owners have to encrypt their data prior
outsourcing it to the untrusted cloud servers. To facilitate searching over encrypted
data, several approaches have been provided. However, the majority of these
approaches handle Boolean search but not ranked search; a widely accepted
technique in the current information retrieval (IR) systems to retrieve only the top–k
relevant files. In this paper, propose a distributed secure ranked search scheme over
the encrypted cloud servers. Such scheme allows for the authorized user to

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Publication Date
Fri Apr 26 2019
Journal Name
Journal Of Contemporary Medical Sciences
Breast Cancer Decisive Parameters for Iraqi Women via Data Mining Techniques
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Objective This research investigates Breast Cancer real data for Iraqi women, these data are acquired manually from several Iraqi Hospitals of early detection for Breast Cancer. Data mining techniques are used to discover the hidden knowledge, unexpected patterns, and new rules from the dataset, which implies a large number of attributes. Methods Data mining techniques manipulate the redundant or simply irrelevant attributes to discover interesting patterns. However, the dataset is processed via Weka (The Waikato Environment for Knowledge Analysis) platform. The OneR technique is used as a machine learning classifier to evaluate the attribute worthy according to the class value. Results The evaluation is performed using

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Publication Date
Sat Jul 28 2018
Journal Name
Journal Of Engineering
Enhanced Oil Recovery using Smart Water Injection
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Smart water flooding (low salinity water flooding) was mainly invested in a sandstone reservoir. The main reasons for using low salinity water flooding are; to improve oil recovery and to give a support for the reservoir pressure.

In this study, two core plugs of sandstone were used with different permeability from south of Iraq to explain the effect of water injection with different ions concentration on the oil recovery. Water types that have been used are formation water, seawater, modified low salinity water, and deionized water.

The effects of water salinity, the flow rate of water injected, and the permeability of core plugs have been studied in order to summarize the best conditions of low salinity

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Publication Date
Fri Apr 28 2017
Journal Name
جامعة بغداد- كلية اللغات- قسم اللغة العبرية
המבנה המורפולוגי של מונחי המטבח בלשון העברית
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This research sheds light on the morphological construction of kitchen terms in Hebrew language, especially methods of derivation, by offering an extensive review of the most important methods of morphological derivation. The field of kitchen terms is a fertile and rich field, where we see daily production of new kitchen tools which require suitable names with specific meanings. Morphologically, the research interested in methods of morphological derivation. So as to know and identify the common and effective methods to derive the kitchen terms in Hebrew language, in addition to put a special glossary of these terms. The research found that most of the kitchen terms were derived according to the methods of derivation prevailing in Hebrew la

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