Photosynthetic and biochemical characterization of in vitro-derived African violet (<i>Saintpaulia ionantha</i>H. Wendl) plants to ex vitro conditions
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(19)
Publication Date
Sat Feb 01 2025
Journal Name
Pharmaceutical Nanotechnology
Preparation, <i>In-vitro, Ex-vivo</i>, and Pharmacokinetic Study of Lasmiditan as Intranasal Nanoemulsion-based <i>In Situ</i> Gel
Background:
Objective:
Method:
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Bioavailability study
ex vivo permeation study
C-max
Lasmiditan
nanoemulsion-based in situ gel (NEIG)
T-max
aqueous-LAS suspension.
Lasmiditan (LAS) is a recently developed antimigraine drug and was approved in October, 2019 for the treatment of acute migraines; however, it suffers from low oral bioavailability, which is around 40%.
This study aimed to improve the LAS bioavailability via formulation as nanoemulsionbased in situ gel (NEIG) given intranasally and then compare the traditional aqueous-LASsuspension (AQS) with the two successful intranasal prepared formulations (NEIG 2 and NEIG 5) in order to determine its relative bioavailability (F-relative) via using rabbits.
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(7)
Publication Date
Wed Jan 01 2020
Journal Name
Research Journal Of Pharmacy And Technology
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(8)
Publication Date
Wed Jul 22 2015
Journal Name
Plant Growth Regulation
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(11)
Publication Date
Mon Jun 01 2020
Journal Name
Life Sciences
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(5)
Publication Date
Sat Oct 05 2024
Journal Name
Apos Trends In Orthodontics
Novel cytotoxicity of nano-coated orthodontic micro-implants: An <i>in vitro</i> study
Objectives:
Material and Methods:
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Many attempts have been made to modify the surface of orthodontic micro-implants and prevent the development of microbes by coating them with antimicrobial nanoparticles (NPs). The purpose of the present study was to evaluate the cytotoxicity of different NPs, namely, TiO2 and zinc oxide (ZnO) NPs, that are used to coat titanium orthodontic micro-implants.
Thirty orthodontic micro-implants were included in this study. Those were divided into three groups: control group without coating, TiO2-coated orthodontic micro-implants, and TiO2- and ZnO-coated orthodontic micro-implants. Scann
Publication Date
Tue Sep 05 2017
Journal Name
Cell Adhesion & Migration
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(30)
Publication Date
Thu Sep 01 2016
Journal Name
Journal Of Ocular Pharmacology And Therapeutics
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(20)
Publication Date
Thu Jul 11 2019
Journal Name
Turkish Journal Of Pharmaceutical Sciences
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(12)
Publication Date
Tue Jan 01 2019
Journal Name
Indian Journal Of Forensic Medicine & Toxicology
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(1)
Publication Date
Fri Nov 01 2024
Journal Name
Heliyon
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