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Analysis of Docetaxel Adverse Drug Reactions: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database

Docetaxel is an effective treatment approved for many types of cancers, but its effectiveness in clinical practice can be compromised by significant occurrence of adverse drug reactions. The aim of the current study was to measure the distribution of adverse drug reactions of docetaxel reported in Iraq and to assess the causality, severity, seriousness, preventability, expectedness and outcome of these adverse reactions. A retrospective study conducted on individual case safety reports from the Iraqi Pharmacovigilance Center / Ministry of Health. The study included 118 individual case safety report containing 236 adverse drug reactions.Most of the adverse drug reactions were related to skin and subcutaneous tissue disorders(26.7%), followed by respiratory, thoracic and mediastinal disorders (20.8%), gastrointestinal disorders (17.4%) and general disorders and administration site conditions (10.6%). The majority of these reactions with possible causality (68.6%), moderate severity (75.4%), expected (80.5%), possibly preventable (93.2%), and serious (80.5%). In addition the most common outcome of adverse drug reactions was recovered / resolved (46.19%).

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Publication Date
Sun Mar 15 2020
Journal Name
Iraqi Journal Of Science
On Semiannahilator Supplement Submodules

Let R be associative; ring; with an identity and let D be unitary left R- module; . In this work we present semiannihilator; supplement submodule as a generalization of R-a- supplement submodule, Let U and V be submodules of an R-module D if D=U+V and whenever Y≤ V and D=U+Y, then annY≪R;. We also introduce the the concept of semiannihilator -supplemented ;modules and semiannihilator weak; supplemented modules, and we give some basic properties of this conseptes

Publication Date
Tue Nov 01 2011
Journal Name
Australian Journal Of Basic And Applied Sciences
Closure Operators on Graphs

The aim of this paper is to generate topological structure on the power set of vertices of digraphs using new definition which is Gm-closure operator on out-linked of digraphs. Properties of this topological structure are studied and several examples are given. Also we give some new generalizations of some definitions in digraphs to the some known definitions in topology which are Ropen subgraph, α-open subgraph, pre-open subgraph, and β-open subgraph. Furthermore, we define and study the accuracy of these new generalizations on subgraps and paths.

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Publication Date
Tue Jan 01 2019
Journal Name
Revista Aus
On Simply* Compact Spaces

In the present paper, a simply* compact spaces was introduced it defined over simply*- open set previous knowledge and we study the relation between the simply* separation axioms and the compactness, in addition to introduce a new types of functions known as 𝛼𝑆 𝑀∗ _irresolte , 𝛼𝑆 𝑀∗ __𝑐𝑜𝑛𝑡𝑖𝑛𝑢𝑜𝑢𝑠 and 𝑅 𝑆 𝑀∗ _ continuous, which are defined between two topological spaces.

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Publication Date
Sun Jan 01 2017
Journal Name
International Mathematical Forum
On mildly-regular space

In this paper mildly-regular topological space was introduced via the concept of mildly g-open sets. Many properties of mildly - regular space are investigated and the interactions between mildly-regular space and certain types of topological spaces are considered. Also the concept of strong mildly-regular space was introduced and a main theorem on this space was proved.

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Publication Date
Wed May 24 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
On Almost Bounded Submodules

        Let R be a commutative ring with identity, and let M be a unitary R-module. We introduce a concept of almost bounded submodules as follows: A submodule N of an R-module M is called an almost bounded submodule if there exists xÃŽM, xÏN such that annR(N)=annR(x).

        In this paper, some properties of almost bounded submodules are given. Also, various basic results about almost bounded submodules are considered.

        Moreover, some relations between almost bounded submodules and other types of modules are considered.

 

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Publication Date
Sun Oct 30 2022
Journal Name
Iraqi Journal Of Science
Remarks on Ultrasemiprime algebras

        Every finite dimensional normed algebra is isomorphic to the finite direct product of  or , it is also proved these algebras are ultrasemiprime algebras. In this paper, the ultrasemiprime proof of the finite direct product of  and  is generalized to the finite direct product of any ultrasemiprime algebras.

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Publication Date
Sun May 17 2020
Journal Name
Iraqi Journal Of Science
On Semiannahilator Supplement Submodules

Let R be associative; ring; with an identity and let D be unitary left R- module; . In this work we present semiannihilator; supplement submodule as a generalization of R-a- supplement submodule, Let U and V be submodules of an R-module D if D=U+V and whenever Y≤ V and D=U+Y, then annY≪R;. We also introduce the the concept of semiannihilator -supplemented ;modules and semiannihilator weak; supplemented modules, and we give some basic properties of this conseptes.

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Publication Date
Tue May 30 2023
Journal Name
Iraqi Journal Of Science
On gw-Prime Submodules

     Our aim in this work is to investigate prime submodules and prove some properties of them. We study the relations between prime submodules of a given module and the extension of prime submodules. The relations between prime submodules of two given modules and the prime submodules in the direct product of their quotient module are studied and investigated.

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Publication Date
Fri Jun 30 2023
Journal Name
Iraqi Journal Of Science
On Subspace Codisk-Cyclicity

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Publication Date
Thu Dec 08 2022
Journal Name
Aequationes Mathematicae
On graceful antimagic graphs

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